PLoS ONE
Articles in this Issue
Stay or go? Exploring physician turnover in European Hospitals–Evidence from the METEOR survey
According to the World Health Organization (WHO), in 2022 there was a shortfall of approximately 1.2 million doctors, impacting healthcare system and patient care. Understanding turnover intentions is...
Geographically weighted regression analysis of incomplete basic childhood vaccination in Sub-Saharan Africa: Evidence from DHS, 2019–2024
Background Immunization is the safest way to protect against disease. Currently, vaccination saves more than 4 million lives annually. By 2030, 90% of people worldwide are expected...
Understanding merger control remedies in China
We identified 8 merger cases with remedies in China for a period from the time when the Anti-monopoly Law was enacted in 2008–2018, and about 150 other merger cases corresponding to these 8 cases in t...
Structured matching models in multimodal information fusion: An optimized Kuhn-Munkres algorithm
In modern multimodal interaction design, integrating information from diverse modalities—such as speech, vision, and text—presents a significant challenge. These modalities differ in structure, timing...
Joint angle trajectories are Robust to segment length estimation methods in human reaching
Background Quantitative movement analysis is increasingly used to assess motor deficits, but joint angle calculations depend on assumptions about limb segment lengths. These length...
Evaluation of a “one-stop shop” for integrated harm reduction and primary care for people who inject drugs
Background People who inject drugs (PWID) experience high risk for HIV and HCV infection, which can be mitigated by harm reduction strategies, including syringe service programs (S...
Single-cell RNA sequencing reveals the role of immunoinflammatory cells in the progression of renal tubulointerstitial fibrosis
Renal tubulointerstitial fibrosis (TIF) is an independent risk factor for chronic kidney disease (CKD) progression and prognosis. It is known that immunoinflammatory cell infiltration plays a crucial...
Comparison of lower limb muscle activation between slow and fast tempos during the stepping test in young men
The aim of this study was to determine whether and which lower limb muscles contribute to maintaining dynamic balance during the stepping test. Twelve healthy young men performed in-place stepping at...
Development and validation of ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method to quantify monotropein in blueberries
Blueberries ( Vaccinium species) are an economically important fruit crop rich in bioactive compounds like polyphenols and flavonoids. Interestingly, some blueb...
An auditory-visual cooperative perception method for honking vehicle localization
Locating honking vehicles is crucial for controlling arbitrary honking and reducing environmental noise. However, traditional methods for honking vehicle localization, which utilize sound source local...
Navigating productivity dilemmas and conflicting loyalties in activity-based flexible offices - A qualitative study of managers’ perspectives and coping strategies
Activity-based Flexible Offices (AFOs) provide employees with a variety of workspaces to choose from based on their tasks, rather than having assigned desks. While the adoption of AFOs is increasing d...
One step synthesis of ultrafine PHF@AuNPs nanocomposite and its application in NIR triggered photodynamic therapy
Photodynamic therapy (PDT) is a rapid advancing treatment for cancer therapy. The main challenges in PDT include poor absorption in the “tissue optical window” and aggregation tendency of photosensiti...
GaneStat—A comprehensive design and modular analysis of portable, low-cost, and high-accuracy potentiostat
Electrochemical research has been developing with the advancement of laboratory equipment and sophisticated technologies. One of which is the portable potentiostat, which has been utilized to analyze...
Large language models for prognostic analysis in mechanical fault diagnosis
With the in-depth development of industrial intelligence, as the core basic component of high-end equipment, the fault diagnosis and health management of rotating machinery has become a key link to en...
Short-term impact of preschool sound exposure on outer hair cell function in young children: An analysis using pressurised distortion product otoacoustic emissions
Background Preschool children are regularly exposed to high noise levels that may affect hearing. A previous study has linked preschool noise exposure to reduced distortion product...
Circulating microRNAs as biomarkers for diabetic retinopathy stage identification: A DTA systematic review and meta-analysis
Purpose To evaluate the diagnostic accuracy of circulating miRNAs in distinguishing between different diabetic retinopathy (DR) stages in type 2 diabetes mellitus (T2DM)....
Advanced electrochemical biosensing of pathogens: Harnessing the antimicrobial properties of Ib-M peptides for highly sensitive bacterial detection
This study describes the development of electrochemical biosensors with high sensitivity to detect pathogenic bacteria, including Escherichia coli O157:H7,...
Random rotational embedding Bayesian optimization for human-in-the-loop personalized music generation
Generative deep learning models, such as those used for music generation, can produce a wide variety of results based on perturbations of random points in their latent space. User preferences can be i...
Inhibition of NF-κB pathways alleviates hydrocephalus via modulation of choroid plexus epithelium inflammation in a rat intraventricular hemorrhage model
Backgrounds Post-hemorrhagic hydrocephalus (PHH) is a serious complication following hemorrhagic events due to cerebrospinal fluid (CSF) pathway disorders. We explore the Nuclear F...
Exploring the link between AI usage intention and digital competence among college PE teachers: A moderated mediation model based on SCT and UTAUT
As artificial intelligence (AI) technologies rapidly integrate into higher education, they impose increasing demands on the teaching approaches and digital competence of physical education teachers. H...
Synergistic effects of proteinaceous pheromone and nitrogen starvation on male gametogenesis in the anisogamous volvocine alga Eudorina
In volvocine algae, gametogenesis is triggered by different cues depending on the species and their sexual systems. In isogamous unicellular organisms such as Chlamydomonas reinhar...
Fundamental motor skills, executive functions, and academic achievement of Chinese schoolchildren: Testing a mediating model
Background Researchers have observed the relationship between children’s fundamental motor skills (FMS) and their academic achievement. However, the inner workings of this correlat...
Clinical impact of prophylactic antibiotics in kidney transplantation: A retrospective observational cohort study with historical comparison
Purpose Optimal perioperative antibiotic prophylaxis in kidney transplantation remains undefined despite routine antibiotic administration to prevent infections. In this retrospect...
Utilization of tetanus and diphtheria serology tests in Alberta, Canada: Patterns and implications
Background Tetanus and diphtheria (Td) antibody titers can be measured to assess for seroprotection from immunization, though this is not routinely indicated. There are limited pop...
Perceived safety and mental health among Asian American women: Exploring the moderating role of loneliness and resilience
Asian American women are an understudied population facing a substantial mental health burden, largely driven by the increasing rates of gender- and race-based violence and discrimination. Perceived s...