PLoS ONE
Articles in this Issue
Development and validation of a photogrammetry-based preoperative method (BREAST-E) for quantitative breast morphometric analysis and volume estimation of breast in reconstructive surgery
Background The demand for reproducible, reliable, and cost-effective tools regarding preoperative breast surgery planning is significant in low- and middle-income countries (LMICs)...
Myasthenia gravis: Diagnostic journey and therapeutic outcomes in patients followed at a Brazilian public tertiary center — A retrospective cohort study
Background Myasthenia gravis (MG) is a heterogeneous autoimmune disorder of the neuromuscular junction. Diagnosis and management remain challenging in real-world settings, particul...
Cost analysis of a sequential antimicrobial therapy protocol in patients with pneumonia: A multicenter study
Pneumonia is one of the leading causes of hospitalization and mortality due to infectious diseases and is also responsible for a substantial proportion of antimicrobial prescriptions. This study aimed...
Intentional incisions on Neolithic Obsidian arrowheads from Central Anatolia: A techno-functional and iconographic approach
Incised obsidian arrowheads form a rare and geographically restricted artifact class, known exclusively from Neolithic Central Anatolia between the late 8th and 7th millennia BCE. These artifacts, mar...
Factors affecting lung cancer stage at diagnosis and receipt of surgery in Ontario: A population-based analysis
Lung cancer is the leading cause of cancer mortality in Canada, with most cases diagnosed at advanced stage. Despite universal healthcare, social determinants of health may impact stage at diagnosis a...
Preoperative anxiety: Is it affected by preoperative counseling and surgical technique?
Background Preoperative anxiety (PA) is a common psychological response that can adversely affect patient satisfaction and surgical complications and outcomes. To reduce these effe...
Beyond speed and strategy: A configurational analysis of collective attention to post-match institutional discourse in the UEFA Champions League
Post-match institutional communication has become a visible component of elite football events, yet comparable official messages can receive very different levels of public attention. This study exami...
Distribution and efficacy of ingested dsRNA targeting tissue-specific genes in the Argentine ant, Linepithema humile
With the increasing availability of genomic and transcriptomic information within Formicidae, the investigation of gene function has become possible within ants. However, eusocial life history renders...
Glutamate administration is associated with aggravated atherosclerosis and altered expression of RAPGEF1, OPN, and MYL7 in High-Fat Diet-Fed ApoE⁻/⁻ Mice
Objective This study aims to examine whether oral glutamate administration is associated with accelerated atherosclerosis progression in high-fat diet-fed ApoE ⁻ / ⁻ mice and to id...
Contemporary patients with atrial fibrillation are not anticoagulated despite risks of stroke - Insights from GARDENIA
Background GARDENIA is a global, multicentre, prospective, non-interventional study in high-risk atrial fibrillation (AF) patients, who were untreated with anticoagulants....
The mediating role of organizational justice in the relationship between value-centered school culture and organizational citizenship: A case of North Cyprus
This quantitative research aimed to determine the mediating role of organizational justice in the relationship between teachers’ perceptions of value-centered school culture and their views on organiz...
Spillover effects on infant caregiving and domestic work during the poriborton clean cookstove trial
Quality care during early childhood is essential for life-long health, well-being, and productivity. Recognizing the global importance of advancing early childhood development strategies, this study c...
Beyond physical fitness: Pre-to-post hematological and physical fitness changes during an eight-week multi-component exercise program in sedentary adults aged 30–45 years
This exploratory study aimed to examine pre-to-post changes in physical fitness and selected hematological parameters during an 8-week multi-component exercise program in sedentary adults. The study u...
Design of a novel epitope-based tetravalent subunit vaccine against dengue virus: An immunoinformatic approach
Dengue imposes a profound global impact, with millions affected annually. Its transmission by Aedes mosquitoes poses significant challenges to combat, aggravate...
‘Pilot RCT of a new treatment for child conduct problems that have not responded to evidence-based parent training’
Background Children with conduct problems are at high risk of persisting mental health problems, making them a priority for early intervention. Group-based parent-training is effec...
Stability of grain and fodder yields in extra-early cowpea genotypes in Southeastern Niger
Cowpea [ Vigna unguiculata (L.) Walp.] is a vital food and fodder crop in Niger, but its productivity is constrained by drought, poor soils, striga and pest pre...
Correction: The relationship between N-terminal pro-brain natriuretic and coronary artery lesions in Kawasaki disease: A meta-analysis
Correction: Burnout among anesthesia personnel in Thailand: A national survey of workload, personality traits, and resilience
Analysis of physical and physiological training demands in women’s basketball
Purpose The primary aim of the present study was to analyze the physical and physiological demands associated with different training tasks in women’s basketball....
Artificial intelligence for early detection of diabetic retinopathy: A vision transformer-based approach
Background Early identification of diabetic retinopathy (DR), which is a primary cause of vision impairment globally, is a crucial phasis for effective intervention and treatment....
Persistence of viable opportunistic pathogens in a multi-stage natural wastewater treatment system
Nature-based wastewater treatment systems are increasingly implemented to support water reuse in arid regions, yet their effectiveness in removing viable culturable opportunistic pathogens remains ins...
Dual regulatory effects of medical bovine collagen sponge on macrophages in vitro
Medical bovine collagen sponges (MBCS) are extensively utilized in clinical settings for hemostasis and tissue augmentation owing to their superior biocompatibility, biodegradability and hemostatic pr...
The effect of squat training with different eccentric contraction tempos on lower limb muscle strength
Objective This study aims to investigate the impact of 8-week squat training with different eccentric contraction tempos on maximal squat strength, jump height, and sprint performa...
Public parks utilization and citizen satisfaction in Bangkok Metropolitan: An integrated theoretical model for tropical urban health
Background Tropical megacities face escalating non-communicable disease burdens requiring innovative urban health solutions. Despite public parks’ critical role as health infrastru...
A simulation model to predict the most efficient way to utilise operational resources when vaccinating badgers against bTB
Bovine tuberculosis (bTB) is a disease carried by badgers that seriously impacts the health and productivity of cattle in the United Kingdom (UK). The UK government’s aim is to be officially TB-free i...