PLoS ONE
Articles in this Issue
Integration of mathematical modeling and economics approaches to evaluate strategies for control of Salmonella Dublin in a heifer-raising operation
Salmonella Dublin infections in heifer-raising operations (HROs) cause animal health and economic losses for these operations and represent a pathogen source for dairy farms obtaining replacement heif...
Land consolidation drives changes in soil bacterial community structure and promotes positive bacterial interactions
Understanding how land consolidation influences bacterial community structure and interactions is essential for advancing ecological restoration and sustainable land management. However, current knowl...
A diffusion of innovations measurement scale for reinvention, relative advantage, compatibility, complexity, trialability and observability
Diffusion of innovations (DOI) theory identifies critical factors that influence technology adoption rates and offers a predictive model for understanding how innovations spread through populations. W...
Active expiration reduces hypercapnia in lung failure – results of the prospective interventional ActiveEx study and development of a prototype device for automated application
Background This study investigates the efficacy of Intermittent Abdominal Pressure Ventilation (IAPV) and Expiratory Rib Cage Compression (ERCC) in reducing hypercapnia among critically ill, mechanica...
Editorial note: The spatial and temporal situation of China’s digital technology innovation and its influencing factors
Care professionals’ accounts of providing support and treatment for people with co-occurring alcohol use disorder and depression in the North East of England, UK: A qualitative study informed by complexity theory
Introduction There is an acknowledged care gap for patients with co-occurring substance use and mental ill-health. This study sought to use complexity theory to help make sense of the experiences of p...
A multi-disciplinary approach to identify spillover interfaces of bat coronaviruses to pig farms in Italy
Bats are recognized reservoirs of diverse coronaviruses (CoVs), but little is known about the pathways enabling their spillover into livestock. This study applied a multidisciplinary approach, combini...
The degraded contingency test fails to detect habit induction in humans
In experimental psychology and behavioral neuroscience, habits are considered stimulus-response (S-R) associations formed through extended reward training. Accordingly, habits are assessed using one o...
Association between community-based resource collection site use and functional disability risk among older adults: A Quasi-experimental study
This study aimed to investigate the longitudinal association between users versus non-users of MEGURU STATION, a community-based resource collection site, and the risk of functional disability among o...
Exploring the relationship between housing conditions and risk perception in a disaster context
The relationship between housing conditions and risk perception is overlooked commonly in disaster studies. Correspondingly, this research study helps in filling this research gap by answering the two...
Automated software bug severity classification using ensemble machine learning scheme: A real case study
Software bug report classification is one of the most significant processes in software development for determining the nature and severity of faults based on their causes and effects. In many project...
Informal care in different European care systems: Effects of caregiving on mental health over time
Background The study explores the impact of informal caregiving on mental health within different European care systems, recognizing the significant role of informal care due to de...
Risk of atopic dermatitis in periodontitis patients with and without dental scaling: A retrospective cohort study
Background Both atopic dermatitis (AD) and periodontitis are common chronic inflammatory diseases. However, the association between AD and periodontitis remains poorly understood. This study aimed to...
Who gets sicker and why? Parents’ perceptions of COVID-19 disparities and how they would explain them to their children
The COVID-19 pandemic revealed substantial health disparities, disproportionately impacting Black individuals, individuals of lower socioeconomic status, and older adults in the US. Little is known as...
Prevalence and risk factors of Influenza Avian Virus in backyard pigeons, ducks, and chickens in Toba Tek Singh District, Pakistan
Influenza Avian virus (IAV) is a zoonotic pathogen that can be transmitted from birds to humans. Multiple IAV pandemics have had a devastating impact on the poultry industry and backyard birds (includ...
Synergistic antibacterial effect of hydroxyl radicals generated by the combination of hypochlorous acid and UV irradiation
Livestock farms are at risk of exposure to various environmental pollutants, particularly airborne viruses that can cause infectious diseases. Hydroxyl radicals (•OH) are well-known for their strong b...
Impact of group antenatal care on lactational amenorrhea method awareness and knowledge: A cluster randomized control trial
High fertility rates in low and middle-income countries (LMICs), especially in sub-Saharan Africa and Ghana, lead to closely spaced pregnancies and contribute to high maternal and infant morbidity and...
Humanized monoacylglycerol acyltransferase 2 mice on a high-fat diet exhibit impaired liver detoxification during metabolic dysfunction-associated steatotic liver disease
Obesity significantly increases the risk of hyperlipidemia, type 2 diabetes, and liver disease. This study examined humanized monoacylglycerol acyltransferase 2 mice (HuMgat2) and their response to a...
Association between food insecurity, ethnicity, and mental health in the UK: An analysis of the Family Resource Survey
The study aimed to assess the relationship between food insecurity and ethnicity in the United Kingdom (UK), and to explore how the relationship between food insecurity and mental health varies by eth...
Suppression of kinesin family member-18A diminishes progression and induces apoptotic cell death of gemcitabine-resistant cholangiocarcinoma cells by modulating PI3K/Akt/mTOR and NF-κB pathways
Cholangiocarcinoma (CCA), particularly when associated with Opisthorchis viverrini infection, is often diagnosed at a late stage and exhibits high resistance to chemotherapy, notably gemcitabine. Whil...
VISION: View-specific integrated segmentation-classification framework for accurate brain tumor detection in MRI scans
Brain tumors are an increasing global health concern, and accurate diagnosis is essential for improving patient outcomes. Although existing Magnetic Resonance Imaging (MRI)-based machine learning util...
Comparing the effects of interactive and conventional video education on activation, treatment adherence, and weight changes in dialysis patients: A randomized clinical trial protocol
Background Patients with end-stage renal disease undergoing hemodialysis face substantial challenges in adhering to complex therapeutic regimens, significantly impacting morbidity, mortality, and qual...
Learning to detect AI texts and learning the limits
This study investigates whether individuals can learn to accurately discriminate between human-written and AI-produced texts when provided with immediate feedback, and if they can use this feedback to...
Land surface temperature evolution in rapidly urbanizing areas of Southeast Asia: Studies from Vietnam and Cambodia
Land surface temperature (LST) is one of the crucial variables in urban microclimate studies. Satellite-based thermal data and vegetation indices, like the normalized difference vegetation index (NDVI...
STAG2 regulates polycomb and differentiation in urothelial precursors and bladder cancer
The STAG2 tumor suppressor gene is commonly inactivated by mutations in a wide range of common cancer types. STAG2 encodes a component of the cohesin complex, which controls sister chromatid cohesion...