PLoS ONE
Articles in this Issue
PEG-fusion of viable sciatic nerve isografts restores axonal structure and behavioral recovery after segmental-loss sciatic nerve injuries in Lewis rats
Segmental-loss peripheral nerve injuries (SL-PNIs) often produce severe deficits in sensory/motor functions and voluntary behaviors. The current gold standard for repair is neurorrhaphy of a cable aut...
Impact of cardiometabolic index on long-term mortality in young adults with type 2 diabetes mellitus
Background The cardiometabolic index (CMI) has been utilized in recent years to detect patients with type 2 diabetes mellitus (T2DM). Given the consistent annual rise in the incide...
Enhancing aviation safety: An 80-year data-driven model for classification of aviation incident and accident
The aviation system is safety-critical by nature, and any occurrence of an incident or accident can lead to the loss of human life and significant operational disruptions. The International Civil Avia...
Evaluating the Integrated Disease Surveillance and Response system in Sidama Region, Ethiopia: A systems evaluation
Background Integrated Disease Surveillance and Response (IDSR) systems play a vital role in early detection and response to public health threats. In Ethiopia, limited evaluations...
Decoding the genetic basis of demyelination: Prediction of potential pathogenic coding and regulatory noncoding MBP SNPs in multiple sclerosis
Background The Myelin Basic Protein (MBP) gene is essential for myelin sheath formation in the central nervous system. Coding and noncoding single-nucleotide...
Effects of compartment and severity of pelvic organ prolapse on voiding difficulty and overactive bladder: A case-control study with multiple outcomes
Background The current understanding of the relationship between different degrees of prolapse and the impact of prolapse in different compartments on voiding difficulty (VD) and o...
Medication error reporting in Ghana: A multicenter assessment of healthcare professionals’ knowledge, attitudes and practices
Background Medication errors (MEs) remain a leading cause of preventable patient harm globally, with significant implications in low- and middle-income countries (LMICs) where repo...
A systematic review and narrative synthesis of the psychometric properties and biopsychosocial correlates of the English version of the Intuitive Eating Scale-2
Intuitive eating is an adaptive eating approach characterised by having unconditional permission to eat when you are hungry, eating for physical rather than emotional reasons, relying on internal hung...
Prediction of cognitive impairment through speech data analysis: A comparative evaluation of deep learning models
Background The early detection of cognitive impairments, such as mild cognitive impairment (MCI) and Alzheimer’s disease (AD), is essential for timely intervention and management....
Views of the Swiss public towards gene editing
There is little country-specific data about how the general public views gene editing therapies. In Autumn 2023 we randomly surveyed the Swiss public, using the Federal Register and stratifying by lan...
Editorial Note: Home bias and employee social responsibility: Identification vs. benefit exchange
Incidence of frailty-related fracture among Medicaid beneficiaries living with HIV and cancer: A cohort study
Background People living with HIV (PLWH) are at increased risk for frailty-related fracture. Limited evidence suggests recent diagnosis of non-AIDS defining cancer (NADC) is a risk...
Endophyte diversity and its correlation with naphthoquinone metabolites in cultivated Arnebia euchroma across different growth years
Previous studies on Arnebia euchroma (Royle) Johnst. have focused on its physicochemical and pharmacological properties, and studies on the differences in metab...
Investigating the application value of the “Forward-Deployed Position” model in operating room support by the central sterile supply department
Objective To investigate the application effects of the “Forward-Deployed Position” model in operating room support provided by the Central Sterile Supply Department (CSSD)....
A collaborative approach to applying Natural Language Processing (NLP) to Domestic Homicide Reviews (DHRs): A study protocol
Since 2011, there has been a statutory requirement in England and Wales to conduct a Domestic Homicide Review (DHR) into any domestic abuse-related death: a multi-agency review into the death of a per...
Developmental transition of visual and nonvisual photoreception and circadian clock during smoltification in the eye and brain of Atlantic salmon
Seasonal variation in photoperiod is an important cue that regulates changes in physiology and behavior during the anadromous lifestyle of Atlantic salmon. The parr-smolt transformation or smoltificat...
Dietary cholesterol reduces blood pressure and alters lipid profiles in stroke-prone spontaneously hypertensive rats
Although cholesterol (Chol) is widely recognized as a risk factor for cardiovascular disease, dietary Chol intake has been reported to extend the lifespan of stroke-prone spontaneously hypertensive ra...
Eigen-guided transformer: A data-driven approach for chronic kidney disease forecasting
Accurate prediction of Chronic Kidney Disease (CKD) development is essential for prompt therapeutic intervention; nevertheless, it is difficult due to the highly individualized disease trajectories an...
Getting psychiatry on the move—Implementation and evaluation of Braining, a structured physical exercise intervention in outpatient psychiatry: A convergent-parallel mixed methods study
Background Physical exercise can improve mental health outcomes, yet patients with mental illness often require structured support. Braining is a 12-week structured physical exerci...
Spiritual leadership and service performance among Chinese flight attendants: The mediating effects of meaningful work and work engagement
As indispensable members of the flight crew for passenger transport on large aircraft, flight attendants are responsible for cabin safety, security, passenger services, and emergency response during f...
The epidemiology of SARS-CoV-2, Influenza, and Respiratory Syncytial Virus circulation among adult patients with acute respiratory illness in Kampala Metropolitan Area in Uganda
Background Acute respiratory infections (ARI) caused by viruses such as SARS-CoV-2, influenza, and respiratory syncytial virus (RSV) posed significant public health challenges, par...
Comparison between two different concentrations of ropivacaine in pericapsular nerve group block for patients undergoing total hip arthroplasty: A randomized clinical trial
Effective pain control during spinal anesthesia positioning remains a clinical challenge in elderly patients undergoing total hip arthroplasty. The pericapsular nerve group block, a novel ultrasound-g...
Knowledge, attitudes, and practices related to adult vaccination among adults and healthcare professionals across Mexico
Background Despite substantial evidence supporting the benefits of vaccination across all age groups, achieving high vaccine coverage in adults remains a global challenge. Limited...
Characterizing the myeloid and lymphoid immune response in a porcine model of pulmonary ischemia-reperfusion injury through flow cytometry
Pulmonary ischemia-reperfusion injury (IRI) is a major cause of primary graft dysfunction in lung transplantation. Porcine models better simulate physiological conditions and are important for pre-cli...
Analysis of the relationship between body mass index and kidney function decline in a middle-aged Japanese population: A population-based retrospective cohort study
Japan has one of the highest dialysis prevalence rates worldwide, resulting in substantial economic and health burdens. Although obesity is a known risk factor for the decline of kidney function, the...