PLoS ONE
Articles in this Issue
Correction: Sarcopenic obesity in predialysis chronic kidney disease: Muscle strength is a predictor of mortality and disease progression in a six-year prospective cohort
A meta-analysis of the prevalence, genotype distribution and risk factors for human papillomavirus infection in Nepal
This systematic review and meta-analysis estimated the prevalence, genotype distribution, and risk factors for human papillomavirus infection among Nepalese women. A total of 8 cross-sectional studies...
Identifying the influencing factors for cataract surgery uptake in Malaysia
Background/Aims In 2014, Malaysia conducted National Eye Survey II (NES II) using the World Health Organization (WHO)-recommended Rapid Assessment of Avoidable Blindness (RAAB) methodology across six...
Traumatic brain injury reprograms lipid droplet metabolism shaped by aging and diet in Drosophila brain
Traumatic brain injury (TBI) initiates secondary cellular damage such as mitochondrial dysfunction, oxidative stress, and neuroinflammation. In neurodegenerative disorders, these stressors are associa...
An interpretable LightGBM model for predicting coronary heart disease: Enhancing clinical decision-making with machine learning
Background Coronary Heart Disease (CHD) is one of the major burdens of cardiovascular diseases worldwide. Traditional diagnostic methods, such as coronary angiography and electrocardiogram, face chall...
Region-specific variation and determinants of caesarean delivery among ever-married women in Bangladesh
Background The extensive use of caesarean delivery has adverse consequences for both maternal and neonatal health. This study aims is to investigate regional variation and identify region-specific det...
Comparative outcomes of laparoscopic lateral suspension, sacrocolpopexy, and transvaginal mesh for advanced apical prolapse: A retrospective cohort study
Objective To compare perioperative outcomes and long-term anatomical/functional efficacy of laparoscopic lateral suspension (LLS), laparoscopic sacrocolpopexy (LSC), and transvaginal mesh (TVM) proced...
The increase in varus tilt of the joint line convergence angle under weight-bearing is correlated with medial meniscus extrusion in patients with knee osteoarthrosis
Background Increased medial meniscus extrusion (MME) in weight-bearing conditions is a critical factor associated with knee osteoarthritis (OA) progression and is not an alternativ...
Dissecting the dynamics of virus-derived DNA of dengue virus 2 (DENV-2) in Aedes mosquitoes
Dengue is one of the neglected tropical diseases (NTDs) transmitted by Aedes mosquitoes and continues to spread globally. When mosquitoes are infected with dengue virus (DENV), virus-derived DNA (vDNA...
How facemasks shape trust in social interactions
Face coverings can potentially impact how trustworthy someone appears through two channels: by hiding important facial cues associated with trust; or by signalling the wearer’s intentions or personal...
Correction: Variants in the CETP gene affect levels of HDL cholesterol by reducing the amount, and not the specific lipid transfer activity, of secreted CETP
Trends and inequalities in full immunization coverage among two-year-olds in Sierra Leone, 2008–2019
Background Immunization is a cornerstone of public health, preventing numerous vaccine-preventable diseases. However, disparities in immunization coverage persist globally, particularly in low-income...
Whole blood RNA profiling in cats dissects the host immunological response during recovery from feline infectious peritonitis
Feline infectious peritonitis (FIP) is caused by infection with the feline coronavirus (FCoV) and is fatal if left untreated. In most cats, FCoV primarily infects the gastrointestinal tract and remain...
A multi-group path analysis of medication documentation quality using cross-sectional survey data: Impact of leadership, job satisfaction, patient-related burnout, and patient safety culture
Medication-related adverse events are a major problem for patient safety and quality of care. This study explored the effects of leadership, job satisfaction, patient-related burnout and patient safet...
New frontiers in radiologic interpretation: evaluating the effectiveness of large language models in pneumothorax diagnosis
Background This study evaluates the diagnostic performance of three multimodal large language models (LLMs)—ChatGPT-4o, Gemini 2.0, and Claude 3.5—in identifying pneumothorax from chest radiographs....
Albumin-corrected anion gap as a predictive marker for mortality in critically Ill cirrhosis patients: an analysis based on the MIMIC-IV database
Background The prognostic value of Albumin-Corrected Anion Gap (ACAG) has been extensively examined across a range of diseases; however, its relationship with short- and long-term survival in critical...
Effect of sensory-motor intervention associated with skin-to-skin contact on neuromotor and clinical outcomes of preterm newborns: A randomized controlled trial
Objective To examine the effects of a physical therapy sensory-motor intervention combined with kangaroo skin-to-skin contact in clinically stable preterm newborns. Design, setting, and participants...
Correction: Fibrinogen and colorectal cancer: A study of the Chinese population
Analytical approach of synchronous and asynchronous update schemes applied to solving biological Boolean networks
Characterizing the minimum, necessary and sufficient components to generate the dynamics of a biological system has always been a priority to understand its functioning. In this sense, the canonical f...
Unmasking the effects of E-leadership on virtual team effectiveness by an integrated fsQCA and NCA method
Together with unstoppable trend of business going digitally global in recent years and the worldwide spread-out of COVID-19 since 2020, virtual teams have gradually garnered considerable attention in...
FloralArea: AI-powered algorithm for automated calculation of floral area from flower images to support plant and pollinator research
Floral area is a major predictor of the attractiveness of a flowering plant for pollinators, yet the measurement of floral area is time-consuming and inconsistent across studies. Here, we developed an...
Phytochemical profiling and bioactivity validation of Moringa oleifera leaves: Antimicrobial, antidiarrheal, analgesic, and in silico insights
The increasing threat of antimicrobial resistance and the need for new medicines have renewed interest in medicinal plants like Moringa oleifera Lam., a fast-growing tree from the Moringaceae family t...
Combining ability and heterosis analysis for mineral content in the leafy vegetable Gynandropsis gynandra (L.) Briq.
Spider plant (Gynandropsis gynandra) is a leafy vegetable rich in micronutrients, including minerals, vitamins, and secondary metabolites, making it a valuable opportunity crop for combating hidden hu...
Eculizumab and ravulizumab clinical trial and real-world pharmacovigilance of meningococcal infections across indications
Introduction Complement component 5 inhibitor therapies (C5ITs) for rare hematological, renal, and neurological diseases are associated with increased meningococcal infection risk. Robust risk mitigat...
A novel sialylation pathway mediated by extracellular vesicles in aggressive prostate cancer
Altered cell surface glycosylation is a hallmark of cancer; among aberrant glycan structures, hypersialylated proteins contribute to disease progression. The enzyme ST6 β-galactoside α2,6-sialyltransf...