PLoS ONE
Articles in this Issue
Sleep satisfaction and problematic smartphone use among adolescents in the Republic of Korea: The mediating roles of anxiety and loneliness
Problematic smartphone use (PSU) has become a growing public health concern among adolescents, with global prevalence estimates ranging from 10% to 30%. Sleep dissatisfaction has been identified as a...
Unspoken cycles: A qualitative study exploring the lived experiences of women’s menstruation in the urban informal settlements of Bangladesh
Background Menstrual health and hygiene (MHH) is a critical component of public health and gender equity. However, limited research has explored the everyday experiences of women a...
Pattern of family dynamics and treatment-seeking behaviour of caregivers of under-five children with uncomplicated malaria in a tertiary hospital in Ilesa, southwestern Nigeria
Background The morbidity and possible consequent mortality resulting from malaria in children are either due to delayed treatment-seeking or preceded by an inappropriate treatment-...
Myocardial microvascular patterns in histological sections from patients with and without type 2 diabetes
Type 2 diabetes is associated with small vessels dysfunction. This study assessed whether type 2 diabetes is associated with changes in the myocardial capillary pattern in two-dimensional histological...
Machine learning–optimized discharge timing in typhoid care: Implications for clinical outcomes, cost efficiency, and health system performance
Objective To develop and validate a machine learning model identifying typhoid fever patients at risk of unnecessarily prolonged hospitalization, and to quantify the clinical, fina...
Urinary podocalyxin as an early biomarker for diabetic nephropathy
Background Conventional biomarkers, such as the urinary albumin-to-creatinine ratio (uACR), detect diabetic nephropathy (DN) late in its course and may miss early podocyte injury....
Expression of Concern: Molecular prevalence, phylogeny and hematological impact of Toxoplasma gondii and Plasmodium spp. in common quails from Punjab, Pakistan
Identification of Candidate epitopes from nation-enriched sequences in the African swine fever virus genomes
African swine fever virus (ASFV) is a highly lethal pathogen that causes African swine fever (ASF) and is found in Africa, Europe, and Asia. In addition, extensive regional genetic variation poses sig...
Towards a behavioral profile of degree adverbs in Mainland and Taiwan Mandarin news language
The major difference between Mainland Mandarin and Taiwan Mandarin in adverb usage lies in degree adverbs. Exploring the similarities and differences in degree adverbs across both sides of the strait...
Behavioural and emotional assessment of Malaysian adolescent boys with congenital colour vision deficiency and its association with socioeconomic factors
Congenital colour vision deficiency (CCVD) is associated with challenges in daily functioning and social interactions, yet its behavioural and emotional implications during adolescence remain underexp...
Integrated machine learning for cause-of-death classification and postmortem interval prediction: Liver and kidney metabolomics from seawater-immersed rat cadavers
Purpose To assess whether liver and kidney metabolomics combined with machine learning can distinguish seawater drowning from postmortem submersion after CO...
Single-cell transcriptomic analysis reveals the immunosuppressive status of NK cell subpopulations in TNBC
Triple-negative breast cancer (TNBC), lacking expression of the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2), has clinical features that incl...
Assessment of trends and determinants of under-five mortality among children born to older women: Evidence from Ethiopian demographic and health surveys
Introduction Under-five mortality has long been used as an indicator of the level of socio-economic development of a country. Global attention has been given to the issue through t...
Analysis of mechanical properties and micro-mechanisms of concrete based on the method of using steel slag as aggregate replacement: Macro-mechanical tests and microscopic tests of four typical control groups
There is still controversy over whether the mechanical properties of steel slag concrete are superior to those of ordinary crushed-stone concrete and which method of substituting steel slag for aggreg...
The impact of political ideologies on cultural erosion: Indigenous education policy in Brazil (2009–2022)
Indigenous schools in Brazil aim to provide equitable education to both Indigenous and non-Indigenous communities. As of 2022, there were 3,411 such schools operating nationwide, serving the entire In...
Optimal exercise modalities and dosages for improving depression in middle-aged and older adults with Parkinson's disease: A Bayesian Dose–response network meta-analysis
Objective To characterise the dose response relationship between exercise and depressive symptoms in middle aged and older adults with Parkinson disease using a continuous modellin...
Experimental and numerical studies on heat exchange between slag/metal particles and air inside countercurrent cyclone heat exchanger for recovering waste heat from molten slags in dry and centrifugal granulation process
In dry and centrifugal granulation of molten slags with heat recovery, the heat exchange efficiency between high-temperature particles and the cold air directly determines the efficiency of waste heat...
A novel approach for automated counting of tumor cell colonies
Background and Objective The heterogeneous response of cancer cells to radiation necessitates comprehensive investigations into cell survival, which are often conducted using clono...
Measurement of sludge-water interface based on adjustable peak point of ultrasonic echo energy
To address the escalating water resources consumption, the need for intelligent automation in urban sewage treatment has become imperative. However, existing ultrasonic sludge interface instruments ha...
The anxious society’s fertility problem: The promoting effect of physical exercise on mental health—An empirical analysis using CGSS data
The declining willingness to have children is significantly influenced by underlying psychological constraints that cannot be ignored. Providing psychological health support and interventions for the...
Biodiversity of Eucalyptus endophytic fungi across different climates in Iran
Endophytic fungi are crucial for plant health, but the relative importance of climate versus host factors in shaping their communities is not fully understood. This study investigates the hypothesis t...
Identifying academic success and underperformance: The discriminative power of very short answer questions and multiple-choice questions
Background Multiple-choice questions (MCQs) are widely used in medical education, but are criticized for cueing and guessing. Very short answer questions (VS...
Insomnia and psychological disintegration: Evidence from a transdiagnostic network analysis
Insomnia is commonly conceptualized in terms of hyperarousal or symptom amplification; however, less attention has been paid to the structural organization and integration of psychological processes u...
The current status of health literacy among caregivers of lung cancer patients:A cross-sectional survey
Aim This exploratory, hypothesis-generating study aimed to investigate the current status of cancer health literacy among lung cancer caregivers and to identify factors associated...
Direct medical costs of respiratory infections in adults: A multicenter retrospective analysis in Thai Nguyen, Vietnam
Background Respiratory infections remain a significant health and economic burden in low- and middle-income countries, including Vietnam. This study aimed to estimate the direct me...