PLoS ONE
Articles in this Issue
Microbiota discovered in scorpion venom
With low nutrient availability and presence of numerous antimicrobial peptides, animal venoms have been traditionally considered to be harsh sterile environments that lack bacteria. Contrary to this a...
Functional role of THRAP3 in modulating thyroid hormone–mediated gene networks in C2C12 myotubes
Thyroid hormone (TH) secreted by the thyroid gland plays essential roles in regulating metabolism, development, and nervous system function. Thyroid hormone receptor-associated protein 3 (THRAP3) is a...
Correction: Performance enhancement and PAPR reduction for MIMO based QAM-FBMC systems
Shifting epidemiological patterns and strain replacement of hand, foot, and mouth disease in southern China, 2009–2022: A longitudinal study
Background China launched a universal campaign of monovalent-inactivated EV-A71 vaccine in 2016. However, the monovalent-inactivated vaccine is ineffective against HFMD with other...
Monitoring of Cd and GSH contents and Bn-OASTL expression in transgenic tobacco seedlings in response to Cd stress
Cadmium (Cd) pollution threatens agricultural productivity and food safety. O- acetylserine(thiol)lyase ( OASTL ) genes...
The effect of comprehensive intervention on family support and the mediating effect between intervention and changes in children’s dietary and physical activity behaviors
Objective Childhood overweight and obesity have become one of the major global public health problems. Family support plays an important role in the development of children’s healt...
Genome-wide identification and multi-dimensional functional characterization of the SIR2 family in Brassica napus L.
Silent Information Regulator 2 (SIR2) family proteins are NAD + -dependent histone deacetylases that play key roles in epigenetic regulation, plant development,...
Productivity losses and treatment cost of benign prostatic hyperplasia in Ghana
Benign Prostatic Hyperplasia (BPH) is a common condition among ageing men, characterized by lower urinary tract symptoms that significantly impact the quality of life and economic productivity of affe...
Correction: DeltaBreed: A BrAPI-centric breeding data information system
Impact of crowdfunding, entrepreneurial finance and varieties of entrepreneurial ecosystems after COVID pandemic for rural women
In this paper, we propose an approach to estimate the role of entrepreneurial finance and social capital distribution in crowdfunding (CF) and varieties of entrepreneurial ecosystems after the COVID p...
Estimated true prevalence and associated risk factors of bovine paratuberculosis antibodies in dairy herds in Bangladesh
Bovine paratuberculosis (PTB), caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a chronic infection that...
Research on self-adaptive height adjustment control of shearer based on deep deterministic policy gradient
As a core component of the fully mechanized mining face, intelligent control of the shearer is fundamental to achieving unmanned mining and improving equipment reliability. To address the limitations...
Bureaucracy, happiness, and satisfaction at work
Despite increasing material prosperity, industrialized nations face declining self-reported happiness and increasing workplace dissatisfaction. This study investigates bureaucratic burden as a driver...
Phytoplankton fatty acid proportions in the Canadian Arctic are strongly affected by temperature, salinity, and phosphate in late summer
Phytoplankton form the base of the food web and act as the main source of both energy, and ω3 essential fatty acids in marine ecosystems. In the Arctic, the effects of climate change are exacerbated c...
A pilot multimodal study of cervical cancer: Raman spectroscopy as a molecular fingerprint tool
Cervical cancer remains a significant global health burden, highlighting the need for more effective tools for early detection and tissue characterization. In this study, we propose a multimodal strat...
Assessing in-hospital mortality risk in ICU lung cancer patients using machine learning: An analysis based on the MIMIC-IV database
Background Patients with advanced lung cancer admitted to the intensive care unit (ICU) face a substantially elevated risk of in-hospital mortality. Early identification of high-ri...
Spontaneous cervical artery dissection is associated with a distinct peripheral immune cell signature
Objectives Despite being a major cause of ischemic stroke in young adults, the biological underpinnings of cervical artery dissection (CeAD) remain poorly defined. Recent data impl...
Latent TB infection in solid organ transplant recipients in Serbia: A single center experience from a low TB burden country
Background Solid organ transplant (SOT) recipients face a heightened risk of latent tuberculosis infection (LTBI) reactivation and progression to active tube...
Evaluating community pharmacists’ involvement in patient counselling and health education in Nairobi, Kenya: A cross-sectional study
Background Community pharmacists serve as the most accessible healthcare providers, playing a pivotal role in patient counselling, health education, and disease prevention. Despite...
Evidence for motor imagery in the management of vestibular disorders does not support recent guidelines: A systematic search and review
Context Vestibular disorders significantly impact people’s quality of life, affecting functions such as balance and walking. Current treatments involve pharmacological and non-phar...
Mechanism and optimization of hydrocyclone-based enrichment of calcium and magnesium in fine coal gangue
Coal gangue, an industrial solid waste generated during coal mining and processing, poses significant environmental challenges due to long-term stockpiling and landfilling. Its comprehensive utilizati...
The influence of generative artificial intelligence usage on employees’ innovative job performance
The rapid advancement of AI technology has accelerated the adoption of generative artificial intelligence (GenAI) tools in the workplace, eroding the boundaries between professional responsibilities a...
Machine learning-based prediction of diabetic retinopathy from pupillary abnormalities in a South Indian population
Diabetic retinopathy (DR) is a common complication of diabetes that can lead to vision loss. Early detection and prevention of DR is crucial to reduce the burden of this disease. The purpose of this s...
Feature recess-time sports activities as a school-based intervention to improve fitness in rural Chinese youth
Background China’s national school health policies face persistent implementation gaps, particularly in rural high schools prioritizing Gaokao. National surveys (2010–2019) documen...
Soil fertility management for yield and income stability in soybean-wheat rotation system under climate variability in subtropical Central India
The soybean–wheat rotation system forms a crucial component of Central India’s rainfed agriculture. Although historically productive and profitable, the system’s sustainability is increasingly threate...