PLoS ONE
Articles in this Issue
D-dimer and lower limb ultrasound as prognostic factors for recurrent deep venous thrombosis and pulmonary embolism: A systematic review and meta-analysis
Venous thromboembolic disease is a chronic, recurrent condition. The optimal duration of anticoagulation therapy remains uncertain. We aim to evaluate D-dimer and lower limb ultrasonography as prognos...
Antibiotic dispensing practices and antimicrobial stewardship gaps in community pharmacies in Kakamega County, Kenya
Background Antimicrobial resistance (AMR) is a major global health threat, with sub-Saharan Africa bearing a disproportionate burden. Community-level antibiotic dispensing practice...
Mechanical behavior of cemented paste backfill under the coupled effect of loading rate and moisture content
This study investigates the coupled effects of loading rate and moisture condition on the mechanical behavior of cemented paste backfill (CPB). Uniaxial compression tests were conducted on CPB specime...
Evaluation of Colombian silk fibroin hydrogels functionalized with recombinant LSECtin for intervertebral disc tissue engineering
This study evaluated the potential of Colombian silk fibroin hydrogels functionalized with recombinant LSECtin (rLSECtin) for intervertebral disc tissue engineering. In silico...
Adaptive transgenerational plasticity through priming in response to neighbor density in Mimulus platycalyx
Transgenerational plasticity (TGP) allows organisms to epigenetically alter offspring phenotypes based on their own environmental experience. TGP is adaptive if offspring perform better when their con...
The prognostic value of systemic inflammatory indices in elderly patients with spontaneous intracerebral hemorrhage
Background Very old patients represent the fastest-growing age subgroup among patients with intracerebral hemorrhage (ICH), which justifies studying age-specific prognostic behavio...
Prevalence and risk factors of abuse against older adult women: A cross-sectional community study in Eastern Andalusia, Spain
Abuse against older adult women remains a serious public health issue and a flagrant violation of human rights in Spain. However, research specifically addressing abuse against older adult women is st...
Trends in admission, resource use and outcomes among elderly patients admitted to an intensive care unit in China
Background Population aging, coupled with improvements in healthcare, may influence ICU admission trends and care practices among critically ill elderly patients (≥80 years), longi...
Content-qualified antenatal care coverage in Lesotho: An ordinal logistic regression analysis of the 2023–2024 demographic and health survey
Background Despite high antenatal care contact coverage in Lesotho, the content and quality of care remains suboptimal. This study assessed the level and determinants of content-qu...
Overexpression of key complement regulators in glioblastoma
Background Glioblastoma (GBM) is the most prevalent and malignant primary brain tumor in adults. While immune evasion is a well-recognized driver of GBM progression and a major obs...
Multivariate control based on recurrent wavelet neural network for wastewater treatment process
The wastewater treatment process (WWTP), including multiple biochemical reactions, is a coupled and dynamic process. Thus, it is a challenge to achieve precise control of the WWTP. In order to address...
Effect of intra-dialytic pedaling exercise on dialysis adequacy: A randomized controlled trial
Background In patients with chronic kidney disease undergoing hemodialysis, physical activity and rehabilitation are crucial for preventing declines in muscle strength and function...
Monocrystalline silicon solar cell efficiency dependence on potassium silicate additive in texturing process with a study on the effect of the active material
Texturing is a critical process for enhancing monocrystalline silicon solar cell efficiency by reducing surface reflectance and improving light absorption. This study investigates the effect of introd...
An exploratory study on cortical hemodynamics and handgrip strength phenotypes in long-term hospitalized patients with stable schizophrenia
Objective This exploratory study aims to investigate the relationship between handgrip strength (HGS) phenotypes and cortical hemodynamics in long-term hospitalized patients with s...
Andean agriculture and hand tools: A qualitative approach of exploration of needs, barriers, and opportunities for innovation
Peruvian Andean agriculture primarily consists of subsistence activities that rely on traditional methods. Rural farmers use locally made hand tools, often designed without technical or ergonomic cons...
Investigating a potential association between agenesis of the third molars and variations in dental crown dimensions
The aim of this study was to investigate the association between third molar agenesis and mesiodistal crown dimensions in individuals from Germany. The sample consisted of 314 (156 males and 158 femal...
Age and language experience modulate predictive processing in the visual modality
Human language processing relies on the brain’s ability to predict structured input rapidly in time. While predictive coding has been widely studied in auditory language users, less is known about how...
Exploring nocturnal soundscapes in an Australian open forest system using acoustic indices
Nocturnal environments and their ecology remain noticeably under-represented in the scientific literature, despite their ecological importance, largely due to the practical challenges of sampling nigh...
Cultural factors in mid- and later life volunteerism in the United States: A scoping review protocol
Introduction Volunteerism in midlife and later life is linked to improved well-being for individuals and stronger communities, but participation rates differ widely across groups....
In vivo evaluation of binder jet 3D-Printed monetite, brushite, and octacalcium phosphate: A comparative study for bone regeneration in a rat calvarial defect model
Background Three-dimensional (3D)-printed hydroxyapatite (3DP-HA), fabricated via binder jetting of calcium sulfate-based powders followed by phase conversio...
Social factors related to the quality of life among older adults in southwestern Poland
Background The quality of life of older adults is closely linked to functioning in the living environment. This study aims to assess the quality of life of older adults in southwes...
Trauma-informed care for everyone: A study on patient and provider perspectives in an urban primary care setting
Background The importance of trauma-informed care is increasingly acknowledged as essential to generating a trusted relationship and safe environment in which to mitigate harms or...
Towards sustainable pharmacy practice: Community pharmacists’ experiences with medicine waste, reuse and disposal
Objective To explore the perspectives and experiences of community pharmacists in Northern Ireland regarding returned medicines, pharmaceutical waste, and safe disposal practices,...
Integrated effects of land cover, topography, urban morphology, and PM2.5 on land surface temperature
Rapid urbanization profoundly alters land surface characteristics, intensifying thermal stress and air pollution, yet the seasonal dynamics of land surface temperature (LST) in high-altitude cities re...
Chrysoprase color grading with machine learning: A systematic approach
The color of gemstones plays a pivotal role in determining their quality and significantly impacts their market value. However, inconsistencies in gemstone color evaluation, stemming from the subjecti...