PLoS ONE
Articles in this Issue
Contrasting effects of DNA demethylation on cancer-germline gene expression in breast cancer and leukemia cells
Human germline gene expression is normally constrained to the germ cells, responsible for the production of sperm and oocytes. Cancer-germline (CG) genes, a subset of germline genes involved in testis...
Expression of Concern: Uterine leiomyoma is associated with the risk of developing endometriosis: A nationwide cohort study involving 156,195 women
Genomic and enzymatic insights into α-amylase-producing Bacillus spizizenii strains isolated from Isfahan province, Iran
Objective α-Amylases represent a class of industrially critical enzymes widely employed in food processing, animal feed, and biotechnology sectors. While mic...
Correction: A GAN-Based Approach for enhancing security in satellite based IoT networks using MPI enabled HPC
Simulation and symbolic thinking in equations representing change
Learning simulations can enhance conceptual understanding in numerous education contexts, like physics, chemistry, ecology, and more. This conceptual understanding is often expressed symbolically usin...
Distribution of pediatric intensive care beds in Brazil: Regional inequalities and implications for equity in the public health system
Background Pediatric Intensive Care Units (PICUs) play a critical role in reducing child mortality, but their distribution across Brazil remains markedly uneven. Understanding how...
Expression of Concern: Contribution of labor related gene subtype classification on heterogeneity of polycystic ovary syndrome
High-resolution biomechanical mapping of SMILE and SMILE with CXL using Brillouin microscopy: Insights into localized corneal stiffness preservation
Purpose To evaluate the biomechanical effects of small incision lenticule extraction (SMILE) alone and with corneal collagen cross-linking (SMILE...
30-day survival and injury severity in traffic accidents in Iran: A mixed-method study protocol
Background Today, one of the greatest global challenges, particularly in developing countries, is traffic accidents and their associated consequences. The severity of injuries from...
Correction: Synthesis of novel phenoxyacetohydrazide compounds and evaluation therapeutic potential exhibit as anti-inflammatory and anti-angiogenic
Expression of Concern: An international consensus for mitigation of the detrimental effects of the COVID-19 pandemic on laparoscopic training
Retraction: The yield of procalcitonin and Interleukin-6 in predicting intraamniotic infection in the presence of intrapartum fever: A pilot study
Co-isolation of genetically distinct Burkholderia pseudomallei strains from a single patient in North Queensland
While investigating colony morphology variation within clinical isolates of Burkholderia pseudomallei ( Bp) isolated fro...
Policy innovation of construction waste management in Xi’an, China: A SWOT analysis of incentive mechanisms
This study uses Xi’an as a case to explore incentive mechanisms and optimization pathways in construction waste management. Drawing on policy text analysis, semi-structured interviews, and the Delphi...
Hospital unit working conditions and risk for employee injury
Background Healthcare employees, particularly in pediatric hospitals, are at high risk of occupational injuries. However, few studies have examined hospital unit-level factors that...
Expression of Concern: Utilization of complementary and alternative medicine (CAM) by women with breast cancer or gynecological cancer
Effects of hip abducted position during eccentric-only resistance exercise on acute changes in passive stiffness of the biarticular hamstring muscles
Recent studies have revealed that eccentric-only resistance exercise has the potential to acutely decrease passive stiffness of some biarticular hamstring muscles. The biarticular hamstring muscles ar...
Athlete maltreatment in sport: Protocol for a scoping review
Research on maltreatment in sport demonstrates detrimental effects on athletes’ well-being, and recent news reports highlight the pervasiveness of this issue. However, inconsistencies in defining and...
Geospatial modeling and forecasting of urban land use change using Google Earth Engine and machine learning
Urban expansion and Land Use Land Cover (LULC) change pose critical challenges for sustainable urban planning and risks to food security. This study analyzes multi-temporal Landsat imagery from 1990 t...
Anatomical mapping and quantitative functional analysis of lower limb lymphatic flow in normal cynomolgus monkeys using indocyanine green lymphography
Background The lymphatic system is essential for fluid balance and immune regulation, but its anatomy and function in translational models remain insufficiently defined. Indocyanin...
Agent-based modelling reveals feedback loops and non-linearity between mating system evolution and disease dynamics
Despite its potential for providing a deeper understanding of both evolutionary processes and epidemic dynamics, the reciprocal interrelationship between mating system evolution and sexually transmitt...
Retraction: Role of Vitamin-D Receptor (VDR) single nucleotide polymorphisms in gestational hypertension development: A case-control study
Retraction: Clinical implications of first-trimester ultrasound dating in singleton pregnancies obtained through in vitro fertilization
OpenIDS2: A low-cost, 3D-printed, open-source platform for reproducible construction of DNA microarray synthesizers
Oligonucleotide synthesis is a fundamental technology in various fields of life science, including synthetic biology, molecular diagnostics, and biotechnology. In this study, we present OpenIDS2, an o...
Proteomic screening of TMEM43 binding partners identifies VDAC leading to mitochondrial dysfunction
The transmembrane protein 43 (TMEM43) S358L mutation is the most common mutation found in patients with ARVC5, a severe subtype of arrhythmogenic right ventricular cardiomyopathy (ARVC). Characterizin...