PLoS ONE
Articles in this Issue
Imaging strategies for follow-up during adjuvant nivolumab in esophageal cancer: A multicenter retrospective cohort study
Introduction Adjuvant nivolumab improves disease-free survival in patients with esophageal or gastroesophageal junction cancer following neoadjuvant chemoradiotherapy and resection...
A unified spatiotemporal–geometry framework for target classification and localisation in dual-static passive radar
Passive radar exploits ambient broadcast signals and requires no dedicated transmitter, making it attractive for covert surveillance and target monitoring. A fundamental difficulty arises at low signa...
Behavioral barriers in the management of spinal muscular atrophy: The role of procrastination, regret, and burnout
Background Decision-making in complex medical conditions is a cognitively demanding task influenced by clinician-specific behavioral factors. Procrastination, the voluntary delay o...
A process-guided uncertainty-aware deep learning framework for reliable and interpretable industrial fault diagnosis
Timely fault detection is essential for safety, product quality, and energy efficiency in advanced industrial processes. However, many existing fault diagnosis methods insufficiently exploit process s...
The role and targeting potential analysis of angiogenesis-related target THY1 in DSS-induced acute colitis in mice
Background Immune-driven inflammatory angiogenesis plays a crucial role in the pathogenesis of inflammatory bowel disease (IBD). However, the mechanism of chronic inflammation medi...
Validation and evaluation of diagnostic tests for Schistosoma mansoni in Brazil: The ValidaXisto study protocol
The persistence of schistosomiasis as a serious public health problem can be attributed, in part, to the lack of more accurate diagnostic techniques, particularly in areas with low prevalence and low...
Hydrocarbon generation kinetics and history of source rocks in different salinity environments, Dongpu Depression, Bohai Bay Basin, China
The Dongpu Depression is a typical petroliferous depression characterized by remarkable variations in sedimentary salinity. To investigate hydrocarbon generation characteristics of source rocks in dif...
Is resilience linked to stress response among anesthesia professionals? A prospective simulation-based study
Objectives Anesthesiology is a stressful specialty characterized by high rates of burnout among its practitioners. Resilience, defined as a dynamic process of positive adaptation i...
Tokophobia and associated factors in pregnancy: A community-based cross-sectional survey
Background Fear of childbirth (tokophobia) impacts maternal health, yet its prevalence and associated factors remain underexplored in Lagos. This study aimed to determine the preva...
Microbiological quality assessment of potential pathogenic bacteria and multidrug resistance patterns in commercial electrolyte drinks in Dhaka, Bangladesh
Local electrolyte drinks in Bangladesh are produced without approval from the Bangladesh Standards and Testing Institution (BSTI). Hence, this study aimed to identify foodborne bacteria from electroly...
The prognostic value of the early neutrophil-to-lymphocyte ratio for 28-day mortality in sepsis patients: A machine learning-based investigation of the MIMIC database
Background The neutrophil-to-lymphocyte ratio (NLR) has shown inconsistent prognostic value in individuals with sepsis. This study aimed to clarify its ability to predict 28-day mo...
Multi-phantom SAR-assessed ultra-compact dual-band millimeter-wave (mmWave) antenna optimised for 5G smartphones
This paper presents an ultra-compact millimetre-wave antenna designed to support 28 GHz and 38 GHz 5G smartphone applications. To ensure safe and reliable integration, a comprehensive specific absorpt...
Expression of Concern: Evaluating the compressive strength of glass powder-based cement mortar subjected to the acidic environment using testing and modeling approaches
Female cyclists perceived effects and experiences of the menstrual cycle on training and performance
The aim of this study was: (1) to understand female cyclist’s experiences and perceptions of the menstrual cycle (MC) on training and competition performance, and (2) to explore female cyclist’s comfo...
Correction: Validation of the Arabic Levels of Emotional Awareness Scale (LEAS-Arb)
Exploring translator’s style in children’s literature: A case study of Nicky Harman’s English translations of Huang Beijia’s two works
Huang Beijia’s contemporary Chinese novels Wo Yao Zuo Hao Hai Zi (a contemporary realistic children’s novel, 1996) and Ye Feng Fei Wu...
A data-driven framework for modeling the dendritic spine continuum using dimensionality reduction and clustering toward understanding synaptic plasticity
Dendritic spines are dynamic extensions of dendrites that change in shape and distribution in response to neuronal activity, playing central roles in memory and learning. Computational methods are wid...
Current use of specific wearables and factors that would motivate future use of wearables: Results based on the general German adult population
Background A conscious use of wearables may be beneficial for health in general. Therefore, we aimed to investigate the current use of specific wearables and factors that would mot...
Correction: Oropouche infection in Peruvian patients: A systematic review and meta-analysis
Metabolomics-constrained modelling reveals dominant oxidative metabolism in the Egyptian fruit bat myocardium
Aim The present study aimed to elucidate which pathways contribute to cardiometabolic adaptation in Egyptian fruit bats. M...
Parenteral nutrition in advanced cancer: A qualitative study on decision-making and information needs of patients and carers
Objectives To identify the information needs of people with advanced cancer, and their carers, to make an informed decision to commence or discontinue parenteral nutrition (PN)....
Prerequisites and challenges of the role played by death Doula for supporting patients with cancer in end-of-life (EOL) stages: Qualitative study
End-of-life (EOL) doulas support dying people and their families. They are a response to the expectations of healthcare professionals (including palliative care providers) in end-of-life situations.Th...
Advanced persistent threat detection through multi-modal behavioral analysis
Advanced Persistent Threats (APTs) represent sophisticated cyberattacks characterized by stealth, persistence, and evasion of traditional detection mechanisms. We observed that APT behaviors during la...
Modeling of solid oxide fuel cells and optimal parameter extraction at various operating data using an optimization method
One promising technology for a clean and effective energy conversion option is the solid oxide fuel cell (SOFC) being developed for a broad, widespread role in mobile equipment power supply, and stati...
Transcriptome sequencing combined with experimental verification to explore potential key genes related to uric acid in diabetic retinopathy
Purpose Diabetic retinopathy (DR), a major microvascular complication of diabetes and leading global blindness cause, involves uric acid (UA) in its onset and progression. This stu...