PLoS ONE
Articles in this Issue
The impact of anodization modification on titanium interaction with human osteoblasts and fibroblasts (in vitro study)
Title The impact of new anodization modification on titanium interaction with human osteoblasts and fibroblasts (in vitro)...
Per- and polyfluoroalkyl substances (PFAS) in fish collected from the Rio Grande and reservoirs in northern New Mexico
Per- and polyfluoroalkyl substances (PFAS) are a group of industrial and commercial chemicals widely used throughout the world due to their beneficial chemical properties. Because of their widespread...
Functional characterization of a bovine luteal cell culture model: Effects of passage number
Primary cell culture models are useful tools to analyze intracellular signaling pathways and interactions in detail. However, at higher passages, vital cell characteristics such as cell morphology, ph...
Temporal dynamics of emotional face processing in social anxiety
Previous studies have demonstrated that emotional facial expressions influence attention and perception in individuals with social anxiety. However, the relative influence of positive versus negative...
Parasites of the hermit crab Pagurus hirsutiusculus; distribution, prevalence, and thermal ecology
Parasites are common throughout the biosphere and can play significant ecological roles. However, most parasites are understudied, particularly with regards to how their prevalence and impacts vary wi...
Development of the advised protocol for OCT study terminology and elements anterior segment OCT extension reporting guidelines (APOSTEL-AS): Study protocol
Background Anterior segment optical coherence tomography (AS-OCT) is emerging as a valuable diagnostic, monitoring and predictive tool. Clinical utility has been suggested for opht...
Assessment of clinical medical education needs inform design of a preceptor development program in Jordan: A multi method study
Background Clinical preceptors serve as vital educators, so it is essential to enhance their effectiveness by developing a competency-based development program. In this study, we e...
MetaGradient driven strategy decomposition for accelerated equilibrium in large scale logistics networks
Static models fail to track the fast-changing supply-demand balance in global logistics. For instance, the high-speed rail express corridor exhibits a transport capacity utilisation rate of less than...
CXCL3 promotes liver cancer progression by modulating the tumor microenvironment via the PI3K/AKT/mTOR pathway
CXCL3, a member of the CXC chemokine family, has been increasingly implicated in the progression of various cancers, including hepatocellular carcinoma, due to its role in immune and inflammatory resp...
Safety assessment of cyclin-dependent kinase 4/6 inhibitors and comparison of time to adverse events
Background Multiple CDK4/6 inhibitors have been approved for the treatment of HR + /HER2- advanced breast cancer. Nevertheless, there is currently a scarcity of safety reports on C...
Early enteral nutrition and mortality in mechanically ventilated septic patients receiving vasopressors: A retrospective cohort study using the MIMIC-IV database
Background The role of early enteral nutrition (EEN) in septic shock remains unclear. This study aimed to evaluate the association between EEN and clinical outcomes in septic patie...
Reinforcing intensive motherhood: A study of gender bias in parental responsibilities allocation by large language models
This study investigated gender bias in Large Language Models (LLMs) within the context of parenting responsibility attribution, focusing on whether LLMs implicitly reinforce the ideology of “intensive...
The percentile-matching technique for synthetic eye tracking signal degradation: A biometric case study
This manuscript demonstrates an improved model-based approach for synthetic degradation of pre-recorded eye movement signals. Recordings from a high-quality eye tracking sensor are transformed to make...
Investigating the impact of type I-E CRISPR-Cas systems and acrEI10 on multidrug-resistance in clinical isolates of Klebsiella pneumoniae
Klebsiella pneumoniae is a pathogen related to nosocomial infections with a high rate of antibiotic resistance. The aim of this study was to understand the impact of the presence o...
Identification of pathogenic variants for the development of ultra-long axial length in myopic children
Purpose Axial elongation is a key factor in myopia progression, yet its genetic basis remains incompletely understood. This study aims to identify pathogenic genetic variants assoc...
Promises and pitfalls of using LLMs to identify actor stances in political discourse
Empirical research in the social sciences is often interested in understanding actor stances; the positions that social actors take regarding normative statements in societal discourse. In automated t...
Patient survival and kidney transplantation in different dialysis modalities under PD First Policy Thailand
Background Thailand implemented a peritoneal dialysis (PD)-first policy under its universal health coverage (UHC) from 2008 to 2022. This study aims to describe patient survival du...
The impact of physical exercise on adolescents’ social-emotional competence: The chain mediating role of social support and peer relationships
This study aims to explore the relationship between physical exercise and adolescents’ social-emotional competence, and analyze the chain mediating effects of social support and peer relationships. Da...
Objective scoring of application forms in obstetrics and gynaecology residency selection: A retrospective cohort study on the optimal number of committee members
Introduction The selection of residents for medical specialty programmes is a critical yet resource-intensive process. Although structured evaluation tools, such as standardized ap...
Whole genome sequencing, characterization and analysis of coronene degrading bacterial strain Halomonas elongata
Polycyclic aromatic hydrocarbons (PAHs) are persistent environmental pollutants with significant ecological and health risks. Among them, coronene, a high molecular weight PAH, is particularly resista...
Correction: An efficient hybrid reliability analysis method with application to the harmonic drive
A study protocol for the assessment of antibiotic use and bacterial antimicrobial resistance among children under five years of age: Implications for a resource-limited setting
Background The irrational use of antibiotics to treat infections in children is a crucial contributing factor to bacterial antimicrobial resistance (AMR), which can have economic a...
Warburg-Cinotti disease variant p.Tyr740Cys enhances catalytic activity of DDR2 kinase
The discoidin domain receptor DDR2 is a collagen-binding receptor tyrosine kinase whose dysregulation is associated with a wide range of diseases. Missense mutations in the DDR2 kinase domain cause Wa...
Iterative reconstruction of industrial positron images with generative networks
Positron imaging has shown great potential in industrial non-destructive testing due to its high sensitivity and ability to reveal internal structures of complex components. However, reconstructing hi...
Global, regional, and national burdens of late-onset epilepsy in adults aged 65 years and older from 1990 to 2021: A population-based study
Objective Epilepsy remains one of the most widespread and severe neurological disorders worldwide. This study aims to evaluate the burden of late-onset epilepsy (LOE) and investiga...