PLoS ONE
Articles in this Issue
Views, barriers, and facilitators of people living with human immunodeficiency virus and healthcare professionals regarding the use of a mobile health application to improve HIV self-care in Malaysia
Aim The views, barriers, and facilitators of people living with HIV (PLWH) and healthcare professionals (HCPs), regarding the use of a mobile health application (m-HA) to improve H...
S-palmitoylation regulates the function of the mitochondria-associated endoplasmic reticulum membrane to alleviate the senescence of nucleus pulposus cells
Intervertebral disc degeneration (IVDD) is the primary cause of spinal degenerative diseases. Nucleus pulposus (NP) cell senescence is a significant pathological manifestation of IVDD. Here, we constr...
LeafDet: A lightweight and interpretable deep learning framework for tomato leaf disease detection
Ensuring global food security depends on timely and reliable plant disease identification. Traditional disease detection methods often prove inefficient because of the lack of necessary precision. Fur...
Correction: Phytochemical profiling of Vitex negundo seeds via UHPLC-QTOF-MS/MS analyses with antimicrobial evaluation and in silico targeting of DNA Gyrase B and Secreted Aspartic Proteinase 2 (SAP2)
TDD-YOLO: A novel model for precise detection of tomato diseases
Tomato diseases pose a significant threat to global agricultural production, often leading to substantial yield loss and major economic damage. Traditional disease detection methods rely on manual ins...
A qualitative study to inform the design and implementation of AI-driven diagnosis: Challenges, barriers, and clinical insights of physicians
Introduction Acute febrile illnesses are significant clinical challenge in tropical regions due to overlapping symptomatology among infections such as dengue, scrub typhus, and lep...
Differential game in closed-loop supply chain of innovative products with double regrets of consumers
In this paper, we consider a three-level dynamic closed-loop supply chain differential game model led by manufacturers and recycled by third-party recyclers in order to study the impact on the dynamic...
High donor hemoglobin interacts with pre-transplant recipient neutropenia to modulate mortality after allogeneic hematopoietic stem cell transplantation: An exploratory, single-center, retrospective, real-world study
Prognostication after allogeneic hematopoietic stem cell transplantation remains a critical challenge, and the complex interplay between recipient vulnerability and donor graft characteristics is poor...
Crisis leadership and strategic decisions in Swedish maternity care during the COVID-19 pandemic: A deductive analysis from the COPE staff project
Background Healthcare managers played a crucial role during the COVID-19 pandemic, tasked with organizing care for a new medical condition, implementing restrictions to reduce infe...
Range-weighted branch length difference (RWiBaLD), a new method for distinguishing meso-endemism from neo-endemism and paleo-endemism
Our goal is to enhance understanding of phylogenetic endemism (PE), which is studied using a range-weighted phylogenetic tree. We present a new method called...
Distinct early-life mechanisms of quantity discrimination in domestic chicks
In research on animal numerical cognition, newly hatched domestic chicks have been shown to rely on distinct strategies when confronted with quantitative choices. In some conditions, such as after imp...
Trajectory planning method for pipeline installation robots based on AS-DTRRT
Pipeline installation robots install pipelines on both sides of mine roadways using robotic arms; the geometric shape and length of the pipelines affect the movement trajectory of the robotic arms, an...
Retraction: SPAG6 hypermethylation silences a novel tumor suppressor and inhibits renal cell carcinoma progression via PI3K/AKT/mTOR pathway
Characteristics of Escherichia coli ST131 strains isolated from dogs and cats with urinary tract infections in a teaching hospital in Taiwan
Escherichia coli sequence type (ST) 131 is a globally disseminated multidrug-resistant clone that poses a substantial public health threat. This study investigated the prevalence,...
Restrictive versus liberal oxygenation targets in patients with acute heart failure and pulmonary congestion–A protocol for a Randomized Controlled Trial (The REDOX-AHF trial)
Introduction Acute heart failure (AHF) is the cause of one in twenty hospital admissions. Supplemental oxygen therapy is a routine treatment in the managemen...
Vitamin D alleviates neurotoxicity induced by propofol anaesthesia in the offspring of mice
Background Maternal propofol can induce neurotoxicity in the developing brain. Vitamin D modulates neurotrophin and neuromediator synthesis, reduces neuroinflammation and neuroapop...
Ovarian follicle dynamics in the plains zebra (Equus quagga)
Understanding follicular dynamics during the estrous cycle is essential for developing breeding programs and assisted reproductive technologies (ARTs) in any species. In this context, knowledge of fol...
RAGER: A user-friendly computational platform for integrated analysis of RNA-Seq and ATAC-seq data
Technical advances in RNA sequencing (RNA-seq) and Assay for Transposase-Accessible Chromatin sequencing (ATAC-seq) provide us a genome-wide method to deeper insights into gene expression and regulati...
C–N exchange model of legume–Rhizobium symbiosis incorporating ATP budget constraints and energy–mass balance between the species
We present a comparative advantage model of carbon–nitrogen exchange in legume– Rhizobium symbiosis that incorporates ATP budget constraints and the energy–mass...
The effect of Demodex-associated Bacillus oleronius proteins and hyperosmolarity on a human conjunctival epithelial cell line
Purpose Demodex mites act as a carrier vector for the bacterium Bacillus oleronius . Antigenic proteins from this...
28-day all-cause mortality and associated factors in cancer patients with bacteremia at a peruvian referral center
Introduction The global prevalence of cancer has increased in recent decades. Cancer patients are especially vulnerable to invasive infections like bacteremia. In Peru, the rising...
Peer-mediated instruction improves acquisition of complex wrestling techniques in school physical education
This study investigated the effectiveness of peer-mediated instruction as a student-centered teaching method in physical education by assessing its impact on middle school students’ ability to learn c...
Retinal macrophage-like cell activation and ganglion cell layer thinning are associated with disability and MRI lesion burden in multiple sclerosis
Background Multiple sclerosis is a chronic neuroinflammatory disease in which microglia and macrophage-like cells play a central role in disease progression. The retina, as a centr...
Effectiveness of tele-rehabilitation using AI-guided exercise and pain neuroscience education for fibromyalgia (FIBROIA): Protocol for a randomized controlled trial
Introduction Fibromyalgia (FM) is a chronic condition characterized by widespread pain and cognitive dysfunction, with pharmacological treatments offering limited efficacy. Althoug...
Assessment of agricultural region dynamics using object contour properties from Sentinel-2 images
Economic activity in agricultural regions is influenced by various natural and anthropogenic factors. Their impact on spatial and temporal changes can be assessed by studying satellite images acquired...