PLoS ONE
Articles in this Issue
Global burden of Alzheimer’s disease and other dementias attributable to smoking in 204 countries and territories, 1990–2021
Background Alzheimer’s disease and other dementias (ADD) are significant global public health challenges. Smoking is a clearly established modifiable risk factor for dementia. Objective This study a...
Neutropenic sepsis and septic shock in ICU patients: A single-center experience over the last decade
Purpose Sepsis and septic shock in patients with neutropenia are associated with high mortality. We investigated the features and outcome predictors of neutropenic sepsis in the last decade. Methods...
Convergence analysis of Suzuki’s generalized nonexpansive mappings using the Picard–Abbas iteration process
This manuscript investigates the convergence behavior of Suzuki’s generalized nonexpansive mappings using the recently introduced Picard–Abbas iteration process. We establish both weak and strong conv...
Return-to-work for people living with long COVID: A scoping review of interventions and recommendations
Introduction Long COVID is characterized by the presence of new onset or persistent symptoms 3 months after a suspected or confirmed history of SARS-CoV-2 infection. It is a complex and multi-faceted...
Computational modeling for enhanced reliability in space missions: An integrated FAHP-COPRAS approach to supplier selection
Liquid Crystal Displays (LCDs) are indispensable in space science, playing critical roles in spacecraft instrumentation, data visualization, and control systems. Selecting reliable suppliers for LCD e...
Feasibility and acceptability of research-grade wearables for health and labor capacity monitoring in the context of climate change and heat stress: The case of Nouna, Burkina Faso
Current climate projections estimate a further rise of mean ambient temperatures of 1.5°C until 2040. However, the understanding of heat stress’s impact on health and labor capacity, especially in vul...
A real-world pharmacovigilance analysis of acute renal failure associated with sacubitril/valsartan based on FDA Adverse Event Reporting System (FAERS)
Background The renal safety profile of sacubitril/valsartan remains debated in clinical practice. To address this uncertainty, we conducted a pharmacovigilance analysis of acute renal adverse events a...
Effects of woody plant encroachment on abundance of multiple tick species in the U.S. Great Plains
Vector-borne diseases are increasing in prevalence, posing a risk to 80% of the human population worldwide. In the United States, tick-borne diseases account for 75% of all nationally reported vector-...
Current and future burden of gynecological cancers attributable to high body-mass index: A comprehensive global analysis and projection study
Background High body-mass index (BMI) is a major modifiable risk factor for gynecological cancers, yet its contribution to the global cancer burden remains incompletely characterized. This study provi...
Key outcomes in treatment of activated phosphoinositide 3-kinase delta syndrome: An e-Delphi panel study and responder threshold application
Background Activated phosphoinositide 3-kinase delta syndrome (APDS) is an ultra-rare, underrecognized inborn error of immunity. This study aimed to identify outcomes important in evaluating APDS trea...
Suicide rates around Chinese and western valentine’s days in Taiwan: The roles of gender and marriage status
Background The suicide risk on Chinese Valentine’s Day and its potential risk factors have not been examined. This study assessed whether the suicide rates around Chinese and Western Valentine’s Days...
Unimproved source of drinking water and its associated factors: Multivariable analysis of Somalia Integrated Household Budget Survey (SIHBS 2022)
This study investigates the prevalence and factors associated with the use of unimproved drinking water sources in Somalia, a nation severely impacted by conflict, climate change, and a large nomadic...
Evaluation of GDH and HDP as novel serological biomarkers for Plasmodium falciparum malaria diagnosis across varying parasitemia and transmission settings in India
Malaria diagnosis has progressed significantly with the introduction of Rapid Diagnostic Tests (RDTs) targeting Histidine-Rich Protein 2 (HRP2), Lactate dehydrogenase (LDH), and aldolase. However, cha...
How to jointly control a ball trajectory on a moving board: Methodological insights into Motor Learning and Rehabilitation
Motor (re-)learning can be assessed using various conceptual and methodological frameworks, each of which portrays the learner’s abilities in different ways. The present paper investigates how the dir...
RETRACTED: Do natural environmental protection, regional innovation climate, entrepreneurs’ cognition of green development positively influence the sustainable development of small rural businesses
In the era of the green economy, the Chinese government has advocated for natural environmental protection and innovation in rural areas, making the sustainable development of small rural businesses i...
Mixed twitch and tetanus electrical stimulation via belt-electrode effectively attenuates denervation-induced muscle atrophy
Belt electrode skeletal muscle stimulation (B-SES) is a method of applying electricity to contract muscles using belt-shaped electrodes. We previously reported that twitch contractions increase mitoch...
Comparison of clinical characteristics and outcomes among different age groups in elderly patients with hip fracture surgery
Background Studies comparing the clinical characteristics and outcomes among different age groups in elderly patients with hip fractures are scarce. Thus, this study aimed to 1) analyze the clinical c...
Functions of coastal feeder bluff systems: Implications for prioritizing protection and restoration
Actively eroding cliffs, known as feeder bluffs, are important sources of sediment for coastal beaches. When shorelines have artificial armor, natural beach sediment processes can be disrupted. A rece...
Trends in Clostridioides difficile infection prevalence among pediatric cancer patients: A systematic review and meta-analysis
Introduction Pediatric cancer patients are highly susceptible to Clostridioides difficile infection (CDI) due to immunosuppression, prolonged hospitalization, and antibiotic exposure. This study deter...
STAG2 mutations in the normal colon induce upregulation of oncogenic pathways in neighbouring wildtype cells
While driver mutations in the normal colon have been described, characterizing the role and function of these driver mutations in relation to colorectal oncogenesis remains incomplete. Here, we invest...
Functional connectivity patterns of the Giant Toad Rhinella horribilis in anthropogenically modified landscapes
Anthropized environments often fragment native habitats and alter the movement of individuals across the modified landscape mosaic, which is significantly challenging for wild species. Deciphering the...
Oxidized dextran coated magnetic nanoparticles to develop magnetic cross-linked Bacillus lehensis G1 endolevanase aggregates for levan-type fructooligosaccharides synthesis
Endolevanase from Bacillus lehensis G1 (rlevblg1) is an enzyme that hydrolyzes levan for the production of levan-type fructooligosaccharides (L-FOS). To maximize the industrial utility of enzymes, it...
Association between mental health self-care status and well-being-promoting behaviors among university students living in rural areas
This study examined the relationship between the stages of behavioral changes related to mental health self-care and well-being (WB)-promoting behaviors. Students residing in a local city were invited...
Incidence and risk factors for phaeochromocytoma diagnosis in dogs under primary veterinary care in the UK
Phaeochromocytoma (PCC) is a tumour arising from the adrenal gland in dogs that can be challenging to diagnose. This study aimed to describe the incidence risk, breed predispositions and other demogra...
Defining high-risk pregnancy: Protocol for a systematic scoping review of clinical determinants, complications, and adverse birth outcomes
Introduction Accurately identifying clinical determinants within the medical paradigm is essential for evidence-based planning and management of high-risk pregnancies, and for preventing adverse birth...