PLoS ONE
Articles in this Issue
Machine learning-driven optimization of monolithic gold plasmonic sensors: Achieving ultrahigh sensitivity with interpretable linear models
Integrating machine learning (ML) with nanophotonic engineering, this work achieves unprecedented performance in surface plasmon resonance (SPR) biosensing through a co-designed gold-coated photonic c...
Forecasting emergency department visits in the reference hospital of the Balearic Islands: The role of tourist and weather data
Accurate forecasting of patient arrivals at emergency departments (EDs) is vital for efficient resource allocation and high-quality patient care. In this study we investigate the relevance of exogenou...
Effect of iodine nutrition on blood glucose and blood lipid levels in different regions: Based on quantile regression
Objective Iodine is essential for the synthesis of thyroid hormones in the human body, and both excessive and insufficient iodine intake can significantly impact metabolic processe...
Longitudinal evidence of technology-enhanced, individualized neuromotor rehabilitation on autonomy, cognition, quality of life, and psychological well-being: Pilot multi-sample study
Background Over the last decades, neuromotor rehabilitation programs have integrated multidisciplinary approaches with the implementation of emerging technology (e.g., robotics and...
Elucidating the mechanistic association of xylene inducing non-small cell lung cancer through network toxicology and molecular docking analysis
Xylene is a common industrial solvent that includes three isomers: o-xylene, m-xylene, and p-xylene. Long-term exposure to low doses of xylene in the environment has been linked to a higher risk of lu...
Capacity and site readiness for hypertension control program implementation in Nigeria: A nationwide cross-sectional study
Background The aim of this study is to determine the capacity and readiness of Nigerian primary healthcare facilities to adopt a multi-level approach for the diagnosis, treatment,...
The dolutegravir failure cohort: A multi-country longitudinal cohort with a randomised clinical trial of continued dolutegravir versus switch to darunavir in people with viraemia while on dolutegravir in Sub-Saharan Africa (The Ndovu Study) protocol
Background There is insufficient data to inform the management of dolutegravir failure, with the WHO and various countries adopting different approaches, underscoring the need for...
The role of phase angle and standardized phase angle in assessing nutritional status and predicting complications in gastrointestinal cancer
Objective This study aims to look at the link between bioelectrical impedance analysis (BIA), especially phase angle (PA) and standardized phase angle (SPA), and how often postoper...
Influence of environmental factors and tributaries on toxic cyanobacterial growth
Toxic cyanobacteria are widely present in water bodies worldwide, particularly in reservoirs. The Calima Reservoir is primarily used for energy generation, but some areas of it are also designated for...
Bayesian networks for predicting clinical outcomes in COVID-19 patients: A retrospective study in a resource-limited setting
Background The COVID-19 pandemic has highlighted the critical need for robust, interpretable predictive models to guide clinical decision-making for hospitalized patients, particul...
Vector fields as a framework for modelling the mobility of commodities
Commodities flow through trade networks across the world, with trajectories that can be effectively modelled using approaches similar to those used in human mobility studies. Yet, documenting these mo...
A scoping review of EFL learners’ interlanguage pragmatic development
Interlanguage pragmatics (ILP) development refers to how L2 learners manage actions, identities, and social relations through language in interaction. The rapid transition to multimodal, digitally med...
Experiences, outcomes and unmet needs of caregivers of children with Cerebral Palsy in Spain: Protocol for a mixed-methods study
Cerebral Palsy is one of the most prevalent motor disabilities in childhood, significantly impacting both children and their caregivers. This mixed-methods study explores the experiences, psychologica...
Progressive damage mechanism and multiscale characterization of hard sandstone-coal composite structures under loading
Under geological conditions characterized by deep high-stress zones, intense mining disturbances, and hard roof strata, primary fractures on and within coal bodies are highly susceptible to expansion...
Pruning-fruit retention and plant models strategies to improve growth, quality, and yield of netted melon in Arid regions
Netted melon ( Cucumis melo var. reticulatus ) exhibits strong environmental adaptability and high economic value, making it a widely favored horticultural crop...
Early clinical and laboratory markers associated with post-COVID respiratory syndrome: A retrospective analysis
Background Post-COVID-19 respiratory syndrome remains a significant concern, yet early clinical and laboratory markers at the time of admission are not well established. Identifyin...
Evaluation of alkali residue-stabilized soil in road construction with optimization of mechanical properties and environmental risk assessment
The effective utilization of alkali residue (AR) is a central issue and an urgent challenge for the green transformation of the soda ash industry. While research has primarily focused on the mechanica...
Evaluating the quality of social media content on metabolic dysfunction associated steatotic liver disease: An experience from a lower middle-income country
Introduction Metabolic dysfunction associated with steatotic liver disease (MASLD)/non-alcoholic fatty liver disease (NAFLD) represents a significant public health concern. Social...
Antioxidant and antibacterial potential of bioactive extraction from Cadaba glandulosa leaves
This study investigated the bioactive components and explored the antioxidant and antibacterial properties of the methanolic leaf extracts of Cadaba glandulosa...
Protocol for a cluster-randomized control trial of a remote workplace resilience intervention for early care and education providers: The OnWARD trial
Work-related stressors take a toll on individuals’ health and well-being, a toll which is often heavier for under-resourced, low-paid segments of the essential workforce who serve our communities. Res...
Dense retrieval and reranking for referenced provisions in electric power audit systems
Electric power audits require practitioners to describe an audit issue and justify the final opinion by citing an appropriate referenced provision. In practice, the referenced provision should be retr...
Implementing substance use services into acute care settings for pregnant and birthing people: A systematic scoping review of implementation and quality improvement strategies
Pregnant and birthing people with untreated substance use disorders (SUDs) face multiple risks of mortality and morbidity. Acute care settings (i.e., hospital inpatient, labor/delivery and emergency d...
Examining the longevity of trade partnerships: A duration analysis of Ethiopia’s international trade flows
This study examines the longevity of Ethiopia’s trade partnerships duration and its determinants using a survival analysis. While the existing literature extensively studies the determinants of trade...
Study protocol for a mixed methods convergent investigation of family domestic and sexual violence in multiple sclerosis and broader neurology in Australia
Background People with disabilities experience disproportionately high rates of family, domestic, and sexual violence (FDSV), yet recognition and response in...