PLoS ONE
Articles in this Issue
Integrated hierarchical surface restructuring of assembled electrode arrays for next-generation neural interfaces
Neurostimulation devices rely on electrode arrays to deliver targeted electrical stimulation for modulating nerve activity. Enhancing stimulation specificity, device battery and energy efficiency, and...
Integrating network toxicology, machine learning, and single-cell sequencing to reveal the FASN-mediated role of phenolic endocrine disruptors in water in promoting prostate cancer
Background Phenolic endocrine-disrupting chemicals (EDCs) like nonylphenol (NP) and octylphenol (OP) are widespread water pollutants. Their estrogen-like properties are suspected c...
Expression of Concern: Regulation of PKC Mediated Signaling by Calcium during Visceral Leishmaniasis
Development of a Confined-Space Suitability Index (CSSI) using Least Absolute Shrinkage and Selection Operator (LASSO) regression: a pilot study for structured fitness-for-duty screening
Background Confined space work exposes workers to complex risks, including oxygen deficiency, hazardous gases, and physical strain, requiring structured criteria for fitness-for-du...
Pharyngocutaneous fistula after total laryngectomy: Prevalence and risk factors
Objective To determine the prevalence and identify associated risk factors of pharyngocutaneous fistula following total laryngectomy....
Exploring primary care health professionals’ perceived influence of their communication on HPV vaccine acceptance: Results from a national survey
Objective To evaluate primary care health professionals’ (PCHPs) perspectives on how their communication influences HPV vaccine acceptance, based on the self-perception theory. And...
Imaging the impact of rotifer consumption on bacterial behaviors in the zebrafish gut
The gut microbiota influence many aspects of their host’s health and physiology including the digestion of food, and food intake in turn influences the composition of the gut microbiome. However, the...
On the crossroads of interdisciplinary medicine in amyloidosis – study protocol for a single-center interdisciplinary registry study
Background Systemic amyloidosis comprises a heterogeneous group of rare diseases characterised by extracellular deposition of misfolded protein fibrils, leading to progressive orga...
Retraction: Prediction of thermal distribution and fluid flow in the domain with multi-solid structures using Cubic-Interpolated Pseudo-Particle model
An AI-driven fire risk forecasting framework for urban villages using IGWO-optimized LSTM with incremental learning
Artificial intelligence (AI) is reshaping decision-support systems across multiple domains, including risk management and urban safety. Urban villages, characterized by high population density and inf...
Pricing strategies of the tobacco companies in response to cigarette excise tax increases in Montenegro
This study examines the impact of excise tax increases on cigarette prices in Montenegro, offering insights into the tobacco industry’s pricing strategies. Using both panel quantile regression and fix...
Retraction: Molecular separation of ibuprofen and 4-isobutylacetophenone using octanol organic solution by porous polymeric membranes
Burden of acute lymphoblastic leukemia in children and adolescents in low- and middle-income countries from 1990 to 2023 and projections to 2050: A systematic analysis from the global burden of disease study 2023
Background Acute Lymphoblastic Leukemia (ALL) is the most common and curable malignancy in children and adolescents, yet it remains a significant health threat. Despite global surv...
A Lipoxygenase 3 mutation reverses growth phenotypes in an Arabidopsis Plastid Lipase 3 overexpression line
Plastid Lipase 3 (PLIP3) is a chloroplast phospholipase A that cleaves linolenic acid, a polyunsaturated fatty acid, from the sn -1 position of the chloroplast...
Tumor hypoxia is associated with global copy-number alteration burden and subtype-dependent overall survival in breast cancer: Evidence from TCGA and METABRIC
Tumor hypoxia is biologically important in breast cancer, but its prognostic value may be distorted by intrinsic molecular subtype composition. This study evaluated whether hypoxia-related prognosis w...
A low-cost markerless motion capture system to automate functional gait assessment: Feasibility study
Functional gait assessments in older adults have traditionally required manual in-person quantification of clinical measures such as walking speed and step placement. This reliance on individuals trai...
Economic barriers to diagnostic equity: A multi-country analysis of patient costs for rapid SARS-CoV-2 testing in sub-Saharan Africa
While the acute phase of the COVID-19 pandemic has passed, understanding the economic barriers to diagnostic access remains critical for future pandemic preparedness and universal health coverage. Imp...
Correction: Impact of different blood pressure targets on cerebral hemodynamics in septic shock: A prospective pilot study protocol—SEPSIS-BRAIN
CACE closed: A multiverse examination of the influence of implementation variability on student outcomes in a randomised controlled trial of a universal, school-based social-emotional learning intervention
Introduction Amidst calls for more high-quality research to assess the influence of implementation variability on student outcomes in school-based trials using instrumental variabl...
ProtAttn-QuadNet: An attention-based deep learning framework for protein–protein interaction prediction using ProtBERT embeddings
Protein–protein interactions (PPIs) form the backbone of most cellular processes, governing signal transduction, gene regulation, and metabolic control. However, experimental approaches to identifying...
Expanding diversity of tick-borne phleboviruses (Phlebovirus mukawaense, Mudanjiang phlebovirus, Gomselga Virus, and Onega tick phlebovirus) in Russia
Tick-borne phleboviruses represent emerging pathogens with zoonotic potential, yet their distribution across Asian Russia remains poorly characterized. This study investigated the prevalence, genetic...
Can immersive virtual reality magnify treatment outcomes of computerized script training on Cantonese speakers with chronic aphasia? Protocol of a randomized controlled trial
Background Aphasia persists in 20% of the stroke population. Speech therapy has been suggested to benefit the functional communication of people with aphasia (PWA). Virtual reality...
Identification of métiers in a multi-gear, multi-species fishery
Accurate, gear-specific data is essential for fisheries management to quantify fishing pressure and ecosystem impacts, particularly in multi-gear fleets. In this study, we used electronic logbooks and...
The pivotal role of social identification in explaining authentic leadership’s effect on team organizational citizenship behavior
Purpose The potential for authentic leadership to influence team organizational citizenship behavior (OCB) brings questions regarding the mechanisms underpinning such an effect int...
Associations between body composition and gut microbiota in female college students with and without dance training
Physical activity has been associated with gut microbiota variation and body composition phenotypes, but evidence in female dance students remains limited. This study compared body composition profile...