PLoS ONE
Articles in this Issue
Additive effects of Trichoderma isolates for enhancing growth, suppressing southern blight and modulating plant defense enzymes in tomato
Southern blight, caused by Sclerotium rolfsii, poses a significant economic threat to tomato cultivation. This study involved the isolation, characterization, and evaluation of three selected Trichode...
Competencies of lower-level community health centre leaders in annual health work planning and their influence on district performance in Busoga sub-region: A retrospective study
Introduction Lower-level community health centres play a crucial role in the delivery of primary healthcare services, and the competencies of their leaders can significantly influence district perform...
Brimonidine tartrate 0.15% drops to reduce low post-LASIK residual myopia: A retrospective study
Purpose Residual myopia following Laser-assisted in situ keratomileusis (LASIK) surgery poses a significant concern, with existing literature extensively detailing the use of timolol for treatment. Th...
Comparative effectiveness and safety of insulin reference biologics versus biosimilars for types 1 and 2 diabetes mellitus: Protocol for a systematic review of real-world studies
Introduction Diabetes mellitus is characterized by insulin deficiency or resistance. The two main types of diabetes mellitus are type 1 (T1DM) and type 2 (T2DM). Insulin is the mainstay of therapy for...
Association of serum Klotho with tinnitus prevalence, duration and severity: A cross-sectional study in middle-aged and older adults
Background As an anti-aging protein, although studies increasingly suggest that the Klotho plays a role in the auditory system, the link between serum Klotho levels and tinnitus remains poorly charact...
Low-cost computation for isolated sign language video recognition with multiple reservoir computing
Sign language recognition (SLR) has the potential to bridge communication gaps and empower hearing-impaired communities. To ensure the portability and accessibility of the SLR system, its implementati...
Differentiation of HL-60 cells into primed neutrophils for the evaluation of antiapoptotic effects of poorly soluble nanoparticles
Background Neutrophil apoptosis is an important determinant of intensity and duration of neutrophilic inflammation. The interaction of poorly soluble nanoparticles with primed neutrophils can reduce t...
Serum fibrinogen level and fibrinogen administration in patients with traumatic brain injury: A systematic review and meta-analysis protocol
Introduction Traumatic Brain Injury (TBI) is a leading cause of disability and death globally. It has a significant economic burden. Coagulopathy has been identified as one of the key factors contribu...
Emergency dispatchers as instructors of laypersons in unplanned out-of-hospital deliveries - Interdisciplinary qualitative study
Introduction Unplanned out-of-hospital delivery tasks are continuously increasing and are challenging to the emergency dispatcher, but there is scant research on them, especially from the perspective...
Expression of Concern: Magnitude and associated factors of disrespect and abusive care among laboring mothers at public health facilities in Borena District, South Wollo, Ethiopia
Effect of drought stress during critical developmental stages on morphological and grain yield-related traits in winter barley (Hordeum vulgare L.)
As the frequency of droughts increases, the breeding of new drought-tolerant cereal varieties may become increasingly important. However, the complex effects of drought stress on grain yield-related t...
Impact of web accessibility on cognitive engagement in individuals without disabilities: Evidence from a psychophysiological study
Web accessibility features on websites are designed for individuals with disabilities that include low vision and cognitive impairments, but such features can benefit everyone. This study investigates...
Positional distribution of transcription factor binding sites in the human genome
As transcription factors (TFs) play a major role in gene regulation, we studied their binding motifs (positional weight matrices, PWMs) and binding sites (TFBSs) in the human genome, and how TFs bind...
Psychophysiology of facial emotion recognition in psychopathy dimensions and oxytocin’s role: A scoping review
Psychopathy is characterized by social impairments that hinder effective societal functioning. It comprises two main dimensions: “Interpersonal-affective” and “Lifestyle-antisocial,” each associated w...
Characteristics of medical costs and resource use in patients with rheumatoid arthritis treated with and without glucocorticoids
Objectives To evaluate medical costs and resource use in patients with rheumatoid arthritis (RA) treated with and without oral or injectable glucocorticoids (GCs) as part of their initial treatment wi...
Research on the optimization method of inventory management of important spare parts of intercity railway
As cities grow, intercity railways are becoming increasingly popular for short trips between neighboring areas. These railways cater well to commuters and travelers, making reliable and cost-effective...
Digital infrastructure policies, local fiscal and financing constraints of Non-SOEs: Evidence from China
Digital infrastructure serves as a cornerstone of urban digital transformation and smart city development, yet its implications for local fiscal systems and micro-level enterprises remain underexplore...
Dominant ionic currents in rabbit ventricular action potential dynamics
Mathematical models of cardiac cell electrical activity include numerous parameters, making calibration to experimental data and individual-specific modeling challenging. This study applies Sobol sens...
Features extraction based on Naive Bayes algorithm and TF-IDF for news classification
The rapid proliferation of online news demands robust automated classification systems to enhance information organization and personalized recommendation. Although traditional methods like TF-IDF wit...
Evaluation of health effect on workers exposed to methyl bromide with prefrontal event-related potential
Methyl bromide (MB) is a potent fumigant used to control pests in soil and agricultural products. As an ozone-depleting substance, MB has been largely replaced by safer alternatives. MB is highly toxi...
Association between lifestyle-related factors and low back pain: Evidence from a Japanese population–based study
Low back pain (LBP) is a major public health issue, and lifestyle-related factors (LRFs) are increasingly recognized as key contributors to LBP. However, comprehensive studies using recent data concer...
Field study on routine procedures for navel care in neonatal calves on dairy farms in Eastern Germany
Clean conditions and prophylactic measures around calving are essential for the health and welfare of calves. Therefore, the objective of this study was to evaluate the association of different navel...
Investigating the impact of social media images on users’ sentiments towards sociopolitical events based on deep artificial intelligence
This paper presents the findings of the research aimed at investigating the influence of visual content, posted on social media in shaping users’ sentiments towards specific sociopolitical events. The...
Positioning of Chinese time nouns and adverbs: Evidence from corpus, acceptability, and processing studies
This study examines the syntactic placement and cognitive processing of time nouns and time adverbs in Mandarin Chinese, a language without overt tense morphology, highlighting how these temporal expr...