PLoS ONE
Articles in this Issue
The effectiveness of Question Prompt Lists (QPL) in enhancing treatment outcomes for cancer patients among tribal population in Meghalaya: A quasi-experimental design
Background Cancer remains a leading cause of death worldwide, with a significant burden in India’s northeastern states, including Meghalaya. Patients from tribal communities often...
Motor function tests as early indicators of cognitive and functional decline in older adults: A correlational study
Objectives This study aimed to explore the relationship between selected motor performance tests and indicators of cognitive impairment in older adults. Specifically, it examined a...
Identification of diagnostic and prognostic biomarkers for tuberculosis based on plasma proteomics
Background The differential diagnosis between Tuberculosis (TB) and Non-tuberculous Mycobacteria (NTM) has historically been constrained by the inadequate sensitivity and specifici...
Diagnostic accuracy of the TrueNat™ MTB plus assay for detecting pulmonary tuberculosis in adults
Tuberculosis (TB), caused by Mycobacterium tuberculosis remains a global threat, affecting 10.8 million people and causes 1.3 million deaths annually. Over 2.5...
Modelling and improving approach for carrying capacity in multi-modal super network by considering travel time
For the sake of achieving the mensuration of network carrying capacity under regular even congested road conditions with crowded vehicles, passengers or cyclists in a median-scale network, this study...
Variability of a job search indicator induced by operationalization decisions when using digital traces from a meter
Digital traces —particularly metered data—offer researchers a valuable alternative to surveys for studying online behavior. However, because the concepts being measured are not directly observable in...
Bioactive fungal metabolites as SIRT2 antagonists: A computational quest for cancer treatment
SIRT2, a member of the sirtuin protein family, plays a pivotal role in regulating tumor progression by modulating key metabolic pathways and signaling proteins. The regulatory role of this protein has...
Perceptual discrepancies in the experience and reporting of violence against children are more pronounced among social workers compared to laypeople
When violence against a child is reported to authorities, it is crucial that its severity is communicated effectively and evaluated accurately by professionals. This study, conducted in two phases, in...
Indoor location perception model based on Resnet50 and Elman network
The visible light indoor position perception method not only solves the limitations of traditional positioning technology indoors, but also promotes innovation in fields such as smart retail and healt...
Correction: Defining a need for rapid response and practical guidance for recurrent and metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) management in France: A Delphi consensus
Sex disparities in adult obesity prevalence across 47 African countries: A cross-sectional descriptive study
Background Obesity is a growing public health concern in Africa, with evidence suggesting pronounced disparities between men and women. Understanding the prevalence and sex differe...
Correction: Phyllostachyos Caulis in Taeniam extract stimulates longitudinal bone growth via IGF-1 and JAK2/STAT5 signaling in rats
Correction: Mathematical analysis of the dynamics of cyberattack propagation in IoT networks
Enhancing network traffic detection via interpolation augmentation and contrastive learning
With the rapid advancement of information technology, the Internet, as the core infrastructure for global information exchange, faces increasingly severe security challenges. However, traditional netw...
Cannulation-related wound complications after extra corporeal life support: A retrospective cohort study in a Dutch intensive care unit
Extracorporeal life support (ECLS) is a high-risk therapy for acute cardiac or respiratory failure. After weaning, wound healing at the cannulation site is often disrupted, leading to discomfort, dela...
The bilirubin-to-albumin ratio as a potential prognostic biomarker for all-cause mortality in patients with acute decompensated cirrhosis: A prospective study
Background Acute decompensation (AD) of liver cirrhosis is a life-threatening condition with high mortality and a significant healthcare burden. Although various prognostic models...
Abundance of bacteria and histopathologic findings in the small intestinal mucosa of dogs with chronic inflammatory enteropathies
Chronic inflammatory enteropathy (CIE) is often retrospectively classified as food-responsive, steroid-responsive, and antibiotic-responsive enteropathy. However, whether bacterial fluorescence...
Correction: Gene electrotransfer with flow-through microchannel and lower alternating voltage generated induced pluripotent cells from human lymphoblastoid cell lines
Key soil properties governing Cr(VI) retention in 16 natural soils: A comprehensive geochemical and statistical analysis
Hexavalent Chromium (Cr(VI)) contamination in soils poses significant ecological risks due to its mobility and toxicity, with retention mechanisms governed by interactions between soil properties and...
Genetic monitoring of a long-term, large-scale experimental steelhead supplementation program
Declining salmonid populations often prompt the use of captive-reared fish to supplement wild stocks, but such programs risk negative genetic and ecological impacts. We evaluated six steelhead (...
Discovery of F-18 labeled repurposed CNS drugs by computational strategy for effective tau imaging and alzheimer’s diagnosis
Alzheimer’s disease (AD) remains a significant challenge in diagnosis and treatment, with current methods insufficient for early detection. A major obstacle is the lack of effective imaging agents tar...
Mechanical response design of arch seat foundation under complex traffic loading
The mechanical response of the arch seat foundation of extra-long-span arch bridges under complex traffic loads has not been fully understood. To address this gap, this study develops a field-scale th...
Ratio maps of T1w/T2w MRI signal intensity do not improve deep-learning segmentation of pediatric brain tumors
Introduction T1w/T2w ratio mapping, combining voxel-wise signal intensities in T1-weighted (T1w) and T2-weighted (T2w) structural MRI, has been used to investigate cortical archite...
General practitioners’ experiences of managing low back pain in primary care in Ireland: A qualitative phenomenological study
Background Low back pain (LBP) is one of the most common symptoms presented in general practitioner (GP) consultations worldwide and is a leading cause of disability. Despite LBP c...
Breeding seasonality of Tylopoda: Expected patterns in Old World camelids but an exceptional pattern in South American camelids
Seasonal breeding is a common adaptation among mammals in seasonal environments, ensuring offspring is born under favourable conditions. As only conception can be controlled but not birth itself, a pr...