PLoS ONE
Articles in this Issue
Expression of Concern: Susceptibility mapping and zoning of highway landslide disasters in China
Research on the dynamic characteristics of a wind turbine drivetrain based on different control strategies for the generator-side inverter
Within the operational context of wind turbines (WTs), the dynamic properties of the drivetrain significantly influence the overall system stability. The implementation of both active and passive cont...
Framing artificial intelligence in Chilean digital press before and after the launch of ChatGPT: From concern to optimism
This article examines the evolution of AI framing in Chilean national digital media before and after the launch of ChatGPT in 2022. Through topic modeling and emotion analysis of 1,466 articles publis...
Extracting user profile via large language models and ontologies
Extracting user-specific profiles that include general personal information, such as hobbies, occupation, or age, is a valuable asset for systems like recommendation engines or personalized chatbots....
Scaffold-free 3D-cell co-culture model system for the study of metastatic cancer in the brain TME
Cancer involves complex and dynamic interactions among tumor, stromal, immune cells, and the surrounding matrix, however, the protected microenvironment of the brain limits direct access and the execu...
Correction: A mixed-methods multi-site case study of a person-centred intervention for constant observation in hospitals with people living with dementia
Patient activation among patients with type 2 diabetes and its association with perception of care, perceived autonomy support, sociodemographic and clinical characteristics
Background Patient activation is an important aspect of self-management in type 2 diabetes (T2DM) and a key component of the Chronic Care Model, whereby pati...
Tailoring Bayesian Additive Regression Trees (BART) for environmental mixture studies
Background Various methods have been developed to investigate the complex and collective effects of environmental mixtures on human health. Tree ensemble methods, such as Bayesian...
Warm realism in Chinese microdramas: A term frequency analysis of audience comments on The Puppy Laifu
Starting from the connotation of warm realism, this study analyzes the narrative characteristics of the warm realist microdrama The Puppy Laifu on the Douyin pl...
Single-cell transcriptomics of leukocyte-enriched human milk reveals a highly diverse and adapted myeloid compartment
Human milk is a bioactive fluid containing maternal leukocytes that support infant immune protection and development. Prior work has demonstrated the presence of atypical, non-granulocyte milk myeloid...
A remote monitoring system based on deep learning for real-time assessment of free flaps
Purpose Venous congestion is a major cause of postoperative free flap compromise, and early detection is crucial for improving flap salvage rates and patient outcomes. This study a...
Co-developing a survey on public understanding of sustainable clinical research: A study protocol
Background Clinical research is essential for medical advancement but contributes to carbon emissions through activities such as travel, data management, and laboratory processes....
Evaluation of the performance of large language models in responding to medical questions related to multiple sclerosis: A case study of large language models including ChatGPT, Gemini, Grok and Copilot
Objective To evaluate and compare the performance of four publicly available large language models—ChatGPT, Gemini, Copilot, and Grok—in answering medical questions related to Mult...
LiteFeatNet: A parameter-efficient and performance-centric deep learning model for multi-ocular disease identification using intermediate feature reduction from fundus images
Convolutional Neural Networks (CNNs) require a larger amount of input samples and computing resources to learn discriminative features for accurate identification of multiple retinal conditions, makin...
Visual navigation technology for autonomous driving robots based on strategic gradient-REINFORCE algorithm
Currently, autonomous driving robots face challenges of insufficient environmental perception and decision delay in visual navigation. To optimize the visual navigation performance of an autonomous dr...
Single dynamic structured light navigation for minimally invasive cervical pedicle screw insertion: Achieving complex design and precise puncture
Aim The aim of this study was to explore the preoperative design and intraoperative navigation for minimally invasive cervical pedicle punctures and to validate the feasibility and...
Multi-Omics and network-based exploration of potential molecular pathways in heart failure relevant to left bundle branch pacing response heterogeneity: Immune remodeling, hub gene identification, and drug repurposing hypotheses
Left bundle branch pacing (LBBP) has gained increasing attention as a novel pacing strategy, but its molecular underpinnings in the context of heart failure (HF) remain unclear due to limited LBBP-spe...
The radioactive 3D-printed template-assisted CT-guided 125I seed implantation for refractory bone metastases: A multicenter retrospective analysis of efficacy, safety, and immune function changes
Objective To comprehensively evaluate the efficacy and safety of three-dimensional (3D)-printed template-assisted CT-guided 125...
Using deep learning to identify inherited retinal diseases based on wide-field retinal imaging data
Objective To evaluate a novel image-based deep learning method for the automated identification of inherited retinal diseases (IRDs) and to explore the feasibility of predicting se...
Enhancing student data privacy in virtual learning with blockchain and advanced encryption
This study investigates a novel approach to enhance student data privacy in virtual collaborative learning environments (VCLEs). With the increasing adoption of VCLEs, students are generating substant...
Structural dynamics of the human Orai1 channel revealed by cryo-electron microscopy
The pore-forming Orai1 protein is an essential component of store-operated calcium entry (SOCE), a process vital to diverse cellular and physiological functions. Mutations in human Orai1 cause severe...
Translating research into action: Policy recommendations for strengthening antiretroviral therapy adherence in Ghana based on empirical evidence
Despite significant advances in antiretroviral therapy (ART) accessibility in Ghana, suboptimal adherence remains a critical challenge undermining treatment effectiveness. This article presents eviden...
Risk factors for healthcare-associated infections in children undergoing ECMO after cardiac surgery for congenital heart disease: A retrospective study
Objective To analyze the influencing factors of ECMO (extracorporeal membrane oxygenation)-related healthcare-associated infections in children after congenital heart disease (CHD)...
Healthy living environments create healthy physical activity-related habits (ELEVATE): A protocol for a smartphone-based mixed-method study
Physical inactivity remains a key risk factor for adverse public health outcomes, disproportionately burdening lower socioeconomic groups. While individual-level interventions may temporarily increase...
Relative golf performance between men and women: A comparison of absolute differences in performance between players on the PGA and LPGA tours considering physiological and anthropometric sex-based differences
Golf is an increasingly popular sport and presents fierce competition at the professional level. The Professional Golfers’ Association (PGA) Tour is the most prestigious professional men’s tour in gol...