PLoS ONE
Articles in this Issue
Modified Roux-en-Y gastric bypass surgery avoids complications in mice
Background Roux-en-Y gastric bypass（RYGB）surgery delivers an improvement in obesity and obesity-related risks. However, due to the limited operational space in the abdominal cavity of mice, the tech...
Autoencoder techniques for survival analysis on renal cell carcinoma
Survival is the gold standard in oncology when determining the real impact of therapies in patients outcome. Thus, identifying molecular predictors of survival (like genetic alterations or transcripto...
Hypotaurine promotes glioma cell invasion by hypermethylating the Wnt5a promoter
Glioma is a particularly lethal central nervous system tumor. Identifying the boundary between gliomas and normal tissues is difficult due to their infiltrative and invasive growth characteristics. Th...
Leishmania regulates host YY1: Comparative proteomic analysis identifies infection modulated YY1 dependent proteins
The protein Yin-Yang 1 (YY1) is a ubiquitous multifunctional transcription factor. Interestingly, there are several cellular functions controlled by YY1 that could play a role in Leishmania pathogenes...
A study on the classification and prediction of firefighter’s operational fatigue level
Firefighting operations in high-rise building fires require firefighters to navigate complex environments while undertaking physically demanding, heavy-load tasks, which often lead to severe fatigue,...
How does high temperature weather affect tourists’ nature landscape perception and emotions? A machine learning analysis of Wuyishan City, China
Natural landscapes are crucial resources for enhancing visitor experiences in ecotourism destinations. Previous research indicates that high temperatures may impact tourists’ perception of landscapes...
Numbers of Eurasian beaver (Castor fiber) in the Czech Republic, causes of their admission to rehabilitation centres and release rates in the period from 2010 to 2020
The Eurasian beaver (Castor fiber) is the largest European rodent. This endangered species is an ecosystem engineer capable of providing several positive impacts in the ecosystems. However, it is also...
Serum interferon-gamma-induced protein 10 levels can help predict sarcopenia development in patients with primary hepatocellular carcinoma: A retrospective cohort study
Background Sarcopenia is a prognostic factor in patients with hepatocellular carcinoma (HCC). However, the mechanism underlying sarcopenia development in these patients remains unc...
Scenic area attractiveness in Dali City and its influencing factors evaluated using multi-source spatiotemporal data
Scenic area attractiveness is a core factor in urban tourism development. Developments in social media and multi-source spatiotemporal data provide a basis for studying complex tourist behaviors, over...
Disentangling behavioral determinants of seasonal influenza vaccination in post-corona era: An integrated model approach
Seasonal influenza vaccination (SIV) is influenced by various factors, including sociodemographic characteristics and socioeconomic status of the recipient. Nevertheless, in the post-COVID-19 era, the...
The development of the Polish version of the Compassionate Engagement and Action Scales
Compassion has been a subject of extensive scientific research for over two decades. There is clear evidence that our capacity for compassion evolved out of care motivation. Like all motivations it is...
Flat out Fabulous: How Barbie’s foot posture and occupations have changed over the decades, and the lessons we can learn
Objectives To explore the correlations/relationships between foot posture, equity and diversity, employment, and time in Barbie Land. Design A retrospective audit of the Barbie population (or their...
The differential burden of acute rhinovirus infections in children with underlying conditions
Introduction Rhinoviruses (RVs) are a well-known trigger of wheezing episodes in children with asthma. Their role in other pediatric chronic medical conditions is not fully known....
Targeting long non-coding RNA RP11-502I4.3 inhibits the trend of angiogenesis in diabetic retinopathy
Diabetic retinopathy (DR) is a leading cause of blindness. We hypothesised that the long non-coding RNA RP11-502I4.3 may be involved in angiogenesis associated with DR. We investigated the role of RP1...
Video map: A realtime orthographic geo-image considering DEM and semantic information
Aiming at the problem that it is difficult to accurately calibrate massive Pan-Tilt-Zoom Camera (PTZ) cameras on telecommunication tower and the visualization effect of orthographic geo-image is poor,...
BPChAr—a Benzene Polycarboxylic Acid database to describe the molecular characteristics of laboratory-produced charcoal: Implications for soil science and archaeology
The benzene polycarboxylic acid (BPCA) method is a technique to characterise the aromaticity and aromatic condensation of pyrogenic carbon (PyC) in charred residues. As a molecular marker for polycond...
The multi-level influence mechanism of family background on children’s education level: The moderating effect of socioeconomic status
Background A superior family background often provides children with more educational resources and a better learning environment, while poor or educationally deficient families may put children at a...
The effect of conservative non-pharmacological interventions on the management of urinary incontinence in older adults living with frailty: Systematic review and meta-analysis
Background Urinary incontinence (UI) is highly prevalent among older adults with frailty, impacting function, quality of life and risk of long-term care admission. Objective To systematically review...
Study on kinetics and thermsodynamics of municipal solid waste incineration fly ash in air and N2 atmospheres
This study attempted to investigate the thermal behavior and reaction mechanisms of municipal solid waste incineration fly ash under air and N2. Mass loss patterns at temperatures from 30ºC to 1100ºC...
A remarkable new blue Ranitomeya species (Anura: Dendrobatidae) with copper metallic legs from open forests of Juruá River Basin, Amazonia
Poison dart frogs (Dendrobatidae) are known for their aposematic coloration and toxic skin, making them a frequent subject of interest and research. However, descriptions of new species of Ranitomeya...
Suppression of mechanical hypersensitivity and change in the expression of the dopamine D2 receptor by administration of anti-CGRP antibody into the trigeminal ganglion in trigeminal neuropathic pain model rats
Calcitonin gene-related peptide (CGRP) and dopamine D2 receptor (D2 receptor) are associated with neuropathic pain. However, their relationship is not well understood. To better establish their relati...
Experimental investigation of flexible eight-port asymmetric fed MIMO antenna with narrow-super-widebandn-s characteristics for future applications including internet of things
In this work, an eight-port MIMOn-s antenna with dual-band operation is presented. The proposed work involves several wireless applications with FR1 and FR2 millimeter-wave bands. Also, a need for con...
Wild gelada monkeys detect emotional and prosocial cues in vocal exchanges during aggression
Recognizing vocal behaviours intended to benefit others is a crucial yet understudied social skill. Primates with rich vocal repertoires and complex societies are excellent models to track the evoluti...
Expectations regarding the effectiveness of mask-wearing and pandemic fatigue: The experience in Japan
Even though mask-wearing was merely “recommended” in Japan during the COVID-19 pandemic, the mask usage rate was higher than that in other countries. This study conducted an econometric analysis to ex...
Maximum likelihood estimation of age-specific incidence rate from prevalence
Usually, age-specific incidence rates of chronic diseases are estimated from longitudinal studies that follow participants over time and record incident cases. However, these studies can be cost- and...