PLoS ONE
Articles in this Issue
Temporal phenotyping of neutrophils in post-cardiac arrest syndrome and extracorporeal membrane oxygenation-assisted resuscitation: A pilot study
The role of extracorporeal membrane oxygenation in the immune response during cardiac arrest, as well as the role of the innate immune system—particularly neutrophils—in the pathophysiology of post-ca...
Implementation of a clinical interview guide to Multidimensional needs assessment in Palliative care (MAP): A multicenter mixed-methods feasibility study
Background A recent systematic review highlighted the lack of consensus on the needs that should be assessed in palliative care to develop the initial therapeutic plan. An agreed clinical interview gu...
Stable preservation and recovery of methylation marks from FTA elute cards in species with nucleated red blood cells using a customized DNA extraction method
Specialized chemically-coated paper cards, such as Flinders Technology Associates (FTA) cards, provide simple and reliable storage of nucleic acids by protecting DNA from degradation. Owed to their si...
An analysis of knowledge, attitude and practice gaps in scientific buffalo husbandry
Buffalo husbandry remains vital to India’s dairy sector, yet adoption gaps hinder productivity. This study assesses knowledge, attitudes, and practices (KAP) among 380 buffalo farmers in India, reveal...
Assessment of economic development of central business districts – A combination multi-criteria evaluation methodology
Background The economic development of central business districts (CBDs) is a key driver of urban economic growth and enhances regional competitiveness. However, existing research predominantly focuse...
The status in Africa of fall armyworm expressing genetic markers related to infestations of pasture, millet, alfalfa, and rice in the Americas
The establishment of the fall armyworm (FAW), Spodoptera frugiperda, in Africa is reported to have caused substantial agricultural losses since its detection in 2016 and subsequent spread into Asia an...
Optimizing ISO standard microbiological techniques for isolating Campylobacter from poultry samples amidst challenges from extended spectrum beta lactamase producing Escherichia coli
Isolation of zoonotic Campylobacter species has been standardized through the ISO 10272:2017 protocol. However, application of the protocol in a LMIC country failed to isolate Campylobacter due to ext...
Uncovering locomotor learning dynamics in people with Parkinson’s disease
Locomotor learning is important for improving gait and balance impairments in people with Parkinson’s disease (PD). While PD disrupts neural networks involved in motor learning, there is a limited und...
Carboxylic ligands and their influence on the structural properties of PbTe quantum dots
We present a low-cost, straightforward, and tunable hot-injection method for synthesizing PbTe quantum dots (QDs). By incorporating short-chain carboxylic acids—hexanoic acid (HexA), heptanoic acid (H...
How can health systems sustain lessons drawn from emergency contexts? Evidence from Colombia
The Covid-19 pandemic demanded rapid adaptation to health systems internationally, but little is known about the sustained value of the approaches to learning adopted. How does ongoing environmental t...
Government subsidy research on the application of IoT technology in contract-farming supply chain
Existing research have not yet focused on the mechanism of Internet of Things(IoT) technology’s impact on the contract-farming supply chain.We introduce the IoT technology into the contract-farming su...
Channelization and flow depletion shift benthic macroinvertebrate and fish communities in urban rivers
Aquatic ecosystems worldwide are increasingly affected by human activities, with urbanization representing a major source of environmental stress. Channelization and flow depletion are key stressors i...
Expression of concern: Analysis of cataract-regulated genes using chemical DNA damage induction in a rat ex vivo model
Clinical analysis and comparative study of facial symmetry of three-dimensional skull models
Facial symmetry is a critical determinant in maxillofacial reconstruction. To establish an ideal midsagittal plane (MSP) for three-dimensional (3D) skull model in the diagnosis and treatment of maxill...
Decoding past microbial life and antibiotic resistance in İnonü Cave’s archaeological soil
This study, which bridges the disciplines of archaeology and microbiology, examines the ancient bacterial communities and antibiotic-resistance genes in soil samples collected from İnönü Cave in Zongu...
Expression of Concern: Histone acetyltransferase inhibition reverses opacity in rat galactose-induced cataract
Effects of stimulus amplitude-scaling approach on emotional responses to non-speech sounds
In the study of auditory emotion perception, it is important to calibrate test sounds so their presentation level during testing is known. It is also often desirable to standardize the amplitude of th...
Adjuvantation of Kyasanur Forest Disease vaccine with TLR9 agonist CpG adjuvant enhances immunological efficacy and potency of the vaccine
The present study was carried out with the objectives of formulation of Kyasanur Forest Disease (KFD) vaccine adjuvanted with TLR9 agonist, CpG; evaluation of cell mediated and humoral immune response...
Evolution of strain diversity and virulence factor repertoire in pediatric Staphylococcus aureus isolates
Background Invasive Staphylococcus aureus infections cause high morbidity and mortality in children and adults. With rising antimicrobial resistance, optimal prevention strategies and novel therapeuti...
Understanding the impact of urban exposure on obesity among middle and old-age migrants in India
Rural-to-urban migration is associated with elevated obesity in Western settings. However, whether migration to urban areas ages has any impact on obesity in India is inconclusive and scarce. We, ther...
Divide-and-conquer routing for learning heterogeneous individualized capsules
Capsule Networks (CapsNets) have demonstrated an enhanced ability to capture spatial relationships and preserve hierarchical feature representations compared to Convolutional Neural Networks (CNNs). H...
Computational prediction of the pathogenic variants of arachidonate 5-lipoxygenase activating protein using Molecular Dynamics simulation
The arachidonate 5-lipoxygenase activating protein (ALOX5AP) regulates leukotrienes (LTs) synthesis. LTs are involved in inflammation which is implicated in cardiovascular diseases (CVDs) and stroke....
Human exposure to PM10 microplastics in indoor air
The ubiquitous presence of airborne microplastics (MPs) in different indoor environments prompts serious concerns about the degree to which we inhale these particles and their potential impact on huma...
Effects of long-term metformin intake on postoperative clinicopathological characteristics in patients with invasive lung adenocarcinoma and type 2 diabetes mellitus: A retrospective analysis
Objective This retrospective study aimed to evaluate whether long-term metformin use is associated with less aggressive clinicopathological characteristics in patients with invasive lung adenocarcinom...
Development of a core outcome set for trials for management of oral submucous fibrosis (OSFCOS): A consensus study protocol
Background The effectiveness of oral submucous fibrosis (OSF) treatment is currently assessed with a broad range of clinical outcome measures. This heterogeneity complicates study comparison, synthesi...