PLoS ONE
Articles in this Issue
Minimally invasive steam-assisted drug delivery with ICG fluorescence guidance for primary malignant bone tumors and evaluation of clinical applicability
Background Malignant bone tumors are rare cancers with a poor prognosis, often causing severe pain and pathological fractures that substantially reduce patients’ quality of life. C...
Serum IgG titer findings for Fusobacterium nucleatum associated with clinical outcome following surgery in patients with esophageal squamous cell carcinoma
Fusobacterium nucleatum ( Fn ) is known as an etiological factor related to periodontitis. However, recent reports have shown that it also f...
Impact of a tropical monsoon climate on formaldehyde exposure and microbial contamination in anatomy dissection hall
Gross anatomy dissection is an essential component of medical and health science education, yet it presents notable occupational hazards, particularly from formaldehyde (FA) exposure and microbial con...
Relationships between growth mindsets and math achievement across socioeconomic status in 74 countries: Evidence from PISA 2022
Growth mindsets have gained attention from education stakeholders due to their potential to enhance academic outcomes. However, some studies found that the relationship between mindsets and student ac...
A plasma-based protein signature association with all-cause mortality
Circulating plasma proteins play key roles in measuring and reflecting states of disease and health. Developments in protein metrology allow for over 2,900 proteins to be quantified in a single sample...
Factors affecting women’s nutritional security in rural Bangladesh: The role of livestock and other socioeconomic characteristics
In every household, women play a crucial role in shaping the foundation of food and nutrition. They are primarily responsible for ensuring nutritional security for all members. However, women often fi...
Readiness of health posts to manage child wasting in six districts of Ethiopia
Background Service readiness is essential for providing effective health services. Adequate infrastructure, trained staff, and essential commodities must be in place to enable time...
The double helix model: Dynamic evolution of knowledge absorptive capacity and innovation efficiency
This study aims to propose a “double helix” dynamic evolution model of absorptive capacity and innovation efficiency, breaking through traditional linear cognition and revealing the synergistic growth...
Unpacking equity trends and gaps in Nepal’s progress on maternal health service utilization: Insights from the most recent Demographic and Health Surveys (2011, 2016 and 2022)
Background Improving maternal health is a global priority for overall socioeconomic development countries, especially in the low- and middle-income countries including Nepal. Recen...
Prevalence and determinants of under-five mortality (U5M) in low-and lower -middle-income countries: Evidence from recent demographic and health surveys
Objectives Under-five mortality (U5M) remains a major global challenge, particularly in low-and lower-middle- income countries (LLMICs) where healthcare disparities are prevalent....
Research on synchronous load control of shield beam for 50,000 kN hydraulic support test bench
This paper proposes an innovative synchronous load control system for protective beams, addressing the issues of uneven loading and asynchronous positioning in dual-cylinder loading systems during hyd...
Global HIV prevention, treatment, and care interventions and strategies for key populations: Protocol for a scoping review
Introduction Since its emergence, HIV/AIDS has remained one of the most significant global health challenges, with key populations—such as sex workers, men who have sex with men (M...
Coupled-oscillator-humanizer revealed possible ensemble players’ ability to discriminate cross-correlation structures in auditory sequences of paired drum tapping
Natural fluctuations in the timing sequence are essential for a dynamic and expressive rendition of music. Various studies have demonstrated the statistical structure of such timing fluctuations in so...
Microstructure and performance of laser cladding 17-4PH-xTiC coatings on harvester blades
To address the need for extending the service life of combine harvester blades, this study employs laser cladding technology to prepare 17–4PH-xTiC coatings with varying TiC content on 65Mn steel subs...
Effect of guided dual-sensory information on motor learning outcomes based on spatiotemporal dimensions
The effectiveness of instructional information is crucial to enhancing motor learning outcomes. However, few studies have explored the mechanisms of augmented attention-guiding dual-sensory informatio...
Birth month as a risk factor of allergic diseases: Analysis of database of about 50 thousand children
Background The season of birth is a factor influencing the child during the neonatal adaptation period and potentially affecting the risk of allergies. The objective of this study...
Concern for severe COVID-19 disease during the initial two years of pandemic in a rural South African community: A population-based study
Background Globally, as of December 2023, over 700 million cases of COVID-19 were confirmed since the initial outbreak late in 2019, claiming around 7 million lives and fuelling wi...
Safety and efficacy of radiotherapy combined with immunotherapy in limited-stage small cell lung cancer a single-arm meta-analysis and systematic review
Background Limited-stage small cell lung cancer (LS-SCLC) has a poor prognosis despite being potentially curable with standard concurrent chemoradiotherapy. The success of immune c...
How does general and specific human capital drive technology development in firms?
This paper examines the extent to which human capital within a firm is associated with technology development. We develop and apply an original and more objective measure of technological advancement...
Novel archaeological and palaeontological findings in cave and palaeoriver landscapes of inland northeast Arabia
Knowledge about environmental change and the evolutionary history of hominins in Arabia has been rapidly developing over the last two decades. Interdisciplinary research on humans and environments acr...
Combined effects of gliding-arc plasma and C-phycocyanin on antioxidant activity and shelf-life extension of rainbow trout (Oncorhynchus mykiss) fillets
The study aimed to evaluate the impact of gliding arc plasma (GAP) treatment and phycocyanin pigment (PCP) on the antioxidant activity and refrigerated shelf-life extension of Onco...
Omicron surge impact on acute kidney injury in ICU patients: A study using the ISARIC COVID-19 database
Background Acute Kidney Injury (AKI) is common among COVID-19 patients and is associated with a higher risk of death. Compared to earlier COVID-19 variants, Omicron has reduced mor...
Characterization of alveolar epithelial cells type II during postnatal lung development in relation to alveolarization – Stereological studies of rat lungs
Objective Rats are born with morphologically immature lungs, but intact surfactant system. The aim of this study was to characterize the surfactant producing alveolar epithelial ce...
Unequal expression: Social position modulates APOE genotype risk of dementia
Background Although social position plays a pivotal role in cognitive aging, most dementia prevention strategies and risk prediction models continue to emphasize biomedical and gen...