PLoS ONE
Articles in this Issue
Not just two languages: Using variation in language experience to understand how cognitive resources shape syntactic processing
Individuals who learn and use two languages come to that experience in many different ways. Recent studies have shown that to understand bilingualism, it is necessary to characterize the variation in...
RETRACTED: Advanced machine learning-guided optimization platform for high-yield soluble expression of Pseudomonas aeruginosa exotoxin A in engineered Escherichia coli strains
Background The recombinant production of Pseudomonas aeruginosa exotoxin A (ETA), a critical component for immuno...
The impact of trade frictions on the financial vulnerability of Chinese households
In recent years, escalating trade frictions have exerted substantial shocks on the financial security of Chinese households. Drawing on data from the China Family Panel Studies (CFPS) for 2014–2022, t...
Evaluation of long-range temporal correlations during overt and covert attention in a steady state visual evoked potential based brain-computer interface
Gaze control is required for successful brain-computer interface (BCI) operation in different paradigms. It has been shown that the performance of a steady-state visual evoked potential-based BCI is l...
Pain processing and pain assessment in Huntington’s disease: Study protocol of the Huntington’s disease - PAIN study
Background Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease that causes motor ( e.g.,...
Protocol for a scoping review on information and communication technologies (ICTs) in community practice
Introduction There is a growing literature connecting information and communication technologies (ICTs) to community-based practices including community organizing, community devel...
Cultural participation and life satisfaction: an investigation across different family backgrounds
The economic and social impact of cultural participation has recently become once more a subject of interest for policy-making, especially as a driver potentially affecting social inclusion and qualit...
The impact of imaginary future generations on the preference for carbon tax schemes
Carbon pricing instruments have been found to be an effective incentive to mitigate climate change, but that surely increases the burden on the current generation. Some previous experiments found that...
Judgments of American English male talkers who are perceived to sound gay or straight: Which personal attributes are associated with each group of talkers?
Upon hearing a spoken utterance, listeners associate certain attributes (e.g., emotional) with self-identified gay male talkers and other attributes (e.g., reserved) with self-identified straight male...
Human resistin is critical to activation of the NLRP3 inflammasome in macrophages
Elevated levels of human resistin (hResistin) have been associated with diverse inflammatory diseases, but the precise mechanisms through which hResistin’s many inflammatory effects contribute to the...
Variation analysis of growth traits and medicinal components in different provenances of Polygonatum cyrtonema based on heterogeneous garden experiment
Polygonatum cyrtonema is a valuable medicinal and edible plant whose sustainable utilization is challenged by wild resource depletion and germplasm degradation. This study establis...
Navigating international academic collaboration: The Arabic translation and cultural adaptation of the Quality Maternal and Newborn Care Framework index
Background The Quality Maternal and Newborn Care Framework index (QMNCFi) is a validated English-language instrument developed to assess women’s experiences during pregnancy, child...
Genomic dissection of methane emission traits in cattle: A meta-GWAS and heritability analysis across populations
Enteric methane emissions from ruminants represent a significant contributor to agricultural greenhouse gases, necessitating precise genetic tools to guide mitigation strategies. This study aimed to i...
Structural transformation of a hydrogel-forming cell division protein ZapB of multidrug resistant Klebsiella pneumoniae with small molecules
Septal ring assembly protein ZapB (EMR18431.1) is involved in Z-ring formation, and nucleoid segregation during the bacterial cell division . It promotes cell division in the initial stages of the cel...
Modeling insurance claims using Bayesian nonparametric regression
Predicting future insurance claims using observed covariates is essential for actuaries in setting appropriate insurance premiums. For this purpose, actuaries commonly employ parametric regression mod...
Featuring the application of biochemistry in dental practice through a self-directed assignment: A descriptive study
Background With advancements in the fields of treatment, diagnosis, and genomics, knowledge of cellular biochemistry is becoming increasingly crucial for ora...
Unveiling the Multifaceted Dynamics of Breast Cancer: A Copula Regression Approach to Modeling and Predicting Outcomes
This study examines the application of flexible copula regression models to analyze the complex interdependencies among clinical variables in breast cancer data. As the most commonly diagnosed cancer...
WHO five moments for medication safety among diabetic patients in Saudi Arabia
Background Diabetic patients are particularly vulnerable to medication errors. Assessing adherence to the WHO Five Moments for Medication Safety among diabetic patients is essentia...
Association of serum irisin levels with postoperative cognitive dysfunction in older patients following total hip or knee arthroplasty: A prospective observational study
Background Postoperative cognitive dysfunction (POCD) is a frequent complication in older patients undergoing hip and knee arthroplasty. While irisin has demonstrated benefits in n...
Digital referral experiences within Australian general practice: Insights from Chronic Obstructive Pulmonary Disease (COPD) care as an exemplar
Background Digital referral platforms can strengthen communication between primary and specialist care and improve continuity for people with COPD. However, adoption in Australian...
Exploring barriers and enablers to diabetes self-care practice in Ethiopia, 2025: A qualitative systematic review
Introduction Diabetes mellitus is a growing public health concern in Ethiopia, with increasing prevalence and a high proportion of undiagnosed cases. Effective self-care is crucial...
Optimizing topical antibiotic delivery in dogs: Tear film pharmacokinetics of moxifloxacin following pre-treatment with hyaluronic acid
Purpose To evaluate the impact of pre-treatment with mucoadhesive polymers on tear film concentrations of topically administered moxifloxacin in dogs....
The identification of metabolites from gut microbiota in HPV infection via network pharmacology
Human papillomavirus (HPV) infection continues to pose a significant global health challenge. Although gut microbial metabolites have been associated with HPV infection, the mechanisms underlying this...
The effectiveness of dry needling at myofascial trigger points for knee disorders: A quantitative synthesis of randomized controlled trials
Purpose Dry needling (DN) targeting myofascial trigger points (MTrPs) has been proposed as a treatment for knee disorders, including knee osteoarthritis (KOA) and patellofemoral pa...
Psychological help-seeking behaviours amongst those living with Inflammatory Bowel Disease; A cross-sectional, descriptive, correlational study
Aim To explore the help-seeking preferences and behaviours of those living with Inflammatory Bowel Disease for negative emotions....