PLoS ONE
Articles in this Issue
Surgeon interpretation of patient-reported outcome measures in upper extremity osteoarthritis
Purpose Measures that quantify levels of pain intensity, incapability, symptoms of distress, and unhelpful thinking were designed as research tools. We studied how surgeons interpret and act on these...
Mother-child autonomic nervous system interaction as an indication of parental stress: 24-hour cross recurrence plot analysis
Mothers and children interact through behaviors and mutual physiological signals. Recent research has suggested that physiological interactions are sensitive biomarkers for parenting challenges such a...
Comparison of laparoscopic tubal-preserving surgical management versus methotrexate therapy for tubal pregnancy: A conventional and network meta-analysis
Background Tubal pregnancy is one of the common emergencies in obstetrics and gynecology. There are various treatment options for tubal pregnancy. However, there is no consensus on how patients should...
Effects of survey administration mode on response profiles are predictable, and robust across countries: Evidence from 29 countries using machine-learning models
Survey data collection can be administered in different modes, including face-to-face interviews and self-completion modes such as paper-and-pencil or web-based surveys. Do data collected in these dif...
Meaning in life, positive cognition, and learning motivation: A mediational analysis among Chinese college students
Background While a sense of meaning in life is known to boost students' learning motivation, the psychological process explaining how this happens is not well understood. This study investigated wheth...
Mechanisms that link circadian preference to problematic smartphone and social media use in young adults
Evening-types are at higher risk of problematic smartphone use and addiction to social media, but little is known about the possible mediating factors. Given the rising prevalence and broad negative i...
Evaluation of the Xpert MTB/XDR test for detection of isoniazid, fluoroquinolones, and second-line injectable drugs resistance to Mycobacterium tuberculosis—Anhui Province, China
Introduction The emergence of drug-resistant tuberculosis (DR-TB) has posed significant challenges to TB control. This study assessed the diagnostic performance of the Xpert MTB/XDR test for detecting...
General and special education teachers’ readiness for artificial intelligence in classrooms: A structural equation modeling study of knowledge, attitudes, and practices in select UAE public and private schools
As artificial intelligence (AI) reshapes global education systems, understanding educators’ readiness to integrate AI into classroom practices is essential. This study examines the knowledge, attitude...
Correction: Identification of the AKCDPK gene family and AkCDPK15 functional analysis under drought and salt stress
Virulence gene profile and antimicrobial resistance patterns of Aeromonas hydrophila in farmed catfishes (Heteropneustes fossilis and Pangasianodon hypophthalmus) for the first time in Bangladesh
Among several Aeromonas spp., causing diseases in fishes, Aeromonas hydrophila is the most predominant and pathogenic one. This study represents the first molecular detection, virulence profiling, and...
Prognostic follow-up of high-grade squamous intraepithelial lesions of the cervix near the conization margin: A retrospective cohort study
Objective This study explored the prognosis of high-grade squamous intraepithelial lesion (HSIL) patients with negative margins, investigating the impact of different distances between lesions and inc...
Association between hair cortisol levels and keratoconus: A prospective study
Introduction Keratoconus is a progressive corneal disorder characterized by corneal thinning often leading to significant visual impairment. Recent research suggests a potential role of cortisol in th...
Gene expression alterations in testicular biopsies from males with spermatogenesis arrest identified by transcriptome analysis
Spermatogenesis is a complex biological process encompasses several stages of cellular divisions, ultimately resulting in producing mature spermatozoa capable of fertilization. Numerous factors involv...
Impact of domestic and foreign investors on ESG disclosure quality in Chinese listed firms: Divergence or convergence?
Using the data of Chinese listed firms, this study constructs a two-layer complex network of Qualified Foreign Institutional Investors (QFII) and Domestic Institutional Investors (DII) to examine thei...
Pulsed electric field (PEF)–processed 6-shogaol-rich ginger extract protects β-Thalassemic red blood cells from iron-induced oxidative stress and hemolysis
β- thalassemia is the genetic blood disorder characterized by ineffective beta-globin chain synthesis. The increased iron absorption and frequently blood transfusion result in iron overload and the pr...
Research on dual-waterway cooling system of high-power-density permanent magnet synchronous machine
The issue of temperature rise and heat dissipation becomes crucial to enhancing motor performance as permanent magnet synchronous motors (PMSMs) for electric vehicles (EVs) advance toward high power d...
Genetic diversity and relationship of Bugesera and Rwamagana indigenous chicken populations with SASSO chickens using DArTseq SNPs
The genetic improvement of Rwandan indigenous chickens (IC) is becoming a priority and requires genetic characterization as the foundation for genetic improvement. The aim was to study the genetic div...
Trend analysis and projection of the gastric cancer disease burden in Taiwan during 1990–2021: An analysis of the global burden of disease study 2021
Background Gastric cancer is a serious health threat to people in Taiwan. This study reports gastric cancer burden and trends in Taiwan, from 1990 to 2021, and projects the incidence and mortality tre...
Assessing the real-world safety of docetaxel for non-small cell lung cancer: Insights from a comprehensive analysis of FAERS data
Background Docetaxel is a key therapeutic agent in the treatment of non-small cell lung cancer (NSCLC), but comprehensive real-world data on its adverse effects remain scarce. This study aims to evalu...
Analytical validation (accuracy, reproducibility, limit of detection) and gene expression analysis of FoundationOneRNA assay for fusion detection in 189 clinical tumor specimens
Targeted DNA-based comprehensive genomic profiling (CGP) to detect clinically significant alterations is increasingly becoming standard for patients with advanced or recurrent cancer. RNA-based sequen...
Application of machine learning algorithms to predict early childhood development in children aged 24–59 months across three East African countries
Background Early childhood development (ECD) plays a crucial role in shaping the future development of children and it influences their lifelong outcomes. The Early childhood development index 2030 (E...
Association between lactate-to-albumin ratio and 28-day ICU mortality in pediatric severe pneumonia patients
Introduction The lactate-to-albumin ratio (LAR) has emerged as a promising prognostic biomarker in critical care, reflecting both metabolic dysfunction and inflammatory status. However, its prognostic...
Study on the pathogenesis of varicocele induced by the ferroptosis of cremaster satellite cells with the m6A modification of TFRC mRNA
Background Varicocele (VC) is a leading cause of male infertility. Insufficient growth and development of the cremaster muscle may contribute to VC, but the underlying mechanism remains unclear. Crema...
Shade provision and its influence on water intake and drinking behaviour of Nellore cattle in feedlot in a tropical environment
Heat stress is a significant challenge in tropical beef production systems, affecting feed intake, water intake, and overall animal welfare. This study aimed to evaluate the impact of shade provision...
Applying the advocacy coalition framework to wildlife management: Explaining policy change for damage mitigation in Japan
Case studies in wildlife management and its policy often lack a unified analytical framework, there are few studies that have systematically investigated policy processes and pathways of policy change...