PLoS ONE
Articles in this Issue
Boundary-aware dual-discriminator generative adversarial network for data augmentation in financial transaction fraud detection
The rapid growth of digital payments exacerbates the challenges in Financial Transaction Fraud Detection (FTFD). These challenges stem primarily from an extreme class imbalance, where legitimate trans...
Changes in anemia prevalence and the proportion of anemia associated with iron deficiency or inflammation in young children residing in Puno, Peru: Analysis using new World Health Organization guidelines for defining anemia
Background In 2024, the World Health Organization (WHO) introduced new hemoglobin cutoffs for diagnosing anemia. The WHO also incorporated revised altitude adjustments and lowered...
Mucosal Snare Resection (MSR) in Non-Submucosal Injection Endoscopic Submucosal Excavation (NSI-ESE) for submucosal tumor may not be the preferable choice: A retrospective study
Background and aims Non-submucosal injection endoscopic submucosal excavation (NSI-ESE) and mucosal snare resection-assisted endoscopic submucosal excavation (MSR-ESE) are novel te...
A new mechanism regulating microglial NLRP3 inflammasome: FMR1 mediates NLRP3 mRNA stability
Background The NLRP3 inflammasome drives chronic inflammation and contributes to the pathogenesis of multiple sclerosis (MS). This study aimed to elucidate a novel post-transcripti...
FRCP-YOLO: Road object detection algorithm based on improved YOLOv8n
The accuracy of road object detection is crucial for ensuring the safe driving of autonomous vehicles. Challenges such as small object missed detection, excessive parameters, low accuracy, and poor ro...
Dual function of mitochondrial complex III in Plasmodium falciparum
Complex III of the malaria parasite mitochondrial electron transport chain (mtETC) has been validated as an attractive target for currently used antimalarials. We previously showed that the main funct...
System biology and network-based approach to identify the therapeutic signatures and potential inhibitors against polycystic lipomembranous osteodysplasia with Sclerosing Leukoencephalopathy
Polycystic Lipomembranous Osteodysplasia with Sclerosing Leukoencephalopathy (PLOSL), often recognized as Nasu-Hakola disease, is an uncommon autosomal recessive systemic condition described by numero...
Correction: An open-source closed-loop Virtual Reality system to investigate social interactions and collective behavior in fish
Care practices, popular knowledge, and health promotion among quilombola woman in Brazil
Objective was to investigate the health practices and knowledge among quilombola woman in the ‘Baixada Maranhense’ region, to understand how these practices are transmitted, transformed, and integrate...
Cyanoglobule lipid droplet accumulation as a stress response to nitrogen starvation in a non-N2-fixing mutant strain of Anabaena sp. PCC 7120
Cyanoglobules are lipid droplets of cyanobacteria that share compositional and functional features with plastoglobules of plant chloroplasts. However, their roles in stress physiology remain poorly de...
Unveiling nonlinear effects of Digital Inclusive Finance on urban-rural integration: A threshold panel analysis of China
This paper examines the nonlinear effects of Digital Inclusive Finance (DIF) on urban–rural integration (URI) using a provincial panel for mainland China (31 provinces, 2011–2023). We construct a mult...
Developing and validating a frailty score based on patient-reported outcome 3 months after stroke: A Riksstroke-based study
Background: Frailty is common after stroke and linked to poor outcomes, but many measures are clinician-rated, time-consuming, and not suited to patient-reported data. To address t...
Personally speaking: Developing and evaluating an ontology of dimensions of meaning for self-disclosure with a conversational assistant
Dialogue systems and conversational assistants are promising technologies given their general accessibility and appeal, but longer-term adoption often falters. Creating systems that engage users over...
Trends and associations of pulmonary nodule detection rates in China, 2019–2023: A multicenter cross-sectional study based on Real-World Data
The post-coronavirus disease 2019 (COVID-19) pulmonary sequelae have garnered public concern. We conducted a multicenter cross-sectional study in outpatient and health exam populations from 23 clinica...
Joint modeling of alcohol and tobacco use among adults in Uganda
Alcohol and tobacco use are leading modifiable risk factors for non-communicable diseases (NCDs) worldwide. In sub-Saharan Africa, including Uganda, these behaviors are increasingly common but often a...
Navigating multidimensional obstacles: a comparison between young and older adults and among obstacles
Most falls in older adults are due to tripping over objects. Older adults cross obstacles with greater toe clearance to prevent tripping, indicating obstacles may be more consequential when compared t...
Obtention and preliminary clinical evaluation of an equine albumin for intravenous administration in adult Colombian Creole Horses (Equus ferus caballus)
Albumin is one of the most abundant and physiologically important blood protein in horses due to its ability to regulate vascular volume and transport blood metabolites or drugs. Despite the importanc...
Remdesivir-bisPropionate, a better derivative of remdesivir against SARS-CoV-2: Comparison of in vitro and in vivo PK/PD Study as well as its therapeutic potential
FDA approved remdesivir, which was though very effective against SARS-corona virus in cell culture system but in human its efficacy was below 10%, as reported. The main reasons are due to the poor sta...
Determinants of medication adherence and knowledge among patients with Type 2 diabetes mellitus: A cross-sectional study in Northwestern China
Objectives The study aimed to evaluate medication knowledge and adherence among patients with type 2 diabetes mellitus (T2DM) in northwestern China, identify factors influencing ad...
Association of anxiety and depression with cognitive challenges in children in Bangladesh
This study primarily investigated the association of anxiety or depression (AD) with communication, learning, remembering, or concentrating (CLRC) difficulties in children aged 5-17 years in Banglades...
The emergence of hyperendemic dengue in Bangladesh: An ecological study of structural breaks and transmission regime shifts, 2008–2025
Background Dengue fever in Bangladesh has escalated from sporadic outbreaks to a persistent, nationwide health crisis. Traditional epidemiological analyses often assume a constant...
An experiment on the impacts of experiential investment advice
An experiment is conducted in which investment advice is passed from one cohort to the next. Participants make asset allocation decisions for thirty years to a safe and risky asset and provide annual...
Numerical investigation of a reaction-diffusion model used for rumor spreading in a ‘street’
In this paper, a reaction-diffusion model is proposed to describe the dynamics of rumor propagation among ignorant (who have not heard the rumor and are susceptible to be informed), spreader (who are...
RWDisEnh+: Enhancing disease-enhancer association prediction through multiplex-heterogeneous networks
Enhancers are critical regulatory DNA elements that, when dysregulated, can contribute to disease pathogenesis by altering gene expression. Although millions of enhancers have been identified through...
What do people want to know about another person? The answer depends on whether that person is an adult or a child
Research shows that when seeking information about others, people prioritize information about warmth and competence. In those studies, target persons were adults. How might information-seeking priori...