Antiviral potential of proton-type zeolite

Y Yuka Kimura M Masanori Takemoto N Noriko Nakamura (Institute of Engineering Innovation, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-8656, Japan) T Takeshi Ichinohe M Makoto Nakakido K Kenta Iyoki S Seiichi Ohta (Institute of Engineering Innovation, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-8656, Japan) N Nobuhiro Miyamae Y Yuki Egami K Koichi Sato T Tatsuya Okubo (Department of Chemical System Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan) K Kouhei Tsumoto T Toru Wakihara (Institute of Engineering Innovation, School of Engineering, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-8656, Japan)

Abstract

This study reports the potent antiviral ability of proton-type zeolites without the aid of any metal cations. Antiviral activities of zeolites with different topologies and chemical compositions are investigated using M13 phage and influenza virus. Proton-type zeolites exhibit excellent antiviral activity, equivalent to 99% inactivated. Antiviral tests using a centricon device suggest that direct contact of viruses on the external surface of zeolites is required to inactivate the viruses. This discovery is of importance in an interdisciplinary research field covering both zeolite science and virological science and shed light on the possibility of the development of low-cost and environmentally friendly antiviral zeolites.

Article Details

Journal PLoS ONE
Volume / Issue Vol. 20, Issue 5
Published May 27, 2025
Pages e0324484
ISSN 1932-6203
Publisher Public Library of Science

Journal Info

PLoS ONE

Public Library of Science

ISSN: 1932-6203 Open Access Health Sciences

Authors (13)

Y

Yuka Kimura

M

Masanori Takemoto

N

Noriko Nakamura

Institute of Engineering Innovation, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-8656, Japan

T

Takeshi Ichinohe

M

Makoto Nakakido

K

Kenta Iyoki

S

Seiichi Ohta

Institute of Engineering Innovation, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-8656, Japan

N

Nobuhiro Miyamae

Y

Yuki Egami

K

Koichi Sato

T

Tatsuya Okubo

Department of Chemical System Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan

K

Kouhei Tsumoto

T

Toru Wakihara

Institute of Engineering Innovation, School of Engineering, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-8656, Japan