PLoS ONE
Articles in this Issue
The quantitative enamel firing technique based on regression analysis
Enamel firing, as a key technique of enamel craftsmanship, has had no quantitative standards to follow since ancient times. To solve this problem, linear regression analysis was used to conduct quanti...
Benchmarking Differential Abundance Tests for 16S microbiome sequencing data using simulated data based on experimental templates
Differential abundance (DA) analysis of metagenomic microbiome data is essential for understanding microbial community dynamics across various environments and hosts. Identifying microorganisms that d...
Continuous emergence of phototaxis in Dictyostelium discoideum
The evolutionary transition from uni- to multicellularity is associated with new properties resulting from collective cell behavior. The social amoeba Dictyostelium discoideum alternating between indi...
Anomaly recognition in surveillance based on feature optimizer using deep learning
Surveillance systems are integral to ensuring public safety by detecting unusual incidents, yet existing methods often struggle with accuracy and robustness. This study introduces an advanced framewor...
A comprehensive analysis of two types of xenogeneic bone particles for use in maxillofacial bone regeneration therapies
Regeneration of maxillofacial bone structures is challenging. One strategy for bone damage repair involves using bone filler particles. This study analyzed the regenerative potential of deproteinized...
Inverse modeling, analysis and control of twin rotor aerodynamic systems with optimized artificial intelligent controllers
This paper suggests a novel optimal inverse Radial Basis Function (RBF) neural network model for the control of Twin Rotor Aerodynamic Systems (TRAS), such as Multi-Input–Multi-Output (MIMO) systems w...
Effect of Helicobacter pylori eradication on remnant stomach neoplasms after curative gastrectomy (HELP-GC): Protocol of a HELP-GC randomized controlled trial
Background Limited research has examined the direct effectiveness of Helicobacter pylori eradication (HPE) on the remnant stomach neoplasms after curative gastrectomy. This study aims to assess whethe...
“Our kids are our future”: Barriers and facilitators to vaccine uptake and timeliness among Aboriginal children younger than five years in Boorloo (Perth), Western Australia
Introduction Rates of several vaccine preventable diseases, and associated hospitalisation, are higher among Aboriginal and/or Torres Strait Islander children than non-Indigenous children. Western Aus...
Vibrio harveyi plasmids as drivers of virulence in barramundi (Lates calcarifer)
Vibrio species are an emerging public and animal health risk in marine environments and the opportunistic bacterial pathogen Vibrio harveyi...
Outcomes and experiences of DIALOG+ provided remotely for patients with anxiety disorders—A non-controlled pilot trial
Background Low-cost interventions in routine care are needed to reduce the burden of anxiety disorders. DIALOG+ is an evidence-based intervention specifically designed to make routine patient-clinicia...
Model reference adaptive system and pseudo-sliding mode control with exponential reaching law for sensorless-speed control of PMSM
Sensorless speed motor drives are essential for developing control techniques, reducing cost, streamlining the system, and enhancing reliability. This study explores the area of sensorless speed contr...
Developing a machine learning algorithm to predict psychotropic drugs-induced weight gain and the effectiveness of anti-obesity drugs in patients with severe mental illness: Protocol for a prospective cohort study
Obesity is a global public health concern, often co-occurring in patients with severe mental illnesses. The impact of psychotropic drugs-induced weight gain is augmenting the disease burden and health...
Correction: Advanced design and Engi-economical evaluation of an automatic sugarcane seed cutting machine based RGB color sensor
Validation of retroactively derived T1 relaxation values from 3D T1-weighted images with clinical and MRI measures of disability in multiple sclerosis
Background Quantitative T1 mapping is a valuable technique for assessing tissue injury in multiple sclerosis (MS) lesions. We previously introduced a novel methodology for converting high-resolution a...
Association of the newly proposed dietary index for gut microbiota and hyperlipidemia: From the 2007–2020 NHANES study
Objective The purpose of this study was to investigate the relationship between the Dietary Index for Gut Microbiota (DI-GM) and hyperlipidemia (HL). The DI-GM, a novel index for assessing gut microbi...
Conditioning invasive bigheaded carps (Hypophthalmichthys molitrix and H. nobilis)to enhance the efficacy of acoustic and CO2 deterrents
Invasive bigheaded carps (Hypophthalmichthys molitrix and H. nobilis) have caused substantial ecological and economic damage throughout the Mississippi River Basin and expanded their range threatening...
Strategies for improved endothelial cell adhesion in microphysiological vascular model systems
Human tissue-engineered blood vessels (TEBVs) have been applied as model systems to study a wide range of vascular diseases including Hutchinson-Gilford Progeria Syndrome and early atherosclerosis. Ce...
Protocol: Filgotinib in addition to methotrexate versus filgotinib monotherapy in patients with rheumatoid arthritis with an inadequate response to methotrexate: A multicenter, prospective, open-label, randomized controlled trial (FAITHFUL Study)
Background Filgotinib (FIL), a Janus kinase-1 preferential inhibitor, has been studied for its efficacy and safety in rheumatoid arthritis. The FINCH3 trial compared FIL monotherapy, FIL plus methotre...
Understanding the epidemiology and pathogenesis of Mycobacterium tuberculosis with non-redundant pangenome of epidemic strains in China
Tuberculosis is a major public health threat resulting in more than one million lives lost every year. Many challenges exist to defeat this deadly infectious disease which address the importance of a...
Hybrid deep learning model for accurate and efficient android malware detection using DBN-GRU
The rapid growth of Android applications has led to an increase in security threats, while traditional detection methods struggle to combat advanced malware, such as polymorphic and metamorphic varian...
Process evaluation for enhanced production of aflatoxin-free citric acid by food-grade Aspergillus niger
Aspergillus niger is considered as the main horsepower for the production of 90% of citric acid worldwide. Citric acid is produced under submerged fermentation and the process yield depends on A. nige...
Effect of simulated handball match-induced fatigue on isokinetic hamstring-to-quadriceps ratio and evertor-to-invertor ratio in professional players
Knee and ankle injuries are the most common injuries in handball players. Many of these injuries occur toward the end of the game when fatigue sets in. The underlying mechanisms of this phenomenon are...
An anatomically informed computational fluid dynamics modeling approach for quantifying hemodynamics in the developing heart
Congenital heart defects occur in approximately 1% of newborns in the US annually. Currently, less than a third of congenital heart defects can be traced to a known genetic or environmental cause, sug...
Synovial Gene expression after Hemarthrosis differs between FVIII-deficient mice treated with recombinant FVIII or FVIII-Fc Fusion Protein
To investigate if FVIII-Fc Fusion protein (FcFVIII) may modulate inflammation and immune stimulation in hemophilic synovium via the Fc-portion of immunoglobulin used for half-life extension we perform...
The effectiveness of pulsed electromagnetic field therapy in patients with shoulder impingement syndrome: A systematic review and meta-analysis of randomized controlled trials
We performed a systematic review and meta-analysis to assess the efficacy of pulsed electromagnetic field (PEMF) therapy in treating patients with shoulder impingement syndrome. We sourced data from P...