PLoS ONE
Articles in this Issue
An affordable solution for investigating zebra finch intracranial electroencephalography (iEEG) signals
The zebra finch is a well-studied animal model for investigating the neural mechanisms of vocal learning, and electrophysiology is the primary technique for understanding their song system. Most of th...
Optimal gestational weight gain and pregnancy outcomes, by BMI and height, in a marginalised population of women with short stature living along the Thailand-Myanmar border: A retrospective cohort, 2004–2023
Background Existing gestational weight gain (GWG) standards may not be applicable to women of short stature and those who have limited access to healthcare and are vulnerable to compromised nutrition...
Drone thermal imaging and benthic time-series analysis show dynamic spatial and temporal delivery of submarine groundwater discharge on reef ecosystems
Submarine groundwater discharge (SGD) introduces nutrient-rich, low-salinity water into coastal ecosystems, significantly altering reef biogeochemistry. At Black Point, Oʻahu, we employed a novel, two...
Age and origin of a Cahokian wooden monument at the Mitchell site, Illinois, USA
Cahokia was the first and largest precolonial city outside of Mesoamerica in what is now the United States. Monuments and exotic goods were central to public life at Cahokia, but no high-resolution ti...
ICMR’s multistate implementation research study on integration of screening and management of mental and substance use disorders with other non-communicable diseases (ICMR-MINDS) – An implementation research study protocol
Non-Communicable Diseases (NCDs) are now a leading cause of mortality and morbidity globally, and mental illness is a significant part of it. In India, the treatment gap for common mental disorders is...
Extubation outcomes in critically ill post-craniotomy patients: A retrospective cohort study
Objective Extubation failure is common in critically ill post-craniotomy patients. This study aimed to assess extubation outcomes and examine demographic and surgical predictors of extubation success....
Effective image compression using transformer and residual network for balanced handling of high and low-frequency information
Image compression has made significant progress through end-to-end deep-learning approaches in recent years. The Transformer network, coupled with self-attention mechanisms, efficiently captures high-...
Midlife and old-age cardiovascular risk factors, educational attainment, and cognition at 90-years – population-based study with 48-years of follow-up
We examined the associations of midlife and old-age cardiovascular risk factors, education, and midlife dementia risk scores with cognition at 90 + years, using data from a population-based study with...
The impact of wildfires on the diet of Podarcis lusitanicus revealed by DNA metabarcoding
Fire has long been recognized as an important ecological and evolutionary force in plant communities, but its influence on vertebrate community ecology, particularly regarding predator-prey interactio...
Withdrawal: Astragaloside IV combined with quercetin attenuates silica-induced pulmonary fibrosis by promoting autophagy and suppressing pyroptosis
A new program for systematically enhancing cognitive reserve in healthy adults: A pilot randomized active-controlled clinical trial
Objective To evaluate the effectiveness of the Mental Training Tech 24.5 (MTT24.5) cognitive stimulation program, designed to enhance cognitive performance and neuroplasticity in healthy adults. Bac...
The decision uncertainty toolkit: Risk measures and visual outputs to support decision making during public health crises
Background During public health crises such as the COVID-19 pandemic, decision-makers relied on infectious disease models to evaluate policy options. Often, there is a high degree of uncertainty in th...
The rise in the contribution of denitrification is the primary reason for the increase of N2O emissions in the Anthropocene
Nitrous oxide (N2O) is the fastest growing category of greenhouse gases in the recent decades. This study systematically summarized the causes of increased N2O emissions and proposed targeted mitigati...
Post-pleistocene colonisation rather than the contemporary environment has most influenced the current population structure of Scottish Atlantic salmon (Salmo salar)
Genetic structuring in populations is the result of both historical and contemporary environmental factors driving genetic drift, natural selection and gene flow, as well as purely genetic factors, su...
Ecological suitability evaluation of traditional village locations in Jiangxi Province based on multi-model integration using artificial intelligence
Traditional villages have evolved over time to adapt to their environmental characteristics, demonstrating high ecological suitability. Ideal village locations not only provide comfortable living spac...
A blueprint of synergistic effect in Crataegus pinnatifida and obesity-related gut microbiota against obesity via systems biology concept
Background Current obesity treatments include behavioral interventions, pharmacotherapy and surgery. Recently, the combination of ‘medicinal food’ products such as the plant Crataegus pinnatifida and...
Prebiotic food intake and biochemical measures in diabetic patients: A cross-sectional study from the Sabzevar Persian Cohort
Background With the high prevalence of diabetes worldwide and the known benefits of functional foods in controlling diabetes, this study aimed to explore the connection between prebiotic food intake a...
Artificial intelligence literacy, sustainability of digital learning and practice achievement: A study of vocational college students
The rapid expansion of AI and the massive use of digital learning are creating a huge change in higher education. In contrast to general higher education, which is at the center of change, the changes...
Targeting vascular dementia: Molecular docking and dynamics of natural ligands against neuroprotective proteins
Vascular dementia (VaD), a neurodegenerative disease driven by vascular pathology, requires multi-targeted therapeutic strategies. This study employs an integrated in silico approach to evaluate the n...
Treatment and monitoring of a high-density population of bare-nosed wombats for sarcoptic mange
Sarcoptes scabiei causes a fatal disease (mange) in bare-nosed wombats (BNWs) (Vombatus ursinus) across their range and can threaten isolated populations with extinction. Repeated dosing of moxidectin...
Environment and weight class linked to skin microbiome structure of juvenile Eastern hellbenders (Cryptobranchus alleganiensis alleganiensis) in human care
Amphibian skin is integral to promoting normal physiological processes in the body and promotes both innate and adaptive immunity against pathogens. The amphibian skin microbiota is comprised of a com...
An investigation of the effects of different text formats on middle school students’ reading comprehension performance
This study is a quasi-experimental research that aims to compare the reading comprehension levels of students who read texts in textbooks through printed, digital, and augmented reality (AR)-supported...
Continuous or discrete magnitudes? A comparative study between cats, dogs and humans
A long-standing question in the study of quantity discrimination is what stimulus properties are controlling choice. While some species have been found to do it based on the total amount of stimuli an...
LncRNA RP11-818O24.3 regulates proliferation and differentiation of hair follicle stem cells by targeting FGF2/PI3K/AKT pathway
Hair follicle stem cells (HFSCs) play critical roles in adult hair regeneration, owing to its self-renewal and multipotent differentiation properties. Emerging evidence has shown that long noncoding R...
Seeking validation in the digital age: The impact of validation seeking on self-image and internalized stigma among self- vs. clinically diagnosed individuals on r/ADHD
The digital age has fueled a surge in ADHD self-diagnosis as people turn to online platforms for mental health information. However, the relationship between validation-seeking behaviors and self-perc...