PLoS ONE
Articles in this Issue
Associations between precipitation, temperature, and malaria prevalence in children under 5 in Mali
Malaria is prevalent in Mali and children under 5 are more vulnerable. Temperature and precipitation can affect vector density and parasite development, impacting malaria transmission. This explorator...
Short report: Targeted analysis of whole exome sequencing data in Indian cryptogenic stroke patients
Cryptogenic stroke (CS) is an ischemic stroke of unknown cause with increasing incidence in India. Common and rare genetic variants have been associated with the risk of stroke. We carried out targete...
What type of relationship is learned during visual statistical learning?
Statistical learning enables observers to extract regularities from their environment, but what statistical regularity is extracted remains debated. While previous research has mainly focused on condi...
A scoping review and thematic analysis of the landscape of spiritual health and spirituality in Canada
Literature that focuses explicitly on spiritual health as a dimension of health remains comparatively underdeveloped in many national contexts, including Canada...
FNDC5/Irisin-dependent renoprotection of resistance training in myocardial infarction–induced Type 2 cardiorenal syndrome
Type 2 cardiorenal syndrome (CRS), driven by chronic myocardial infarction (MI), is characterized by renal fibrosis and oxidative stress, yet underlying mechanisms and therapies are poorly defined. Th...
Lessons learned from interdisciplinary US national science foundation research traineeship-supported graduate programs
The National Science Foundation’s (NSF) Research Traineeship (NRT) Program fosters interdisciplinarity. It is designed to train scholars with the agility to move beyond their strict disciplinary bound...
Characterizing mitochondrial phenotypes and MERCS in aged human skeletal muscle myoblasts
Age-associated declines in skeletal muscle function are linked to cellular senescence and mitochondrial alterations, yet mitochondrial phenotypes in aged human myoblasts remain insufficiently characte...
Sustaining grant-funded programs: Conditions for sustaining initiatives that enhance diversity in STEMM
As funding agencies seek to broaden their impact in science, technology, engineering, mathematics, and medicine (STEMM) and workforce diversity, many grants have required plans for sustaining institut...
Moderating effect of temperaments between borderline personality traits and mood instability among a sample of Lebanese adults
Objective The aim of this study is to explore the moderating role of different affective temperaments in the relationship between Borderline Personality traits (BPT) and Mood Insta...
Factors associated with insomnia in hemodialysis patients: A protocol for systematic review and meta-analysis
Introduction Insomnia is a prevalent sleep disorder among hemodialysis (HD) patients, significantly impairing quality of life and increasing mortality risk. However, current eviden...
Does Internet use alleviate household financial vulnerability? An empirical analysis based on panel data from China Family Panel Studies (CFPS)
As digital technologies increasingly shape household financial behavior, understanding their role in buffering financial shocks has become an important policy and research concern. Drawing on panel da...
The psychological impact of major disasters on Japan’s medical system: An SNS text analysis
A major disaster creates an extraordinary situation for medical system. The aim of this study is to evaluate the impact of infrastructure damage caused by a major earthquake on the medical systems in...
Dietary sodium, potassium, and cardiometabolic risk: A cross-sectional analysis of hypertension in U.S. adults from NHANES 2017–2018
Background The relationships between dietary sodium and potassium intake and hypertension remain controversial, with recent population-based analyses yielding inconsistent findings...
The national survey of academic researchers: New facts and data
We introduce a new survey of professors at roughly 150 of the most research-intensive institutions of higher education in the US. We document seven new features of how research-active professors are c...
QRBT: Quantum Driven Reinforcement Learning for Scalable Blockchain Transaction Processing
Scaling and Latency Issues Processing blockchain transactions is a challenge with respect to throughput and latency, while also being resilient against quantum adversaries. To overcome these,m this re...
Barriers to healthcare access among women in sub-Saharan Africa: A pooled analysis of multi-country DHS data (2019–2023)
Background Barriers to accessing healthcare have significantly contributed to the high rates of maternal and child mortality and morbidity in developing regions, particularly in Su...
Research on the path of social psychological collaborative education in colleges and universities driven by the dynamic reward and punishment mechanism of the government
This study addresses the prevalent issues of “coordination failure” and “cooperative inertia” in the collaborative education of mental health between universities and society. Utilizing evolutionary g...
Design and development of a convolutional neural network based on human cognitive attention mechanism for automatic classification of leukemia
Cancer occurs when healthy cells in the body grow abnormally and out of control. Leukemia is a type of cancer that affects White Blood Cells (WBCs) and can cause a lethal infection and early death. Id...
The effect of patient experience with nurses and ward type on intention to recommend: Focusing on integrated nursing and caring service wards and general wards, 2020–2022
Objective This study aimed to compared inpatients’ intention to recommend hospitals between integrated nursing and caring service wards (INCSW) and general wards (GW), and examined...
DrugReasoner: Interpretable drug approval prediction with a reasoning-augmented language model
Drug discovery is a complex and resource-intensive process, making early prediction of approval outcomes critical for optimizing research investments. While classical machine learning and deep learnin...
AdaptiveInvolutionNet: Spatially-adaptive involution with channel-wise attention for breast MRI tumor classification
Background: Early and accurate classification of breast tumors from MRI scans is essential for improving patient outcomes. However, a key limitation of conventional deep learning m...
A cloud-based multi-criteria decision-making framework for green-resilient supplier selection of manufacturing industry
The selection of suppliers is crucial for contemporary manufacturing firms to attain their supply chain goals. With the escalation of global environmental concerns, manufacturing companies are facing...
Unveiling the biochemical potential of Acacia jacquemontii as a therapeutic agent in parkinson’s disease: A multi-model in Vitro, In Vivo, and In Silico Study
Parkinson’s disease (PD) is a progressive neurodegenerative disorder marked by oxidative stress, inflammation, and the degeneration of dopaminergic neurons. Current treatments focus more on symptom ma...
Regional differences, distribution dynamics, and convergence of multidimensional food security levels in the Yangtze river economic belt
Food security is a key foundation for the Yangtze River Economic Belt’s high-quality development. Using a multidimensional food security evaluation framework that encompasses quantity, quality, ecolog...
A supply and demand intervention increased fish consumption among rural women: A randomized, controlled trial
Malnutrition is a critical public health issue in Timor-Leste, where nearly half of children under five suffer from stunting and diets are chronically low in nutrient-rich foods, including fish. We co...