PLoS ONE
Articles in this Issue
Controlled deposition of human neural stem cells on fiber substrates using gel encapsulation
Electrospinning is a versatile technique for manufacturing micro-nano diameter fibers and has been used extensively for tissue engineering in vivo and advanced cell culture in vitro. Standard means of...
Vigi4Eudra-score: Evaluation of the completeness of spontaneous adverse drug reaction reports in EudraVigilance
Introduction The vigiGrade completeness score established in VigiBase, the worldwide ADR database, measures the completeness of information provided in the structured format of eac...
Masculinities and suicide: A systematic review and meta-analysis
Background Women are more likely to report suicidal ideation and make suicide attempts, while men are more likely to die by suicide. There has been much discussion of the possible...
Mechanistic insights into triclosan-induced hepatotoxicity: A network toxicology and molecular docking approach
Background Triclosan (TCS) is an artificially synthesized broad-spectrum antimicrobial agent, which is widely used in personal care products. It is a new endocrine disruptor and ha...
Ultrasound assessment of tibial nerve cross-sectional area in diabetic peripheral neuropathy in the Thai Population
Early recognition of DPN gives physicians the opportunity to deliver appropriate treatment and counseling to minimize subsequent complications. This study aimed to evaluate the diagnostic performance...
Influencing factors and mechanisms of action on the participation intentions of cryptocurrency investment fraud victims—A quantitative examination from the perspective of the theory of planned behavior
With the rise of cryptocurrency, using cryptocurrency investments to conduct fraud has become a common criminal tactic. Drawing on survey data from 287 victims in China, this study explored the determ...
Conservative management of cervical intraepithelial neoplasia grade 2 and immunohistochemical staining of p16 and Ki-67: Data from a Brazilian institution
Introduction Cervical intraepithelial neoplasia grade 2 (CIN2) includes both transient HPV infections and precursor lesions of cervical cancer. Conservative management aims to avoi...
The mosaic of science: Disciplinary diversity and scientific prestige in research groups in Colombia
Collaboration among science teams is essential for addressing complex global challenges. A key feature of such collaboration is disciplinary diversity; however, its relationship with team performance...
Episiotomy practices and associated factors in central Vietnam
Introduction Research on episiotomy practices in Vietnam is limited. This study aimed to describe episiotomy use and identify factors associated with its practice among vaginal bir...
The effect of adding colostrum or sodium butyrate to the diet on the intestinal barrier of weaned piglets
Weaning is a critical stage for piglets, often leading to intestinal barrier disruption, impaired nutrient absorption, and growth reduction. This study investigated the effects of dietary supplementat...
Transcriptomic response of skeletal muscle to acute aerobic versus combined exercise in chronic kidney disease
Background Chronic kidney disease (CKD) affects approximately 14% of the UK population and is associated with significant exercise intolerance, partly due to skeletal muscle dysfun...
Relationship between parenting stress profiles, work-family conflict, and adolescent problem behavior: Variable-centered and person-centered approaches
Background Adolescent problem behaviors, including both internalizing (e.g., emotional symptoms) and externalizing difficulties (e.g., conduct problems, hyperactivity), are a signi...
Exploring infant gut–derived probiotics through 16S rRNA identification and in vitro functional characterization
The infant gut microbiota significantly influences health outcomes, impacting digestion, immunity, and metabolic processes. Identifying beneficial microbes from this source offers promising avenues fo...
Understanding high fructose corn syrup in popular snacks: Consumption, perceptions and labeling preferences
At a time when the Make America Healthy Again (MAHA) initiative brought renewed attention to High Fructose Corn Syrup (HFCS), this study explores the potential of supplemental labeling to inform consu...
Correction: Association of myopia and parapapillary choroidal microvascular density in primary open-angle glaucoma
Long-term effects of a severe tropical cyclone on coral reef habitat and fish assemblages at the Whitsunday Islands, central Great Barrier Reef
Coral reef habitats and associated fish communities can be severely impacted by physical disturbances such as storms and cyclones, which can dramatically reduce live coral cover. However, rapid coral...
Evaluation of a collaborative care system in primary care in the implementation of ambulatory follow-up in mental health: A study protocol
Access to secondary psychiatric consultation is often challenging for general practitioners (GPs), potentially resulting in treatment delays or increased reliance on emergency services. The...
Reliability of tachycardia as an early warning sign in acute clozapine-induced cardiac inflammation: Protocol for a systematic review
Introduction Clozapine-induced cardiac inflammation (CICI) can have serious consequences for people with psychosis and can be fatal if not detected in a timely manner. The best ava...
Reusable multicriteria decision model to evaluate the integrated sustainability impacts of different alternatives of dietary substitutions
Policies promoting shifts towards sustainable diets must consider the health, environmental, and socioeconomic impacts of changes and the trade-offs among these impacts across options. Comprehensive a...
Correction: Early skeletal muscle loss and clinical outcomes in critically ill patients in the medical intensive care unit: A retrospective cohort study
Critical success factors influencing business intelligence adoption: Evidence from Yemen
Over the past five decades, decision support systems have evolved into business intelligence (BI) systems, which are now a strategic priority for many organizations. However, despite their widespread...
Correction: Factors influencing surgecon implementation in four Canadian emergency departments guided by consolidated framework for implementation research
Drought characteristics and their impact on vegetation net primary productivity in the climate-sensitive transition zones of North China
Net Primary Productivity (NPP) serves as a key measure of ecosystem production capacity and carbon absorption ability. Evaluating the arid characteristics and their NPP impact in the climate-sensitive...
Anti-inflammatory activity and metabolite profiling of myo-inositol in LPS-stimulated macrophages
There has been increasing interest in using dietary bioactive substances to alleviate and reduce inflammation. This study aims to assess myo-inositol’s possible anti-inflammatory effects, especially i...
Optical coherence tomography-derived coronary vessel wall abnormalities in adults long after Kawasaki disease
Background Children with a history of Kawasaki disease (KD) and severe coronary involvement are at risk for acute coronary syndrome later in adulthood even in the absence of severe...