PLoS ONE
Articles in this Issue
Can the current radiation dose, in chest tomosynthesis, be reduced with retained image quality? A study in the context of lung cancer screening programs
Objective Digital chest tomosynthesis (DTS) is a low-cost and low- dose imaging technique that has not yet reached general use. It might, however, be well suited to lung cancer scr...
Detection of rare medical events in electronic health records using machine learning: Current practices and suggestions – A scoping review
Background Routine healthcare data are increasingly stored in electronic health records (EHRs), presenting an exciting opportunity to leverage machine learning (ML) for detecting a...
Limonin induces ferroptosis in cervical squamous cell carcinoma by activating the expression of soluble epoxide hydrolase 2 protein
Natural products are a rich sources for developing anti-cancer drugs with low toxicity and high efficiency. Limonin has anti-cancer activity; however, its effect on cervical squamous cell carcinoma re...
Serum levels of immunoglobulin G and M antibodies against SARS-CoV-2 in asymptomatic individuals prior to COVID-19 vaccination in the Democratic Republic of Congo
Despite the production of protective cross-reactive antibodies during COVID-19, data on immunoglobulin G (IgG) and immunoglobulin M (IgM) levels prior to vaccination remain limited in the Democratic R...
Non-linear impacts of local fiscal expenditure on farmers’ income: A SHAP-informed machine-learning analysis
Understanding how local fiscal spending shapes rural income is central to China’s rural revitalisation strategy. Using panel data from 17 prefecture-level cities in Henan Province for 2010–2023, this...
Policy Modeling Consistency index-based study on policy synergy for sustainable artificial intelligence in China’s digital cultural industries
This paper applies the Policy Modeling Consistency (PMC) index model to quantitatively evaluate 32 Chinese policies (2016–2025) promoting artificial intelligence (AI) in digital cultural industries (D...
Is it inside my head? Characterization of sound externalization in schizophrenia
Schizophrenia has been linked to reality monitoring confusions, particularly misattributions of internal productions to external sources. We hypothesized that these misattributions may be related to d...
Correction: Workplace stress, support and stress management strategies for healthier lifestyles among healthcare workers in Ethiopia
Assessing the impact of timely diagnosis on psychological outcomes and quality of life for cancer patients: A scoping review
Objective We explored the literature on timely cancer diagnosis and its significance on psychological outcomes or quality of life in cancer patients....
Helping primary care providers recognize and respond to medication non-adherence and drug-drug interactions: A randomized-controlled clinical utility trial in a value-based care setting
Objective To determine the clinical utility of a novel chronic disease management test among primary care providers practicing in a value-based care setting. The study assessed the...
New insights into the feeding behaviour of the Japanese squid Todarodes pacificus paralarvae, and a combined analysis of metagenome and amino acid isotope ratios
The Japanese flying squid Todarodes pacificus (Ommastrephidae) is a commercially and ecologically important species; however, there remains much room for invest...
Application of construction site management based on digital twin and point cloud semantic segmentation technology
Construction sites are particularly susceptible to the effects of extreme weather, with unsafe items posing a significant risk of causing substantial damage to construction projects and neighboring co...
A pilot randomized controlled trial to explore the feasibility of a peer-delivered single-session brief intervention for youth with moderate risk substance use
Background Youth in sub-Saharan Africa are at high risk of substance use yet lack access to appropriate interventions. The goal of this project was to evaluate the feasibility of a...
Health care system resilience - Evaluating the effect of the COVID-19 pandemic on emergency medical service demand in Germany: A case study from the city of Jena
Background The COVID-19 pandemic has impacted health systems globally, including emergency medical services (EMS). This study evaluates the absorptive and adaptive resilience of EM...
Evaluating hypothetical interventions effects on hospital-acquired infection outcomes with stacked probability visualization: R Shiny apps based on a multistate modelling approach
Background Hospital-acquired infections (HAIs), contribute to increased morbidity, prolonged hospital stays, and higher healthcare costs. Evaluating interven...
Deep learning–driven image captioning: Progress through transformers and large language models
This paper provides a novel deep learning model for captioning of images by using an advanced vision transformer architecture with a powerful LLM. Proposed models show a significant improvement over t...
Cardiorespiratory fitness attenuates the association between psychosocial stress and cardiometabolic risk – Results from the SCAPIS population
Aims Low cardiorespiratory fitness (CRF) and high psychosocial stress can contribute to cardiovascular disease. CRF is a strong predictor of cardiovascular outcomes, yet population...
Decisions about risk taking: Elaborate dynamics between guests and hosts of peer-to-peer accommodation during COVID-19
This study explores the influence of COVID-19 on peer-to-peer accommodation, from perspectives of both market performance and guests’ mindset. Combination of qualitative and quantitative data, as well...
Correction: Xiphovelopsis, a new South American genus of Microveliinae (Hemiptera, Heteroptera, Gerridae), with the description of a new species
Long-term farming and cropping systems with contrasting nitrogen forms and input diversity influence soil prokaryotic diversity in the central highlands of Kenya
Background Understanding how farming systems management influences soil microbial communities is essential for advancing sustainable agriculture in tropical regions. Long-term expe...
Correction: Understanding street protests: From a mathematical model to protest management
Study on the microstructure and properties of laser-cladded AlCoCrFeNiCu0.5-xNbₓ high-entropy alloy coatings
In this study, the high-entropy alloy AlCoCrFeNiCu0.5 − xNbx (x = 0, 0.1, 0.2, 0.3, 0.4, 0.5) is selected as the research subject. Coatings with varying Cu/Nb ratios are fabricated by laser cladding....
The relational association between multiple sexual partners and HIV testing on cervical cancer screening among women of reproductive age in Ghana: A national population-based study
Background Cervical cancer screening remains vital in the early detection of precancerous lesions and promotes better treatment outcomes. Though evidence suggested multiple sexual...
Vegetation cover fraction and the residential distribution of child-rearing households in urban Tokyo and Osaka: An ecological cross-sectional analysis
In Japan, promoting the long-term settlement of child-rearing households is critical to counteract community decline driven by a falling birthrate and an aging population. Most previous studies on res...
Influences of azolla-derived biofertilizer and compost on soil chemical properties and rice growth in contaminated soil
Pollution caused by heavy metals and extensive use of synthetic fertilizers has harmful effects on soil organic matter content, soil health, environmental safety, and human health. To overcome these p...