PLoS ONE
Articles in this Issue
Are teachers missing the beat on students’ motor competence?
Purpose Compare physical education (PE) teachers’ perceptions of their students’ motor competence (MC) with students’ objectively assessed actual motor competence....
Correction: Low level of plasma DNase is associated with worse clinical outcome in testicular germ cell tumor patients and exogeneous DNase I improves cisplatin treatment efficacy
Risk identification strategies for health pandemics and epidemics on college campuses: A comprehensive analysis of heat maps and behavioral observations
Objective The purpose of the current studies was to use direct observation and surveys to assess behavioral risk on a college campus during the COVID-19 pandemic....
Multi-omics analysis identifies CCNB1 as a cell cycle factor driving glioblastoma progression and its inhibition by resveratrol
Glioblastoma (GBM) is a fast-growing primary brain tumor with high mortality and recurrence rates. Dysregulation of the cell cycle is a hallmark of GBM, and cyclin B1 (CCNB1) is a key regulator of the...
Correction: SPAG6 hypermethylation silences a novel tumor suppressor and inhibits renal cell carcinoma progression via PI3K/AKT/mTOR pathway
Navigating COVID-19: Association between public perceptions of preventive measures and delayed or foregone care among young and middle-aged Korean adults in the early phase of the pandemic
The COVID-19 pandemic has had a profound impact on healthcare systems worldwide, leading to significant disruptions in healthcare services and an increase in delayed or foregone care. South Korea has...
Changes in infant head shape: Developmental trends during the first year of life and secular changes observed in recent years
The cephalic index (CI), defined as the percentage of head width to length, has been used in multiple studies. However, CI only provides 2D information, and comprehensive methods to assess the 3D cran...
Burden, risk factors, and clinical outcomes of pediatric malaria in Nigeria: A systematic review and meta-analysis protocol
Background Nigeria ranks number one globally in malaria burden, with the exact burden, especially for hospitalization, unknown. This systematic review and meta-analysis will pool l...
Mechanisms of action of bile acids in pediatric gastroesophageal reflux: Exploration through non-targeted and targeted metabolomics methods
Purpose To investigate the pathogenesis of pediatric bile reflux gastritis (BRG) using non-targeted and targeted metabolomics analyses of the changes and content differences of bil...
Socioeconomic, physical and mental health impacts of climate change among informal outdoor workers in sub-Saharan Africa: A scoping review protocol
The informal economy plays a critical role in Sub-Saharan Africa (SSA), yet informal outdoor workers are disproportionately exposed to climate-related hazards. Existing reviews often merge formal and...
Validating the AIM–N: An AI-motivation and needs scale with multi-group invariance and MIMIC-DIF evidence in higher education
The rapid adoption of generative AI in higher education raises critical questions about its impact on student motivation and basic psychological needs. This study introduces and validates the AI-Motiv...
Chabazite-supported ZnO and CeO2 nanoparticles with structural stability and enhanced antibacterial action
Chabazite (CHA) was synthesized by the hydrothermal fusion method, and zinc oxide/cerium oxide nanoparticles (ZnO/CeO 2 -NPs) supported on CHA were subsequently...
Comparative analysis of stress markers, metabolic health, and gut microbiota in healthy and disabled dogs in long-term shelters in Thailand
Regular welfare assessments are essential for identifying and addressing the physical, behavioral, and emotional needs of shelter dogs, thereby ensuring their well-being and improving chances for adop...
Effect of anticancer activity of aripiprazole main metabolite OPC-14857 on malignant glioblastoma
Glioblastoma is an incurable and highly malignant brain tumor that poses challenges in surgical and chemotherapeutic treatments. Aripiprazole (ARP), an antipsychotic drug, exerts cytotoxic effects aga...
Physicochemical status of Nwanedi river water, and its influence on the metabolome of river-irrigated tomato leaves
Contaminated water used for irrigation has been reported to trigger metabolic and physiological changes in plants. This study assessed the physicochemical status, pH, total dissolved solids (TDS), ele...
Rehabilitation outcomes following tail-fluke amputation in an Indo-Pacific bottlenose dolphin: A welfare-centered approach
Tail fluke loss in cetaceans compromises locomotion and impairs social functioning, posing serious welfare challenges. Rehabilitation strategies that address both physical performance and behavioral r...
The effect of intradialytic resistance exercise on physical function and dialysis adequacy in patients on maintenance hemodialysis
Background Chronic kidney disease poses a growing global health concern and is linked to several complications with higher prevalence and intensity in the hemodialysis (HD) populat...
A new perspective on population genetics: Deciphering the relationship between genetic variants and disease prevalence in Psoriasis
In the quest to identify the genetic underpinnings of complex diseases, we developed a novel approach called Causal Genotype Combination Patterns (CGCP) to uncover characteristic genetic signatures of...
Is the process of successful sexual aging different in older partnered and non-partnered adults?
As populations in the Western world age, interest in the sexual health and well-being of older adults has grown substantially, yet positive models of sexual aging remain underexplored—especially acros...
Determining farm surface porcine reproductive and respiratory syndrome virus (PRRSV) contamination through viability RT-qPCR
Porcine reproductive and respiratory syndrome (PRRS) continues to be a major threat to U.S. swine industry, as a substantial number of herds become positive and can pose a risk to other nearby farms,...
Development of a monoclonal antibody-based competitive ELISA as a surrogate assay for detecting neutralizing anti-interferon gamma autoantibodies in adult-onset immunodeficiency
Neutralizing anti-interferon gamma autoantibodies (nAIGAs) play a pivotal role in the pathogenesis of adult-onset immunodeficiency (AOID), predisposing affected individuals to severe opportunistic inf...
DNA metabarcoding on roadkill stomach contents reveals the breadth of species present in bobcat diets
Trophic dynamics can be altered in complex ways as a result of urbanization. Understanding predator diets in these contexts may not only provide insight into these changes, but also in sources of mort...
Genotype by environment interaction and yield stability analysis of durum wheat (Triticum turgidum var. durum) varieties using AMMI and GGE biplot analysis in Amahara Region, Northwest Ethiopia
Durum wheat is a staple crop for over one- third of the global population; however, its production in Ethiopia, particularly in the Amhara Region, faces major challenges due to limited adaptable varie...
Best reference genes for unbiased normalized transcript expression in normal and dystrophic human cell models of myogenesis
Patient-derived cell models of dystrophic myogenesis and differentiation are valuable preclinical tools for early and mutation-based assessment of candidate therapeutic approaches. Quantitative measur...
The influence of paternal preconception health on infant birth weight: A scoping review
Birth weight is an important determinant of infant growth and development associated with neonatal morbidity (e.g., respiratory distress, hypoglycemia) and mortality, as well as long-term health risks...