PLoS ONE
Articles in this Issue
Retraction: Endometriosis and pregnancy: The illusion of recovery
Antibiotic dispensing behaviors for pediatric diarrhea: A qualitative study of informal healthcare providers in rural Bangladesh
Antibiotic resistance is a significant public health concern and requires coordinated efforts to promote antibiotic stewardship. In rural Bangladesh, informal healthcare providers known as “village do...
The reciprocal relationship between non-alcoholic fatty liver disease and hypothyroidism: A systematic review and meta-analysis of about 39 million individuals
Background Non-alcoholic fatty liver disease (NAFLD) and hypothyroidism are both prevalent conditions with potential reciprocal influences. This study evaluates the link between NA...
Do government subsidies lead to TFP losses? A perspective on the formation of zombie firms
This study examines how government subsidies affect aggregate total factor productivity (TFP) through the formation of zombie firms in China. Using panel data of A-share listed firms from 2007 to 2022...
The hidden risks of polypharmacy: Exploring potentially inappropriate prescribing with STOPP/START criteria version 3–A cross-sectional study
Polypharmacy and inappropriate prescribing are critical challenges in geriatric medicine, leading to adverse drug reactions, hospitalizations, and increased healthcare costs. The updated STOPP/START v...
Effect of creep-feeding supplementation during the pre-weaning phase on gene co-expression in Longissimus thoracis muscle of F1 Angus x Nellore calves at weaning
The aim of this study was to analyze gene co-expression in skeletal muscle of calves with or without creep-feeding during the pre-weaning phase. Forty-eight F1 uncastrated male Angus-Nellore calves we...
Efficacy and safety of Atezolizumab plus Bevacizumab and Lenvatinib as first-line systemic therapies for hepatocellular carcinoma: A real-world study
Atezolizumab plus bevacizumab (ATEZO/BEV) and Lenvatinib (LEN) have demonstrated efficacy as first-line systemic therapies for unresectable hepatocellular carcinoma (HCC). This study aimed to compare...
OntoSecAI: Ontology-driven security automation for AI-enabled systems
The advent of artificial intelligence (AI) models presents significant opportunities alongside inherent security risks, such as the exploitation by adversaries generating malicious data to compromise...
Transgender and gender diverse autistic adults’ experiences of (un)belonging
Introduction Clinical impressions suggest a significant overlap of autistic as well as transgender and gender diverse identities, implying a need for research that explores TGD aut...
Characterizing proximal risk for depressive symptoms and suicidal ideation with acute cannabis use and withdrawal among adolescents using ecological momentary assessment: Study protocol
Background Heavy cannabis use often co-occurs with symptoms of depression in adolescents. Adolescents with past-year cannabis use are at increased risk of major depressive episodes...
Analysis of molecular mechanism of Chinese medicine Jinhong decoction (JHD) in synergistically treating sepsis and COVID-19 based on network pharmacology
Sepsis and COVID-19 are the two mutually-reinforcing risk factors, whose interaction drastically increases mortality rate. Jinhong decoction (JHD) as a Chinese medicine exhibits clinical efficacy agai...
Study on the damage and failure behavior of coal exposed to acid corrosion under impact load
The depth of coal mining is continuously increasing. In the process of deep underground coal mining, the hydrological conditions of coal seams are complex, with some coal seams subjected to corrosion...
From cervix to multisite: Detection of lower genital tract lesions in a 10-year cross-sectional colposcopy clinic study
Objective To evaluate detection rates of multisite lesions (cervical, vaginal, vulvar) among women attending colposcopy clinics....
Retraction: Kidney damage on fertility and pregnancy: A Mendelian randomization
Real-world safety of Tepotinib: Insights from the Food and Drug Administration Adverse Event Reporting System
Objects Tepotinib is widely utilized for treating non-small cell lung cancer (NSCLC) patients with MET exon 14 (METex14) skipping mutations. The purpose of this study is to evaluat...
Analysis of risk factors for postoperative complications in hypospadias and construction and validation of a nomogram predictive model
Background The incidence of postoperative complications in children with hypospadias is notably high; however, research on predictive models for these complications remains limited...
Impact of Metformin therapy on miR-9, miR-223, and miR-132 and inflammasome-related gen expression in obese and non-obes PCOS patients: A comparative study with healthy controls
Introduction Polycystic Ovary Syndrome (PCOS) is a common endocrine and metabolic disorder characterized by chronic inflammation, insulin resistance, and hor...
The Nurses’ Innovative Behavior Inventory (NIBI): A development and validation study
Introduction Innovative behavior is essential in nurses, driving continuous improvement and operational efficiency, significantly enhancing patient outcomes and overall healthcare...
Visual prediction of outcomes in patients undergoing intravenous thrombolysis
Background This research presents a novel visual predictive model aimed at the early identification of patients at elevated risk of poor prognosis following intravenous thrombolysi...
Retraction: Choosing the most appropriate minimally invasive approach to treat gynecologic cancers in the context of an enhanced recovery program: Insights from a comprehensive cancer center
The effect of the modifiable areal unit problem on ecological model inference: A graphical simulation study for disease mapping in Australia
Statistical disease mapping is a valuable public health tool, as it identifies spatial patterns of disease occurrence. However, the Modifiable Areal Unit Problem (MAUP) poses challenges to disease map...
Cerebellar functional connectivity alteration in individuals with lower limb amputation
Limb amputation triggers a reorganization of brain structure and function. Previous research using neuroimaging techniques, such as resting state functional magnetic resonance imaging, indicates reduc...
The role of lifestyle in mitigating cognitive decline in older adults with cardiometabolic multimorbidity (CMM): A protocol of systematic review and meta-analysis
Background Cardiometabolic multimorbidity (CMM), the coexistence of two or more cardiometabolic diseases (CMDs), is increasingly recognized as a key risk factor for cognitive decli...
Clinical features and pulmonary infections of diffuse alveolar hemorrhage in rheumatic disease patients
Introduction Diffuse alveolar hemorrhage (DAH) is an uncommon but potentially life-threatening pulmonary complication in patients with rheumatic diseases (RD). Immunosuppression, e...
Burden of liver cancer resulting from different etiologies in China from 1990 to 2021 and prediction to 2031
Liver cancer (LC) imposes a considerable disease burden in China, with diverse causes contributing to varying proportions of LC cases. Adjusting future public health strategies for the allocation of r...