PLoS ONE
Articles in this Issue
Trends of laboratory nonhuman primate licensing in China between 2020 and 2024: A national database analysis
Nonhuman primates are critical translational models in biomedical research due to their genetic, anatomical, and physiological similarities to humans. China, once a dominant global supplier of captive...
Identification of a diagnostic metabolomic fingerprint in plasma for eosinophilic granulomatosis with polyangiitis
Objective Eosinophilic granulomatosis with polyangiitis (EGPA) was a rare systemic vasculitis characterized by eosinophilia, asthma, and necrotizing vasculitis. Metabolic dysregula...
Adaptive elastic convolution-based YOLO for peripheral blood smear cell detection
Peripheral blood smear analysis continues to be important for the diagnosis of various hematologic conditions, although automated systems often experience difficulties due to the variety of cell types...
Oral carbohydrate sensing enhances prefrontal cortex oxygenation, reduces perceived exertion, and improves high-intensity cycling performance: A randomized crossover trial
Purpose Carbohydrate mouth rinsing (CHO-MR) and music listening (MUS) are non-metabolic interventions proposed to attenuate cognitive and perceptual fatigue during exercise. Howeve...
Retraction: Does Occupational Exposure to Solvents and Pesticides in Association with Glutathione S-Transferase A1, M1, P1, and T1 Polymorphisms Increase the Risk of Bladder Cancer? The Belgrade Case-Control Study
Understanding teamwork experiences of neurodivergent students: A phenomenological exploration of conflict and collaboration in engineering teams
Neurodivergent individuals have been systematically excluded from employment opportunities, meaning that we know little about lived experiences within neurodiverse teams. To fill this gap, the current...
Comparative genomics of human brain and immune gene preservation across species
The study of human gene evolution along primate and non-primate lineages has attracted increasing attention. Previous research demonstrated associations between the origin of genes and their expressio...
Non-viral in vivo electroporation-based chromosomal engineering and repair assessment in the murine uterine epithelium
Chromosomal rearrangements generated by CRISPR/Cas systems are valuable for studying genomic architecture and repair mechanisms. However, most in vivo approache...
A multi-view TSK fuzzy system with deformable Gaussian membership functions and rule-level attention for classification
This study presents a novel multi-view TSK fuzzy system that integrates deformable Gaussian membership functions with a rule-level attention mechanism (MDA-TSK-FS), aiming to improve the modeling capa...
Study on the influence of the mass eccentric wheelset on the wheel polygonal wear of high-speed trains
In the paper, the finite element model of the wheelset-track system is established, and the explicit transient dynamic analysis method is used to study the dynamic response. The research results show...
Minimally-invasive resection of deep-seated subcortical and intraventricular lesions using an integrated camera-port system: A retrospective case series
Minimally invasive neurosurgery using port-based systems has gained popularity over the past decade to access deep-seated lesions within the brain. These devices typically necessitate use of separate...
Spatiotemporal analysis of psychoactive drug consumption in Brazil during the COVID-19 pandemic
The COVID-19 pandemic had a significant impact on Brazil, although its effects were not homogeneous across the country. Socioeconomic disparities may influence epidemiological patterns during health e...
Nourishing futures: Assessing nutritional health among children under-five years of age belonging to a particularly vulnerable tribal community in Southern India
Malnutrition is a major public health concern among tribal communities, where children face higher risk due to socio-economic disadvantages, poor healthcare access, and inadequate diets. Despite gover...
Seasonal changes in the distributions of fish and zooplankton across the Barents Sea Polar Front
Oceanic fronts are often characterized by high primary productivity and increased localized levels of species diversity and biomass; this is due in part to the mixing of distinct water masses as well...
Unveiling post-vaccination proteomic signatures in SARS-CoV-2 infection-naïve individuals associated with Omicron breakthrough infections
Background Given the persistence of the SARS-CoV-2 virus, it is important to understand the proteome associated with breakthrough infections among COVID-19 vaccinated individuals....
WGS identifies Lynch syndrome (LS) patients and uncovers a large family with MSH2-related LS in Southern Thailand
This study aimed to investigate Lynch Syndrome (LS)-related germline variants among Southern Thai patients with colorectal cancer (CRC) and other LS-associated cancers who met the revised Bethesda gui...
The effectiveness of Chuna manual therapy based on radiographic malposition diagnosis in patients with non-acute low back pain: A study protocol for a randomized, assessor-blind, parallel-group, controlled trial
Background Chuna manual therapy is a Korean therapeutic modality that is widely used for treating low back pain. First, spinal alignment is radiographically assessed, followed by t...
Acaricidal activity of plant extracts against Amblyomma variegatum in Waghimra, Northeastern Ethiopia
Ticks are blood-feeding ectoparasites that cause significant economic losses by reducing animal productivity and damaging hides and skins. Ticks control and prevention strategies primarily rely on the...
Burden and predisposing factors of physical inactivity among adults in Africa: Systematic review and Meta-analysis
Introduction Physical inactivity is a primary driver of global mortality, data on its specific impact in Africa remains fragmented. We conducted this study to provide the first com...
Mediating reconciliation with God: Exploring divine forgiveness experiences during confession among Catholic priests from four Spanish-speaking countries
Divine forgiveness (DF), the subjective experience of being forgiven by a higher power after a transgression, remains understudied in psychology, particularly across diverse cultural and religious con...
Evaluating healthcare professionals’ readiness for community-based kangaroo mother care in resource-limited setting
Background Neonatal mortality remains a major public health challenge in low-resource settings. Community-Based Kangaroo Mother Care (cKMC) improves survival outcomes for preterm a...
Association between first-trimester cell-free fetal DNA levels and the risk of preterm birth and low birth weight: A propensity score-matched cohort study
Objective To investigate the association between the concentration of cell-free fetal DNA (cffDNA) in the first trimester and the risks of preterm birth (PTB) and low birth weight...
Toward Industry 5.0: A WebSocket–S7 Bridge for Low-Latency, IEC 61588-Compliant Digital Twins in Remote Industrial Automation
While Industry 4.0 established connectivity and automation as foundations of smart factories, the emerging vision of Industry 5.0 emphasizes human-centric, resilient, and sustainable systems. Within t...
Editorial Note: High atherogenic risk concomitant with elevated HbA1c among persons with type 2 diabetes mellitus in North Ethiopia
Synthesis, antioxidant capacity and aggregation of carotenoid-curcumin conjugates and hybrids
Both curcumin and carotenoids are good antioxidants and curcumin has a pleiotropic effect additionally. To combine the beneficial properties carotenoid succinates were coupled to curcumin via ester bo...