PLoS ONE
Articles in this Issue
The news media and the agenda for noncommunicable diseases before and during the COVID-19 pandemic: Losing the competition for coverage and framing responsibility for action in Malawi
Chronic noncommunicable diseases (NCDs, such as cardiovascular and diabetes) pose an increasing burden in low-and middle-income countries, accounting for ~80% of premature (under age 70) NCD deaths gl...
Co-occurrence of antibiotic residues and Antimicrobial resistance genes in animal manure and agricultural soils from Machakos, Kiambu, and Kajiado Counties, Kenya
The excessive and often unregulated use of antibiotics in livestock production and human health has led to the dissemination of antibiotic residues and antibiotic resistance genes (ARGs) posing a seri...
Viral replication dynamics: Coinfection and superinfection of Vero cells with Zika virus and West Nile virus or Zika virus and Mayaro virus
Globalization and climate change have contributed to the emergence and spread of arboviruses, with the possibility of their cocirculation in the same geographic region at the same time. Understanding...
Study protocol for a pilot evaluation of Talk With Me Baby (TWMB) for Well-Child Care: A primary care-integrated language promotion intervention in rural and underserved clinics
A child’s home language environment (HLE) refers to the quality of early language exposure and linguistic interactions with caregivers. A robust HLE is a primary public health consideration, as it pos...
G-protein coupled receptor, signal and signal-transduction related transcript mapping in nigral volume and pigmented neurons reveals a potential deficit of nigral feedback signals associated with Parkinson’s disease
Microarray and Next Generation Sequencing studies offer insight into gene regulation in Parkinson’s disease (PD). However, analysing vast numbers of genes can make the interpretation of data difficult...
Spatial-aware lightweight network for real-time tea disease detection: A coordinate attention-enhanced YOLOv8n approach with path-decoupling strategy
The intelligent identification of tea diseases is crucial for ensuring tea quality and reducing economic losses in the tea industry. However, the deployment of deep learning models on edge devices rem...
Robust point cloud lightweighting with multi-scale adaptive filtering and entropy-driven subdivision
Current point cloud simplification methods for complex ground objects face a persistent challenge: balancing noise robustness and geometric detail preservation. To resolve this, we present a lightweig...
When place and generation matter: Understanding resident satisfaction in rural tourism
The revitalization of traditional villages through rural tourism has emerged as an important pathway for achieving sustainable regional development worldwide. Although the benefits of tourism are wide...
Factors associated with severe acute respiratory syndrome coronavirus-2 infection in Hohoe Municipality, Ghana: A case-control study
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection was a major public health challenge globally and in Ghana. To prepare better for future pandemics, an evidence-based understandin...
Construction of a fine-grained retrieval model for archival text-image based on the integration of scene graph generation and attention mechanism
To tackle the challenges in fine-grained retrieval stemming from noise, official seal occlusions, small text blocks, and other issues prevalent in archival text images, and to fulfill the requirements...
Fundus image analysis of retinitis pigmentosa using artificial intelligence
Retinitis pigmentosa (RP) is a group of inherited retinal diseases that are caused by genetic defects that lead to progressive photoreceptor loss and eventual blindness. Early diagnosis would be helpf...
Clinical and microbiological epidemiology of Candida infections in a high-complexity hospital in Tolima, Colombia (2014–2024)
Background Candida spp. infections are an increasing challenge in high-complexity hospitals, yet epidemiological data remain scarce in...
Occupational interventions and their effects on work-related and mental health outcomes: A scoping review protocol
Background The well-being of individuals within their workplace (i.e., workplace mental health) has important implications for their productivity and mental health. The extensive l...
Bactericidal and anti-inflammatory activity of defined hypochlorite solution
Background Hypochlorite is an antiseptic that has been used for over a century for industrial sterilisation and antisepsis. More recently, the topical application of hypochlorite t...
Global and local impacts of multi-dimensional urban form on PM2.5 concentrations: A case study of the downstream urban agglomeration in the Yangtze River Delta
The acceleration of urbanization and the expansion of population scale have led to increasingly prominent PM2.5 pollution. Taking the urban agglomeration in the lower reaches of the Yangtze River with...
Breast cancer clustering integrating complete gene expression profiles and genetic ancestry
Breast cancer (BC) remains the leading cause of cancer-related mortality among women globally. Precise subtyping of BC is critical for optimizing treatment strategies. This study explored the capacity...
Quantitative assessment of synergistic effects in push-pull tactical ventilation during nonlinear space fires
Smoke generated in compartment fires rapidly degrades visibility and tenability, making mechanical tactical ventilation a critical measure for restoring operable conditions. This study provides a full...
The impact of Kamala Harris’s social identities during the 2024 presidential election
The social identities of Democratic Party presidential nominee Kamala Harris were noted frequently prior to the 2024 United States Election. We examined how making salient her marginalized racial and...
Association between high-density-lipoprotein cholesterol and postoperative recovery from lumbar disc herniation
Objective The levels of high density lipoprotein cholesterol (HDL-C) correlate with lumbar spine degeneration, but their value for predicting the prognosis of the lumbar spine is u...
Effects of light qualities on the growth and photosynthetic characteristics of Sorbus tianschanica Rupr. seedlings
Light quality is an important environmental factor influencing plant growth and development, but its effects on functional traits and physiological processes in woody seedlings remain unclear. In this...
Preoperative and perioperative factors that predict graft failure 1 year after Descemet membrane endothelial keratoplasty
Purpose To identify pre/perioperative factors that predict graft failure after Descemet membrane endothelial keratoplasty (DMEK)....
Patterns of inpatient antibiotic use and antimicrobial resistance in the surgical wards of a Ugandan tertiary hospital: A mixed methods study
Background Inappropriate antibiotic use in surgical wards is a major driver of antimicrobial resistance (AMR), especially in low- and middle-income countries, where empirical presc...
Revisiting the grammaticalization of future be going to: A corpus-based approach
Through the quantification of frequency, existing corpus-based quantitative studies on grammaticalization offer a new direction for empirical investigation. However, most existing studies focus on gen...
Ionospheric TEC anomalies analysis and prediction during six volcanic eruptions using a Hybrid ML-DL model and comparison with the AR/MLR Models
Eruption of volcanoes is associated with the emission of great energy through the propagation of atmospheric waves up into space. These waves cause significant disturbances in the ionosphere, a region...
A 3-dimensional Resnet model for assessment of drug efficacy in 3D cancer models using optical coherence tomography
Ninety percent of drugs fail during clinical trials, mainly due to lack of clinical efficacy. Recent developments in in vitro models such as 3D tumor heterosphe...