PLoS ONE
Articles in this Issue
Editorial Note: Systematic multiscale models to predict the compressive strength of fly ash-based geopolymer concrete at various mixture proportions and curing regimes
Axolotl mandible regeneration following complete transverse amputation involves a blastema formation and exhibits a limit along the proximodistal axis
Current therapeutic strategies aimed at promoting the regeneration of craniofacial tissues do not fully address all physiological and aesthetic needs. This highlights the need to investigate the regen...
BaEV-pseudotyped lentiviral vectors enable stable CAR expression and cytotoxic function in NK cells
Lentiviral vectors (LVs) pseudotyped with either vesicular stomatitis virus glycoprotein (VSV-G) or baboon envelope glycoprotein (BaEV) have been studied for chimeric antigen receptor (CAR) transducti...
Adolescent sexual and reproductive health literacy in Saudi Arabia: The roles of school type and maternal education
Background Adolescent sexual and reproductive health (SRH) literacy remains uneven in conservative settings. We assessed SRH knowledge among female secondary-school students in Al-...
Priming iTBS for lower limb rehabilitation after stroke: Protocol for a randomized controlled trial on efficacy and neuroplasticity
Introduction Repetitive transcranial magnetic stimulation (rTMS) is widely applied in treating motor dysfunction after stroke. Building on metaplasticity principle, continuous thet...
Time-dependent changes in stepping performance and velocity following partial dopaminergic lesions in the SNc of male and female rats
Parkinson’s disease (PD) is a neurodegenerative disorder in which gait disturbances are a major source of disability, yet their early manifestations remain difficult to characterize because prodromal...
USMLE Step 2 Clinical Knowledge performance by disability, race, and ethnicity in U.S. medical students: A multi-site study
Importance With the transition of USMLE Step 1 to pass/fail, USMLE Step 2 Clinical Knowledge (CK) has become a high-stakes component of residency selection. This shift raises conce...
The importance of baseline health in linking life purpose to longevity
The well-established inverse relation between purpose in life and mortality risk is widely interpreted in the literature as evidence that higher purpose causes greater longevity. This study assesses t...
Comprehensive quantum chemical analysis, vibrational spectroscopy, molecular docking, ADMET, and in vitro validation studies of hydroxychloroquine-MRGPRX2 complex in IDH-wildtype glioblastoma
Glioblastoma is an aggressive astrocytic neoplasm characterized by significant intratumoral heterogeneity and resistance to standard therapies. Despite advances such as the Stupp protocol, the prognos...
Heavy metal footprints in landfill-proximate soils of Jashore, Bangladesh: An index-based risk assessment
Disposal of the household originated and industrial hazardous materials with municipal solid waste (MSW) into the open dumping sites is the usual practice in Bangladesh which raises concerns regarding...
Editorial Note: Ultra-compact quintuple-band terahertz metamaterial biosensor for enhanced blood cancer diagnostics
Editorial Note: A study of blockchain-based liquidity cross-chain model
GDT-SwinKid: A hybrid model for precise renal lesion analysis
Detecting and delineating renal lesions accurately remains a significant clinical problem due to the variety of kidney pathology and subtle differences in CT image interpretation. In this paper, we pr...
Long-term adherence to adapted physical activity in patients with chronic inflammatory arthritis: Insights from a longitudinal observational study
Adapted physical activity is recommended as a non-pharmacological strategy for the management of chronic inflammatory arthritis. However, the long-term adherence of patients to physical activity progr...
How climate change shapes global systemic risk transmission: A complex network approach
This study investigates the dynamic impact of climate change performance on extreme tail risk transmission across global financial markets. Based on the “Too Extreme to Fail” conceptual framework, we...
Evidence for mirror self-recognition in beluga whales (Delphinapterus leucas)
Tests of mirror self-recognition (MSR) have provided behavioral evidence of a high level of self-awareness in humans, chimpanzees, bonobos, orangutans, gorillas, bottlenose dolphins, Asian elephants,...
Prediabetes, diabetes, and the risk of progression to diabetes among working population in Beijing-the Tongren HealthCare Study
Introduction Our retrospective cohort study (3–9 years) describes the progression and regression patterns among working adults aged 18–65 with normoglycemia, prediabetes, and diabe...
Abscisic acid positively regulates rice spikelet closure
To investigate the mechanisms underlying rice glume closure and develop effective regulatory strategies, we examined both fertile (Xingan Zaozhan, Jiazao 70, and Zhenshan 97B) and sterile (Qiyuan S, Y...
Modeling cell migratory persistence through temporal correlations and angular noise
The persistence of cell migration is a fundamental property of motile behavior, enabling cells to maintain directionality while adapting to fluctuations and external cues. This feature underlies essen...
Skeletons in the permafrost: Exploring climate-driven heritage loss and occupational health at the early modern whaling burial site of Likneset, Svalbard
Rapid Arctic warming is accelerating the degradation of permafrost-preserved archaeological sites, threatening both cultural heritage and the scientific information it contains. Early modern whaling b...
Cave morphology and human-mediated sediment deposition: Late Pleistocene to Holocene evolution of the cave floor at Panga ya Saidi, coastal Kenya
Panga ya Saidi (PYS), a cave situated in a forested upland near the coast of Kenya, contains an archaeological record that spans at least 78,000 years and is crucial for understanding the evolution of...
Partial fishmeal replacement with poultry by-product meal and yeast enhances growth and health in Clarias gariepinus, while unbalanced PBM diets induce metabolic stress
This study evaluates a dual dietary strategy in African catfish ( Clarias gariepinus ): optimizing fishmeal replacement and assessing unbalanced, low-cost feedi...
Impact of axial length correction in high intraocular pressure eyes on intraocular lens power calculation
Purpose This study aimed to investigate the relationship between high intraocular pressure (IOP) effect on axial length (AL) and postoperative refractive error after cataract surge...
Head-driven gender assignment in noun-noun compound recognition: Evidence from a determiner priming task in German
A visual lexical decision task with noun-noun compound targets (e.g., Wasserflasche [waterbottle]) and gender-marked determiner primes (der, die, das [the] for...