PLoS ONE
Articles in this Issue
Computational modeling of intravitreal ranibizumab kinetics: Predicting macular drug concentration and half-life
Ranibizumab is a key anti-VEGF therapeutic used to improve treatment efficacy and reduce injection frequency in neovascular retinal diseases. Because experimental pharmacokinetic data in humans are li...
Clinical evaluation of the i-gel Plus supraglottic airway in Japanese patients: A prospective observational study
Background The i-gel® Plus, a new supraglottic airway, has a high oropharyngeal leak pressure of 32 ± 7 cmH 2 O i...
Richness and biogeography of Pteridoflora in montane forests of eastern Mexico
This study compiles and updates the checklist of ferns and lycophytes from the Sierra Madre Oriental (SMOR), Mexico. We analyzed the distribution and richness of these groups of seedless vascular plan...
Coupled numerical simulation and strategy optimization of land subsidence caused by groundwater extraction in Langfang City
Numerical simulation is an effective method for studying land subsidence caused by groundwater extraction. In this paper, the land subsidence in Langfang City was analyzed by using a coupled fluid-sol...
Retraction: Chemosensitizing indomethacin-conjugated dextran-based micelles for effective delivery of paclitaxel in resistant breast cancer therapy
Correction: Formulations of poly(vinyl alcohol) functionalized silk fibroin nanoparticles for the oral delivery of zwitterionic ciprofloxacin
Sensorimotor integration and functional mobility in early-stage Parkinson’s disease: A cross-sectional study using clinically feasible assessments
Early-stage Parkinson’s disease (PD) often features subtle sensorimotor integration deficits that may precede noticeable motor decline. This study examined how proprioceptive acuity, balance performan...
Federated high order tensor fusion for privacy preserving multimodal social media analysis
The rapid evolution of social networks has positioned multimodal content, including text, images, and audio, as a pivotal medium for self-expression and public sentiment analysis. However, existing mu...
Facilitators of and barriers to participation in Long COVID research: A qualitative analysis
Background Meeting recruitment targets in an expeditious manner is essential to the successful completion of any research project. However, despite the high prevalence and debilita...
Prevalence and determinants of parental refusal of human papillomavirus vaccination in Morocco: A multicenter cross-sectional study
Introduction Vaccination against the human papillomavirus (HPV) is an effective way to avert cervical cancer. However, acceptance in Morocco remains inadequate. The aim of this stu...
Sex differences in global burden of Congenital Heart Anomalies in children under five from 1990 to 2021
Background Congenital heart anomalies (CHA) significantly contribute to childhood morbidity and mortality worldwide. Understanding sex-specific differences and their association wi...
Four moral models of global health security
Global health security is concerned with the response to infectious disease outbreaks across international borders. However, its precise nature and scope are contested because of lack of agreement abo...
Seafloor video-acoustic monitoring in a Greenlandic glacial fjord records hyperbenthos, backward-swimming fish, and narwhals
Autonomous video-acoustic monitoring at the sea-floor can improve our understanding of poorly documented ecosystems and help interpret active or passive acoustic data, but it has been rarely carried o...
Effect of hysterectomy on the risk of ovarian cancer: A South Korean national cohort study
Background Hysterectomy is a common gynecological surgery, but its long-term impact on ovarian cancer risk remains unclear, particularly in Asian populations....
Stability of corneal endothelial monolayers in the presence of magnetic particles in a rotating magnetic field
Magnetic particles have significant potential as novel theranostics due to the relative ease of surface modification for targeting molecules or regions of diseased tissues, coupled with remote...
Marrying for power: Gendered alliances in mafias
Drawing on judicial records documenting 770 inter-clan alliances through 906 marriages among 623 ’Ndrangheta clans, we analyze how matrimonial ties relate to power and cohesion within the organization...
Predictors of Post-Traumatic Stress Symptoms after musculoskeletal trauma
Background Post-traumatic stress symptoms (PTSS) are common following musculoskeletal trauma and are associated with poorer recovery, disability, and reduced quality of life. Altho...
Propensity to trust in Large Language Models
Trust is central to collaborative settings in which large language models (LLMs) are increasingly deployed. Yet little is known about whether LLMs exhibit a propensity to trust...
A citizen scientist’s survey provides insights into the movements of Atlantic and Gulf states’ populations of Black Skimmers (Rynchops niger)
Ornithologists are increasingly using field readable bands—plastic rings with alphanumeric codes that are visible from a distance—to study bird populations. Because of this advance, a member of the pu...
Climatic niche properties shape treefrog diversity
A suite of ecological hypotheses has been proposed to explain why more species are found in the tropics. Most of these hypotheses consider the geography of climate as a major determinant of richness,...
Endothelial activation and stress index in risk stratification and treatment optimization for critically ill patients with acute kidney injury: A retrospective cohort study from MIMIC-Ⅳ database
Background Endothelial dysfunction is critical in the pathogenesis of acute kidney injury (AKI). It sought to investigate the role of endothelial activation and stress index (EASIX...
Exploring the effects of task complexity and translation anxiety on EFL learners’ translation performance: Evidence from a mixed-design study
While the impact of task complexity on translation performance has received considerable attention, relatively little research has explored whether affective factors such as translation anxiety modera...
Impact of the COVID-19 pandemic on sex-related disparities in cystic fibrosis healthcare utilization and outcomes: A population study
Background The COVID-19 pandemic disrupted healthcare utilization and access for many, with persons living with pre-existing pulmonary conditions like cystic fibrosis (pwCF) having...
Non-concussive head impacts sustained during American football correlate with changes in gut microbiome diversity and composition
Non-concussive head impacts (NHIs) are a significant health concern among at-risk groups, including athletes and military personnel. NHIs are hits to the head or head acceleration events (HAEs) that d...
Ancient East Asian dog lineage is revealed by genome of ancient Korean dogs
Dogs form a monophyletic clade comprising three major sublineages: Eastern Eurasian, Western Eurasian, and sled dog lineages. While ancient genomic studies have clarified relationships within the latt...