PLoS ONE
Articles in this Issue
Cytotoxic, anti-inflammatory, antioxidant, and anti-glyoxalase-I evaluation of chelating substances: In silico and in vitro study
Introduction Glyoxalase I is a crucial target in cancer treatment due to its involvement in detoxifying methylglyoxal. Suppressing the activity of Glyoxalase I has great potential for disrupting the p...
Taxonomic study of the genus Diolcogaster Ashmead (Hymenoptera, Braconidae, Microgastrinae) from Borneo with the description of four new species
Taxonomic studies of Microgastrinae (Hymenoptera: Braconidae) are seldom conducted on material from Borneo, despite its being widely recognized as one of the world’s biodiversity hotspots. As part of...
Deep memory for deep threats: A novel architecture combining GRUs and deep learning models for IDS
The increasing volumes and sophistication of cyber threats, particularly Denial-of-Service (DoS) and Distributed Denial-of-Service (DDoS) attacks, pose significant dangers to contemporary network stru...
Associations of sunlight affinity with depression and sleep disorders in American males: Evidence from NHANES 2009–2020
Objective Depression and sleep disorders are globally prevalent, yet male-specific studies remain scarce. This study investigates associations between sunlight affinity (a novel dual-dimensional metri...
Evaluating topological variability in Neodermata phylogenies using mitochondrial and ribosomal gene markers
The Neodermata is a group of parasitic flatworms that includes the classes Trematoda, Cestoda, and Monogenea. Understanding the phylogenetic relationships within the Neodermata has been a longstanding...
Dissecting fuel demand elasticities in Ghana: A quantile regression analysis using the Marshallian demand framework
Our study investigates fuel demand elasticities in Ghana by assessing consumer responses to income and price changes using the Marshallian demand framework. Applying Ensemble Empirical Mode Decomposit...
Multiplex serology for Streptobacillus moniliformis and other ‘rat bite fever-like’ microorganisms for seroprevalence studies in rodents
Rat bite fever (RBF) is a zoonotic disease caused primarily by Streptobacillus (S.) moniliformis. Norway or brown rats (Rattus [R.] norvegicus) are the natural host for S. moniliformis and carry the b...
A prospective single-masked, non-inferiority, parallel-group randomized controlled trial of the efficacy of a ChatGPT-based AI chatbot to improve Boston bowel preparation scores for colonoscopy preparation: A trial protocol
Artificial intelligence (AI) is transforming healthcare through tools like large language model chatbots. AI chatbots can simulate human conversation, provide personalized information, and interact wi...
When access ≠ acceptance: How clinical specialty demands shape mutual recognition on medical examination/test result reuse in Chinese hospitals: A study on a pilot province of China’s medical digital reform
Background Despite widespread electronic health records adoption, interoperability for sharing examination/test results across healthcare institutions remains limited, leading to redundant testing, in...
Orthogonal position representations for transformer in neural machine translation
In recent years, the Transformer architecture has solidified its position as the dominant model in neural machine translation (NMT), thanks to its exceptional effectiveness in capturing long-range dep...
Rural-urban disparity in induced abortion in Ghana: A multivariate non-linear decomposition analysis of the Ghana Maternal Health Survey
Globally, 73.3 million induced abortions were recorded between 2015 and 2019. There are significant disparities in induced abortions across the rural-urban divide that necessitate targeted policies. I...
Barriers and strategies in detection and management of elevated Lipoprotein(a) in hospital: A pre-implementation qualitative study of cardiology healthcare professionals
Background Elevated Lipoprotein(a) [Lp(a)] is a genetic risk factor for cardiovascular diseases affecting 20% of the world’s population, with multiple published consensus statements that recommend tes...
Knowledge and practices about vocal hygiene among speech-language pathologists in India
Background The objective of the present study was to explore the knowledge and practices about vocal hygiene among speech language pathologists in India. Methods An online survey was conducted to ex...
Multidisciplinary study of human remains from the 3rd century mass grave in the Roman city of Mursa, Croatia
During excavations in 2011, a peculiar archaeological feature representing a mass grave with seven completely preserved skeletons was discovered at the site of the Roman period city of Mursa (modern-d...
Leveraging enhanced perceptual markings for accident prevention in long-range applications near freeway exits: Evidence from driving simulation experiments
Perceptual markings are extensively applied in practice for accident prevention, especially at the high-risk segments and/or sites, such as the freeway exits. However, most of the present perceptual m...
In vivo assessment of buparvaquone resistant Theileria annulata populations: genetic structure, transmission dynamics, drug susceptibility and pharmacokinetics
Tropical theileriosis, caused by the protozoan parasite Theileria annulata and transmitted by several species of ixodid ticks of the genus Hyalomma, is an economically important disease of bovines. Co...
Bridging the attitude-behaviour gap: An explanation of travel mode choice using analytical sociology
The aim of this work is to improve the explanatory power of models of transport mode choice and thus contribute to the mobility transition. The authors develop a new model of mobility behaviour called...
Multi-objective dung beetle optimization algorithm: A novel algorithm for solving complex multi-objective optimization problems
Many increasingly complex multi-objective optimization problems are emerging, and there is an urgent need to develop new multi-objective optimization algorithms to meet the challenges. This study intr...
A FtsZ inhibitor-acinetobactin conjugate with enhanced cellular uptake in Acinetobacter baumannii acts synergistically in combination with PBP3-targeting antibiotics
Multidrug resistance in the Gram-negative bacterial pathogen Acinetobacter baumannii is a global public health threat, highlighting a critical need for drug development. FtsZ is an essential cell divi...
Data-driven Bayesian networks for risk scenario mapping of Falls from height accidents
Falls from height (FFH) represent the most frequent type of accident in the building industry, leading to substantial economic losses and posing serious threats to worker safety. While risk analysis p...
Exploring the connection between pet attachment and owner mental health: The roles of owner-pet compatibility, perceived pet welfare, and behavioral issues
Research exploring the connection between pet ownership and mental health has expanded substantially in recent years, yet scientific evidence remains inconclusive. Existing studies have oversimplified...
Customer tolerance in homestays: The influence of interpersonal interaction and motivation Attribution
Customer tolerance behavior actively sustains harmonious host–guest relationships and strengthens homestay reputations. Drawing on social cognition theory and attribution theory, this study investigat...
Correction: Ozone efficacy for the control of airborne viruses: Bacteriophage and norovirus models
Delay, deny, and defend: Public outrage at health insurance companies and stock market debacle
This study investigates the stock market’s response to the assassination of UnitedHealthcare’s CEO, focusing on the cumulative abnormal returns (CARs) of publicly listed U.S. insurance firms. Using to...
Conditional generative adversarial network technology for OFDM system receiver signal detection
In response to the limited detection accuracy of traditional orthogonal frequency division multiplexing systems in complex wireless channel environments, this study first uses conditional generative a...