PLoS ONE
Articles in this Issue
Barriers of last mile supply chain management and reproductive, maternal, new born, and child health product availability in Ethiopia
Background Despite notable advancements in Ethiopia’s health supply chain, critical bottlenecks persist at the last mile, particularly within health centres and health posts. This...
Association of 18F-fluorodeoxyglucose uptake with cardiac events in cardiac sarcoidosis during outpatient follow-up after immunosuppression
Background 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) is a pivotal tool for diagnosing cardiac sarcoidosis, but its prognostic value durin...
Factors associated with the occurrence and persistence of subthreshold and full attention-deficit hyperactivity disorder in women: A population-based epidemiological study
Background Attention-deficit hyperactivity disorder (ADHD) is one of the most frequent neurodevelopmental disorders in youth, and persists into adulthood in the majority of cases....
A strength reliability calculation method of tip relief gears
The gear tip relief affects the root bending stress and the contact pressure, which affects the strength reliability of the gear system. In this work, based on the proposed tip relief model and the me...
Cancer mutations in RAD51 and its paralogues
The RAD51 recombinase is central to repair of DNA damage arising from stalled or collapsed replication forks and DNA double strand breaks. Its essential role is revealed by the fact that this function...
The anti-angiogenic and anti-proliferative activity of n-benzoyl-3-phenyl isoserine derivative containing 1,2,3-triazole and quinoline rings
One of the biggest causes of death globally is cancer, which develops tumors characterized by angiogenesis and excessive cell proliferation. Cancer treatments targeting these pathways, especially thos...
Garlic (Allium sativum L.) yield and quality as affected by different integrated fertilizer levels in Wachemo University, southern Ethiopia
Production and productivity of garlic was constrained by many factors, among which soil fertility gradation and lack area specific fertilizer recommendation are the most important in Ethiopia. Thus, o...
Educational attainment and chronic HIV treatment adherence in southern and eastern Africa
Social policy makers frequently leverage formal schooling as a tool for curbing the HIV epidemic in sub-Saharan Africa. Yet, in the era of ‘Treatment as Prevention’, evidence about the association bet...
Clinical, humanistic, and economic burden of sickle cell disease in The Jazan Region, Saudi Arabia
Background Sickle cell disease (SCD) constitutes a significant public health concern in the Kingdom of Saudi Arabia (KSA), affecting a substantial proportion of the population in t...
Estrogen deficiency induces pelvic floor muscle atrophy via ERα/GLUT4 pathway
Pelvic floor dysfunction (PFD) is a common disease in women that seriously affects physical and psychological health. Menopause-associated estrogen reduction is one of the risk factors. However, the r...
SiPM-based optical sensing system for GIS partial discharge detection
The silicon photomultiplier (SiPM)-based optical detection method, which provides strong resistance to electromagnetic interference and high sensitivity, is attracting increasing attention. However, m...
Performance analysis of UAV-assisted coverage for cell edge
Unmanned aerial vehicles (UAVs), with their rapid and flexible deployment capabilities, have emerged as an effective solution for providing emergency wireless connectivity in scenarios where tradition...
Evaluating conflict-of-interest governance among Canadian medical societies using a novel assessment tool: A cross-sectional study
Background Medical societies shape clinical standards, develop practice guidelines, and provide continuing education to physicians. Many receive funding from pharmaceutical and med...
UBE2S emerges as a key driver in an NK cell–based prognostic model for clear cell renal cell carcinoma
Background Clear cell renal cell carcinoma (ccRCC) is highly heterogeneous, and robust biomarkers for risk stratification and therapeutic guidance remain limited....
Negotiating climate change: Science, policy, and the invisible power embedded in public discourse in Chinese social media
The use of social media has enabled diverse actors to engage in climate discourse, shifting climate change from a purely scientific issue to a broader global risk topic. Drawing on a decade of data fr...
Correction: Evaluating community pharmacists’ involvement in patient counselling and health education in Nairobi, Kenya: A cross-sectional study
Application of artificial intelligence based on contrast-enhanced CT imaging for predicting peritoneal metastasis in patients with T3/T4 stage gastric cancer
Gastric cancer, prevalent in East Asia, often presents with peritoneal metastasis at diagnosis, limiting surgical options and reducing survival rates. Given the low sensitivity of current diagnostic m...
Comparison of the performance of four clinical prediction rules for mortality in patients with COVID-19
Background Clinical prediction rules integrate clinical and laboratory variables to estimate outcomes, facilitating decision-making and optimizing resources, especially in high-dem...
Transvaginal tru-cut biopsy versus ascitic fluid cytology in gynaecologic tumours: A comparative diagnostic study
Objective To compare the diagnostic performance- including adequacy, accuracy, safety, sensitivity, specificity, and predicitve values- of transvaginal tru-cut biopsy and ascitic...
Out-of-pocket payments and associated factors among hypertensive patients insured under the National Health Insurance Scheme in a referral hospital, Ghana
Introduction Out-of-pocket (OOP) payments are a common component of healthcare financing in many low-and middle-income countries including Ghana. Despite implementation of the Nati...
Unsupervised seamless UAV image stitching via dense prediction
Image stitching is a critical preprocessing step in unmanned aerial vehicle (UAV)-based remote sensing, however, it remains challenging for conventional methods due to large parallax, high resolution,...
Optimising supervised machine learning algorithms predicting cigarette cravings and lapses for a smoking cessation just-in-time adaptive intervention (JITAI)
This study aimed to optimise the balance between participant burden and algorithm performance for predicting high-risk moments in a smoking cessation just-in-time adaptive intervention (JITAI) by syst...
The impact of environmental factors, sowing time, and soil conditions on the growth, yield, and resilience of Fagopyrum tataricum and Fagopyrum esculentum in Egyptian agroecosystems
Background Buckwheat ( Fagopyrum spp.) is a gluten-free pseudocereal with high nutritional and bioactive value, o...
Precision public health: A natural experiment on chronic high-contrast PM2.5 exposure and pulmonary function among older adults
Background: While fine particulate matter ( PM 2.5...
Strategic prioritization of blockchain diffusion factors by an integrated fuzzy Delphi-Dombi LMAW model: A case study in Bangladesh healthcare sectors
Over the recent years, blockchain technology has been an essential practice in enhancing profitability in healthcare supply chains, especially in emerging economies. Nevertheless, regulatory uncertain...