PLoS ONE
Articles in this Issue
Comparison of dose-adjusted EPOCH-R and R-CHOP in diffuse large B-cell lymphoma with high Ki67 expression: Results from a prospective observational study
Objectives To compare the safety and efficacy of first-line dose-adjusted EPOCH-R (DA-EPOCH-R) versus R-CHOP treatment in diffuse large B-cell lymphoma (DLBCL) patients with high K...
Association between mobile phone use and risk of rheumatoid arthritis: A large prospective cohort study
Background It remains uncertain whether there is a relationship between mobile phone use and rheumatoid arthritis (RA). Research on the relationship between different mobile phone...
Between-session reliability and sensitivity of force production characteristics across various force-time points during the isometric single-leg long-lever bridge
The purpose of this study was to assess the between-session reliability of peak force and early force-time variables in a unilateral isometric hamstring assessment (isometric long-lever bridge). The s...
Arabic translation and psychometric validation of the Problem-Solving Decision-Making scale: A cross-sectional study in Saudi Arabia
The Problem-Solving Decision-Making scale was originally developed in English to assess patient preferences across three domains: mortality, morbidity, and quality of life. This study aimed to transla...
Rapid detection of Kenyan tomato leaf curl virus isolates using probe-enhanced loop-mediated isothermal amplification coupled with a modified DNA extraction method
Plant disease management requires sensitive and user-friendly diagnostic methods. The polymerase chain reaction (PCR) and other methods have helped diagnose diseases, but they are primarily used in hi...
A hybrid BiLSTM and rule-based system for integrated diabetes prediction and personalized guidance
Diabetes is a common chronic disease that needs early diagnosis and proper management to avoid severe complications. While current Artificial Intelligence (AI) tools generate predictive information, t...
Community pharmacy-led diabetes management using continuous glucose monitoring for suboptimally controlled type 2 diabetes: A pilot feasibility study
Many adults with type 2 diabetes mellitus (T2DM) managed without insulin continue to experience suboptimally controlled glycemia. This 12-week, single-arm pilot feasibility study was conducted across...
Dynamic adjustment algorithm of equipment maintenance cycle based on substation state operation and maintenance
To improve the timeliness and effectiveness of equipment maintenance and ensure the stable operation of power systems, this paper proposes a dynamic adjustment algorithm for equipment maintenance cycl...
Exploring drivers and management strategies of informal patient payments in hospitals: A qualitative study in Iran
Background Informal patient payments remain a persistent and multifaceted challenge in many health systems, particularly in low- and middle-income countries. These payments, often...
Coverage of insecticide-treated mosquito nets in preschool consultations and factors associated with non-use of insecticide-treated mosquito nets among children in the Democratic Republic of Congo: A base population cross-sectional study
Insecticide-treated nets (ITNs) are among the most effective malaria prevention interventions, yet their actual use among children remains below national targets. This study assesses ITN coverage and...
OracleTrust: A dual-layer provenance-based signature verification scheme for preventing transaction malleability in blockchain
Decentralized oracle networks pose significant security risks to blockchain systems due to transaction malleability, which can lead to double-spending and integrity issues. While existing solutions su...
Correction: Impact of skin tone, environmental, and technical factors on thermal imaging
Timely Integration of specialist palliative care into oncology care for patients receiving radiotherapy for bone metastases: A study procotol for the TIPZO-RT Randomized Controlled Trial
Background Patients living with advanced cancer often benefit from palliative care. Timely referral to specialist palliative care improves quality of life and reduces potentially i...
Association between different atherogenic and insulin resistance indices and infertility in polycystic ovary syndrome patients
Background This study aimed to assess the association between multiple atherogenic and insulin resistance indices—including TyG, TyG-BMI, AIP, TG-HDL, and METS-IR—and infertility i...
Correction: Pahon Cave, Gabon: New insights into the Later Stone Age in the African rainforest
Prevalence and determinants of workplace violence among nurses in public tertiary hospitals in Enugu state, Nigeria
Background Despite its impact on nurses’ well-being, hospital efficiency, and patients’ quality of care, published studies on workplace violence against nurses in sub-Saharan Afric...
Enhanced accuracy and adaptability: An ISSA-optimized MPC approach for AGV trajectory tracking
To enhance the tracking accuracy of AGVs, this paper proposes an online adaptive optimization strategy for MPC weight parameters based on the Improved Sparrow Search Algorithm (ISSA). Firstly, the kin...
Comparative analysis of seven types of phosphate transporters in forty species from the phylogenetic and transcriptomic perspective
Acquisition of phosphorus (P), an essential macronutrient for plants, is a limiting factor in most soils. Phosphate transporter proteins (PTs) play an indispensable role in inorganic phosphate (Pi) tr...
Double-cuff versus single-cuff bronchial blockers for video-assisted thoracoscopic lobectomy: A randomized controlled trial
Background Bronchial blockers (BBs) manage airways during thoracoscopic lobectomy and isolate lungs by occluding the bronchus at the surgical site. However, intraoperative malposit...
The inhibitors of miR-224-5p, miR-339-5p, and miR-1198-5p improve auditory function by promoting the expression of neuritin in hearing loss mice
Background Sensorineural hearing loss (SNHL) is the main type of hearing impairment, and currently there is a lack of effective preventive or therapeutic drugs. Our previous resear...
ADVANTAGE: Advanced discovery of visceral analgesics by neuroimmune targets and the genetics of extreme human phenotype, a study protocol
Chronic visceral pain affects over 20% of adults globally but remains poorly understood, significantly impacting quality of life and healthcare costs. Limited understanding and diagnostic misconceptio...
Disparities in prostate cancer screening practices among general practitioners and urologists (PROSHADE study): A cross-sectional study
Introduction Recent European recommendations promote risk-based, patient-centred screening models that emphasise shared decision-making (SDM) in prostate cancer (PCa) screening wit...
Development of a protocol for intravenous infusion management in patients with aggressive behavior due to mental disorders: A Donabedian framework approach
To establish a scientifically grounded and feasible intravenous infusion management protocol for patients with Aggressive behavior due to mental disorders. Methods: Guided by Donabedian’s theory, an i...
Identifying and validating ITGB2 and HNRNPAB as diagnostic biomarkers in chronic obstructive pulmonary disease using bioinformatics and Integrated Machine Learning Methods
Background and Aim COPD is a common respiratory disease characterized by progressive airflow restriction that severely affects patients’ quality of life and leads to significant mo...
‘Just Play’ (JP) - creative arts therapies-based dyadic intervention for children with intellectual disability and their mothers: Study protocol for a mixed-methods randomized controlled trial
Background Play is a fundamental aspect of children’s development, fostering their cognitive, social, and emotional growth. However, children with intellectual disability (ID) expe...