PLoS ONE
Articles in this Issue
A new target: AlkBH2 promotes bladder cancer by upregulation of inflammation
A close relationship exists between inflammation and cancer. Recent studies have highlighted inflammation as a significant contributor to the progression of bladder cancer. However, the role of alkyla...
Tracing the pathways to Yathrib (Al-Madinah): A GIS-based analysis of settlement patterns and ancient trade networks
Ancient human activities in the arid Arabia peninsula are considered one of interesting research subjects in the landscape archaeological field to understand the relationships between human occupation...
Perspectives on hospice and palliative care in an academic setting: An exploratory interview study with patients and relatives to inform the development of an academic inpatient hospice
Background Although palliative and hospice care are essential for individuals with life-limiting illnesses, academic inpatient hospices, which combine care with research and educat...
Use of implementation science models, theories, and frameworks in pediatric rehabilitation: Protocol for a scoping review
Introduction Implementation science frameworks – including process models, determinant frameworks, classic theories, implementation theories, and evaluation frameworks – are increa...
Prehabilitation before cancer surgery in the UK National Health Service: what services exist, and how do they address health inequalities?
Objectives To identify and map prehabilitation services for patients preparing for cancer surgery in the UK National Health Service (NHS) and understand how issues of accessibility...
Nationwide trends and regional variation in intravitreal injections and anti-VEGF agent use in Japan from 2017 to 2022: An analysis of the NDB Open Data
Intravitreal injections are an essential treatment modality for retinal vascular and macular diseases, yet nationwide evidence describing long-term trends, regional variation, drug composition, season...
A novel application tunnel in combination with medical training reduces stress induced by frequent intraperitoneal injections and blood draws in mice
Handling-induced stress represents a major burden on laboratory mice and is heavily influenced by the handling technique. As such, tail-handling induces much higher stress than cup- or tunnel-handling...
Microbial fuel cells for wastewater treatment and electricity production: A multi-platform simulation workflow
The need for sustainable energy generation and efficient wastewater treatment continues to motivate technologies that integrate energy recovery with environmental remediation. Here, a microbial fuel c...
Anaerobic bacteria Cetobacterium sp. nov C33 plays a crucial role in the intestinal microbial balance and regulation of gene expression to immune and metabolic responses in Nile tilapia
Aquaculture ranks among the largest global food production industries, with Nile tilapia ( Oreochromis niloticus ) being one of the most widely farmed species....
Determinants and disparities in skilled birth attendants during childbirth in Bangladesh: A study of machine learning and decomposition analysis
This study delves into the determinants and socioeconomic disparities influencing the utilization of Skilled Birth Attendants (SBAs) for childbirth in Bangladesh, deploying advanced statistical and ma...
Integration of HIV, Hepatitis B, and C, and sexually transmitted infections services: A scoping review of the benefits and challenges
Background Integrating clinical programs and services is a cost-effective approach that can improve health and system outcomes. This review aimed to provide an overview of the bene...
Adaptive strategies of Egyptian crowfoot grass (Dactyloctenium aegyptium (L.) Willd): Germination responses to environmental factors
Egyptian crowfoot grass (Dactyloctenium aegyptium (L.) Willd.) is a troublesome C 4 grass weed that competes with crops such as rice (Direct Seeded Rice), sugar...
Serum cholinesterase as a biomarker for sepsis-associated immunosuppression via Hub gene RORA
Background Sepsis-induced immunosuppression is a key factor contributing to high mortality rates. However, suitable biomarkers for routine clinical monitoring of immune function ar...
Interrelated adolescent-level food insecurity and common mental health disorders in Harari Region, Ethiopia: A cross-sectional study
Background Global adolescent-level food insecurity (AFI) and common mental disorders (CMD) represent a significant public health burden. While household-level food security is know...
Correction: Diversity of root system architecture and root-shoot biomass allocation in industrial hemp (Cannabis sativa L.)
Spatiotemporal variability of dairy manure temperature during storage in earthen pits: Associations with meteorological factors
Manure storage is a critical component of nutrient management in dairy systems, but it is also a major source of greenhouse gas emissions and nutrient losses. Temperature regulates microbial activity...
Association between cannabis use and result of COVID-19 testing among scholarised adolescents in Andalusia: A cross-sectional study
Aims The COVID-19 pandemic may have impacted cannabis use among the adolescent population. Therefore, it is important to understand the potential factors linking cannabis use to CO...
Comparison of unbiased metagenomic next generation sequencing to targeted multiplex diagnostic assays for the detection of respiratory viruses
Objectives Accurate diagnosis of existing and emerging respiratory pathogens is important. We evaluated the capability of unbiased metagenomic next generation sequencing (mNGS) to...
Complete genome and functional insights into Microbacterium sp. strain FBCC-B4120, a novel freshwater isolate with diverse biotechnological traits
The genus Microbacterium encompasses a diverse group of Actinobacteria with broad ecological distribution and functional versatility. Here, we report the comple...
Performance and mechanism analysis of DMP-30 modulated waterborne epoxy resin emulsified asphalt
The rapid breakage of emulsified asphalt can hinder the curing process of epoxy resin, thereby compromising the performance of waterborne epoxy resin emulsified asphalt (WEREA) and its mixture. Introd...
FedEmoNet: Privacy-preserving federated learning with TCN-Transformer fusion for cross-corpus speech emotion recognition
Federated learning offers a promising path toward privacy-preserving speech emotion recognition, yet existing approaches remain confined to single-corpus evaluation, lack formal differential privacy g...
Research on multi-sensor fusion architecture for highway area hazard monitoring based on UAVs
Highway area geohazards pose a serious threat to traffic safety, and traditional monitoring echniques struggle to meet the requirements for high precision and real-time capability, while existing unma...
Integrative taxonomy of Haemaphysalis (Acari: Ixodidae) from the Western Ghats, India: Morphological and molecular characterization and implications
Haemaphysalis ticks (Ixodidae) are important vectors of pathogens affecting humans and animals, yet their genetic diversity and subgeneric relationships remain insufficiently resol...
Exploring the evidence of direct threats to cetaceans from maritime vessels: A systematic map
Cetaceans face a multitude of well-recognised anthropogenic threats, many of which can be attributed to the activities of marine vessels that are increasing in number throughout the world’s oceans. Th...
Analysis and source identification of dust event in Khuzestan province using MODIS and SENTINEL satellite data and HYSPLIT model (2018–2022)
Dust events present significant environmental and public health challenges in Khuzestan Province, Iran, severely affecting air quality, human health, and ecosystems. This study analyzed dust dynamics...