PLoS ONE
Articles in this Issue
STGATN: A novel spatiotemporal graph attention network for predicting pollutant concentrations at multiple stations
Accurately predicting air pollutant concentrations can reduce health risks and provide crucial references for environmental governance. In pollution prediction tasks, three key factors are essential:...
Whole exome sequencing reveals pathogenic variants in CNGA3, CACNA1F, and RPGRIP1 in consanguineous Pakistani families with diverse retinal phenotypes
This study investigates the genetic basis of retinal diseases in four consanguineous families from Pakistan, focusing on mutations in the CNGA3, CACNA1F, and RPGRIP1 genes that are implicated in retin...
Electroacupuncture versus sham electroacupuncture in treating low anterior resection syndrome after rectal cancer surgery: Study protocol for a randomized controlled trial
Purpose Low anterior resection syndrome (LARS), a frequent postoperative complication of rectal resection, has been shown to significantly impact patients’ quality of life. Electroacupuncture (EA), a...
Association of serum lysophosphatidylcholine acyltransferase 3 levels with metabolic variables and risk of type 2 diabetes mellitus: A cross-sectional study
Aims This study aimed to explore the role of serum lysophosphatidylcholine acyltransferase 3 (LPCAT3) in glucose and lipid metabolism and its association with type 2 diabetes mellitus (T2DM). Method...
Role of rosuvastatin and pitavastatin in alleviating diabetic cardiomyopathy in rats: Targeting of RISK, NF-κB/ NLRP3 inflammasome and TLR4/ NF-κB signaling cascades
Diabetic cardiomyopathy (DCM) is a serious outcome of type II diabetes mellitus (T2DM) and a key contributor to high morbidity and death in diabetic individuals. The current research is intended to el...
Risk factors associated with avascular necrosis following unstable slipped capital femoral epiphysis in pediatric patients: A systematic review and meta-analysis
Background The risk factors for avascular necrosis (AVN) in patients with unstable slipped capital femoral epiphysis (SCFE) were controversial and multifactorial. This meta-analysis summarizes existin...
How much does culture matter for preferences for redistribution? Evidence from panel data on immigrants in Germany
This study addresses a long-debated question in the humanities: does culture matter? This issue gains prominence in times of intense migration, when disputes about migrants integration and their impac...
Cyber-intimate partner violence (C-IPV) and its risk factors among women in Malaysia
Cyber Intimate Partner Violence (C-IPV) is a serious challenge that negatively impacts the physical, mental and social health of victims. This study aims to estimate the prevalence of C-IPV among Mala...
From ultraviolet-B to red photons: Effects of end-of-production supplemental light on anthocyanins, phenolics, ascorbic acid, and biomass production in red leaf lettuce
Plants possess an array of photoreceptors, such as UVR8, cryptochromes, and phytochromes, that perceive the spectral quality of light and regulate plant morphology, growth, and physiology. The use of...
Evaluating the inhibitory efficacy of Oxalis phytocompounds on monoamine oxidase B: An integrated approach targeting age related neurodegenerative diseases through molecular docking and dynamics simulations
Monoamine oxidase B (MAO-B) serves as a critical target in the management of neurodegenerative diseases (NDDs) such as Alzheimer’s and Parkinson’s due to its role in regulating oxidative stress and do...
Comparison of different positioning techniques for reduction of induced vertical deviation following Nishida procedure for the treatment of sixth nerve palsy
Purpose Induced vertical deviation is a potential complication following the Nishida procedure for the treatment of sixth nerve palsy. This study aims to compare different positioning techniques for t...
Variability in article processing charges of open-access publishing across medical specialties
Background Open-access (OA) journals provide public access to research but often impose a financial burden on researchers through article processing charges (APCs). The connection between APCs and ind...
Associations between fitness, movement behaviors, and immediate post-exercise blood pressure in older adults: A network perspective
Understanding the associated factors of immediate post-exercise blood pressure, a proxy for exercise blood pressure, is relevant for improving cardiovascular risk assessment and guiding interventions....
Machine learning approaches for predicting the link of the global trade network of liquefied natural gas
With the rising geopolitical tensions, predicting future trade partners has become a critical topic for the global community. Liquefied natural gas (LNG), recognized as the cleanest burning hydrocarbo...
AC-YOLO: A lightweight ship detection model for SAR images based on YOLO11
Synthetic Aperture Radar (SAR), renowned for its all-weather monitoring capability and high-resolution imaging characteristics, plays a pivotal role in ocean resource exploration, environmental survei...
Study on the propagation law of hydraulic fractures in heterogeneous permeability reservoirs
The development of unconventional oil and gas resources is increasingly shifting toward heterogeneous reservoirs with complex permeability distributions, making the effective control of hydraulic frac...
Evaluation capacity building in a rural Victorian community service organisation: A formative evaluation
Community service organisations are increasingly required to report on outcomes and evaluate program delivery. While commonplace in clinical health settings, such work is novel to the community sector...
Motivation and physical activity across Chinese adolescents: Based on latent profile analysis
Despite known links between motivation and physical activity, latent profiles of motivation among Chinese adolescents remain unexamined. Using the person-centered approach, this paper explores the rel...
How different cardioplegic solutions influence genes expression and cytokine response in an immature rat heart model of ischemia/reperfusion?
Introduction The use of cardioplegia not only achieves cardiac arrest but also minimizes ischemic/reperfusion (I/R) injury, potentially improving short- or long-term outcomes. The aim of this study wa...
Sickness absence rates in NHS England staff during the COVID-19 pandemic: Insights from multivariate regression and time series modelling
The COVID-19 pandemic placed immense strain on healthcare systems worldwide, with NHS England facing substantial challenges in managing staff illness-related absences amid surging treatment demands. U...
The Healthy Homes Study: Protocol for a cluster randomized trial of a place-based smoke-free home intervention in affordable housing
Introduction Comprehensive clean air policies reduce exposure to secondhand tobacco and cannabis smoke, as well as nicotine aerosols, and improve health outcomes. However, these policies often do not...
Expression of Concern: Barriers to cleaning of shared latrines in slums of Addis Ababa, Ethiopia
Cost-effectiveness assessment of liquid biopsy for early detection of lung cancer in Brazil
Introduction Lung cancer has a low survival rate due to late diagnosis, with most cases detected at advanced stages. Liquid biopsy, a non-invasive alternative to tissue biopsy, has emerged as a potent...
The global, regional and national burden of pancreatitis due to alcohol use: Results from the Global Burden of Disease Study 2021 and projections to 2040
Background Alcohol use is a major risk factor for pancreatitis and global mortality. Despite its impact, comprehensive analyses of the burden across regions and sociodemographic strata remain scarce....
Global stroke burden attributable to household air pollution: Insights from GBD 2021 and projections to 2040
Objectives To analyze the global stroke burden attributable to household air pollution (HAP) using Global Burden of Disease (GBD) 2021 data, examine its spatiotemporal patterns from 1990–2021, and pro...