PLoS ONE
Articles in this Issue
Identification and characterization of two new markers for differentiating fall armyworm strains across the Western Hemisphere
The fall armyworm (FAW) ( Spodoptera frugiperda (J.E. Smith)) is a major pest of corn and several other crops. Although native to the Western Hemisphere, establ...
A large language model framework for sample-free population synthesis
Synthetic populations provide the demographic foundations for agent-based models in transport, public health, disaster management and other sectors, enabling credible representations of individual cha...
Socio-cultural components related to the cropping, harvesting, and consumption of guayusa (Ilex guayusa Loes) in Amazonian Kichwa communities
Guayusa ( Ilex guayusa Loes) is an Amazonian plant whose leaves contain chemical compounds with therapeutic and energizing properties. For the Kichwa nationalit...
Correction: Expression of Concern: Signaling Networks Associated with AKT Activation in Non-Small Cell Lung Cancer (NSCLC): New Insights on the Role of Phosphatydil-Inositol-3 kinase
Gastroesophageal reflux symptoms and sleep quality among medical students at a private university in Lima, Peru: A cross-sectional study
Introduction Poor sleep quality is common among medical students and is associated with academic and health-related consequences. Gastroesophageal reflux disease (GERD) may contrib...
Tracing the journey: Patient engagement in long-term antiretroviral therapy care in Malawi
Background Consistent engagement in antiretroviral therapy (ART) care is crucial to improve health outcomes and reduce HIV transmission. This study examined ART engagement patterns...
3D object detection for vehicle-mounted LiDAR based on deep learning and euclidean clustering algorithm
Object Detection (OD) stands as a fundamental task in the area of autonomous driving environment perception. This study introduces a 3D OD method grounded in deep learning and an improved Euclidean cl...
Postmastectomy radiotherapy in pN1 breast cancer: Survival outcomes and prognostic factors from a single-institution cohort
Purpose/Objectives The role of postmastectomy radiotherapy (PMRT) in patients with pathologic N1 (pN1) breast cancer, including triple-negative breast cancer (TNBC), remains contro...
The impact of malaria-induced neutrophil subset shift and a link to Burkitt lymphoma
Burkitt lymphoma (BL) is an aggressive B-cell lymphoma that remains a leading cause of childhood cancer mortality in sub-Saharan Africa. Although the epidemiological link between P...
Establishment and application of a quadruple target real-time PCR assay for detecting Yersinia pestis
In order to establish an efficient method for high-throughput detection of Yersinia pestis (Y. pestis) , a quadruple target real-time polymerase chain reaction...
Experiences, challenges, and enablers for promoting interprofessional education among medical students: A scoping review
Background Interprofessional education (IPE) has been commonly employed to facilitate preparation for collaborative practice among medical students. However, differences in IPE imp...
Digital exercise interventions to improve physical functioning of people with breast cancer: Protocol for a scoping review
Introduction Breast cancer incidence rates are rising due to early detection, improved screening methods and advances in treatment options. As mortality rates reduce, there is a gr...
Potent and broad-spectrum anti-Candida activity of 6α-(3’-methoxy-4’-hydroxybenzoyl)-lup-20(29)-ene-3-one, a triterpenoid from Paullinia pinnata
Vulvovaginal candidiasis is a common infection that affects women of reproductive age, with a high prevalence among pregnant women. When left untreated, it can lead to pregnancy complications includin...
Prevalence of dental caries in the primary, mixed and permanent dentitions in Nigeria: A systematic review and meta-analysis
Background The national prevalence of dental caries in Nigeria is currently unknown. The objective of this systematic review and meta-analysis was to determine the prevalence of de...
Impact of pre-segmented regions on CT-based evaluation of the Peritoneal Cancer Index: A reader study
Objectives Accurate assessment of peritoneal tumour burden is crucial for treatment selection and prognosis. The Peritoneal Cancer Index (PCI), traditionally assessed by laparoscop...
Physical activity and sedentary behavior surveillance using accelerometers in Japanese urban adults: A descriptive study of participation and adherence
Background Representative data collection in accelerometer-based physical activity and sedentary behavior surveys is challenging. Although in-person protocols and monetary incentiv...
An integrated method for state of charge estimation, lifetime prediction, and reliability assessment of Lithium-ion batteries under thermal and dynamic conditions
Accurate estimation of the state-of-charge (SOC), remaining useful life (RUL), and reliability of lithium-ion batteries is essential for renewable energy storage and electric mobility systems. This pa...
Associations between systemic inflammation, nutritional status, and cardiometabolic diseases and risk factors among adults living in transitional rural communities in Ecuador
Background Chronic low-grade systemic inflammation, as indicated by elevated high-sensitivity C-reactive protein (hs-CRP), has been implicated in the pathogenesis of cardiometaboli...
Experimental and quantitative observational research in fencing and wheelchair fencing: A scoping review
Background Fencing and wheelchair fencing are Olympic and Paralympic sports with growing global participation and increasing scientific interest. However, the overall structure, me...
Expression of Concern: Genomewide Association Studies for 50 Agronomic Traits in Peanut Using the ‘Reference Set’ Comprising 300 Genotypes from 48 Countries of the Semi-Arid Tropics of the World
Triglyceride-glucose-based indices in relation to vitamin D concentrations among adults with metabolic syndrome
Background The concurrent global epidemics of 25-hydroxyvitamin D (25[OH]D) deficiency and metabolic syndrome (MetS) pose substantial public health challenges. This study investiga...
Association between pan-immune-inflammation value and clinical outcomes in critically ill patients with hyperlipidemia: An observational study
Background Hyperlipidemia contributes to immune-inflammatory imbalance and poor outcomes in critical illness. The pan-immune-inflammation value (PIV), derived from neutrophil, mono...
Expression of Concern: Genetic Diversity and Demographic History of Cajanus spp. Illustrated from Genome-Wide SNPs
Study on the pathogenesis of PLXNB1 gene in olfactory dysfunction of allergic rhinitis
Background Olfactory dysfunction (OD) is a common yet underrecognized symptom of allergic rhinitis (AR). While inflammation contributes to OD, the underlying molecular mechanisms r...
Study protocol for OtoSurg 1: A prospective evaluation of worldwide tonsillectomy indications, techniques, and outcomes
Background Tonsillectomy is the most common pediatric surgery performed globally, yet little is known about how tonsillectomy outcomes vary worldwide....