PLoS ONE
Articles in this Issue
Integrated in silico identification of cholinesterase inhibitors from Nyctanthes arbor-tristis
Alzheimer’s disease (AD) remains a major neurodegenerative disorder, characterized by cognitive decline alongside functional impairments that affect daily living. Natural therapeutic alternatives have...
Molecular epidemiology and genetic diversity of Anaplasma and Theileria spp. in Pakistani sheep
Pakistan has a huge sheep population (37.2 million in 2024) that is largely unexplored for the presence of vector transmitted parasites. Present study was aimed to document the prevalence of Anaplasma...
Novel potential of low calorie plant burger: Functional turkey meat formulation optimized by replacing quinoa, chia, soy, amaranth and peas as vegetable protein and their influence on texture and sensory traits
This study explores the creation of a nutritionally and low-calorie turkey burger by integrating plant-based protein concentrates. Turkey burgers formulated with quinoa, chia, soybean, amaranth and pe...
The infectious diseases clinical research program acute respiratory infection repository protocol: Opportunities to understand current and future epidemics
Background Acute respiratory infections (ARI) are a major cause of morbidity and lost workdays in both military and non-military populations. To better understand these infections...
Factors influencing the performance of cardiopulmonary resuscitation by lay rescuers: A qualitative study based on the Theory of Planned Behavior
Aims This study investigated the underlying causes for the current low rate of cardiopulmonary resuscitation (CPR) implementation among lay rescuers. Specifically, the study aimed to identify the fact...
Utilization of telerehabilitation in TKR patients: A systematic review
Introduction Advanced telerehabilitation technology helps physiotherapists monitor the patient’s treatment process after Total Knee Replacement. This study aimed to review the research on telerehabili...
Class-aware multi-source domain adaptation algorithm for medical image analysis using reweighted matrix matching strategy
Multi-source domain adaptation leverages complementary knowledge from multiple source domains to enhance transfer effectiveness, making it more suitable for complex medical scenarios compared to singl...
Temporal regularities of vocal exchange in Java sparrows
In human turn-taking, speakers alternate at very short intervals while avoiding overlaps. If speakers do not receive a vocal response from another party, they often repeat their utterance after the ex...
Repeatability of corneal measurements from the Casia2 anterior segment tomographer in a cataractous population
Purpose The purpose of this study was to investigate the repeatability of corneal power and thickness measures in a large patient cohort. Methods In this retrospective non-randomised cross sectional...
Association of weight-adjusted waist index and Albuminuria in children and adolescents: A national population-based study
Background Albuminuria is a recognized marker of early kidney damage and cardiometabolic risk in pediatric populations. While central obesity is known to contribute to renal dysfunction, the relevance...
An appraisal of fund of funds efficiency based on risk-adjusted performance measures: Application of an augmented WASPAS methodology
In the complex landscape of investment management, Fund of Funds play a crucial role in constructing diversified portfolios with professional oversight. However, evaluating the performance of Fund of...
A standardized criteria-based progressive shoulder exercise program is effective in managing rotator cuff-related shoulder pain: A prospective cohort study
Background Non-operative management of patients with rotator cuff related shoulder pain (RCRSP) has been shown to be effective with outcomes similar to operative interventions. Exercise therapy and ed...
Human health risk assessment of arsenic and potentially toxic elements exposure in bread and wheat flour in Northeast Iran
Background Bread, a staple food, is at risk of contamination from heavy metals that pose significant health hazards. This study aimed to assess the levels of heavy metals, including Cu, Zn, Fe, Al, Co...
Physically-constrained evapotranspiration models with machine learning parameterization outperform pure machine learning: Critical role of domain knowledge
Physics-informed machine learning techniques have emerged to tackle challenges inherent in pure machine learning (ML) approaches. One such technique, the hybrid approach, has been introduced to estima...
Effects of long COVID on healthcare utilization
Background While most research on Long COVID (LC) has focused on symptoms and quality of life, there remains a critical need to better understand the effect of LC on resource utilization. This study s...
Climate and water-table levels regulate peat accumulation rates across Europe
Background Peatlands are globally-important carbon sinks at risk of degradation from climate change and direct human impacts, including drainage and burning. Peat accumulates when there is a positive...
Iranian postmenopausal women’s perspectives on sexual satisfaction: A qualitative study
Sexual satisfaction is a key component of human sexuality and is often considered the final stage of the sexual response cycle. Menopause is a physiological phenomenon characterized by various physica...
Comparative analysis of soil organic carbon across different land types in plateau wetlands using Kriging interpolation based on spatial heterogeneity
Wetlands, as an important global carbon reservoir, contribute significantly to the terrestrial carbon cycle. However, the high spatial heterogeneity of wetland ecosystems poses a considerable challeng...
Nested PCR amplification of the mitochondrial hypervariable region for non-invasive eDNA detection of Cryptobranchus alleganiensis
Environmental DNA (eDNA) has proven an invaluable tool in detecting elusive, endangered, or otherwise hard-to-identify species in aquatic ecosystems. The Eastern hellbender salamander (Cryptobranchus...
Board informal hierarchy, strategic aggressiveness, and corporate ESG performance
Based on the stakeholder theory, relationship contract theory, and other theories, this study examined how the board informal hierarchy influences corporate ESG (Environmental, Social, and Governance)...
Value chain analysis of medicinal plants in Geoparks: Livelihoods of ethnic minorities based on non-timber forest products (NTFPs) in Vietnam
Non-timber forest products (NTFPs) support the livelihoods and economic activities of households and communities in both rural and urban areas worldwide. This study applies the value chain analysis (V...
An ICEEMDAN and SAX-based method for determining English reading comprehension status using functional near-infrared spectroscopy signals
Accurate, rapid, and objective reading comprehension assessments, which are critical in both daily and educational lives, can be effectively conducted using brain signals. In this study, we proposed a...
Correction: Correction: Feeding habit and diet composition of three fish species inhabiting Sor River, Baro-Akobo Basin of Ethiopia, East Africa
The metabolic ability of swallowtails results in the production of bioactive substances from plant components
Host plant selection may depend on the metabolic system in herbivorous insects. Although oligophagous insects take up specific host plant components, how host plant components and their biological act...
Barriers to early and effective overactive bladder management in male patients with lower urinary tract symptoms
Overactive bladder is underdiagnosed and undertreated in men as symptoms overlap with benign prostatic obstruction. This study identified barriers urologists encountered in effectively managing overac...