PLoS ONE
Articles in this Issue
Data subdivision approach enhances machine learning-based mortality prediction in pediatric ICU patients
Objective To evaluate machine learning–based models for predicting all-cause mortality in pediatric ICU patients using comprehensive biochemical panels, with a focus on addressing...
Preparation and in vitro evaluation of photodynamic-responsive nanoliposome loaded PL-5
Burn wound infections are frequently complicated by biofilm-forming and multidrug-resistant pathogens, particularly methicillin-resistant Staphylococcus aureus (MRSA), posing major therapeutic challen...
Understanding participants’ experiences of a behaviour change intervention within cardiac rehabilitation: A nested process evaluation within the STRENGTH randomised controlled trial
Background The STRENGTH (Self-management and Theory-based Rehabilitation Encouraging New Gateways to Healthy-Hearts) study evaluated a behaviour change intervention embedded within...
Transcatheter and surgical aortic valve replacement for aortic stenosis in France: Trends from 2010 to 2022 and impact of European guidelines and clinical trial results
Background The PARTNER trials played a key role in the expansion of transcatheter aortic valve replacement (TAVR) for severe aortic valve stenosis (AS), shaping international pract...
Markov modeling in R: Advanced method using a cost-effectiveness analysis
A Markov model is the kind of state transition model most widely used in Health Economic Evaluation (HEE) to analyse the efficiency of an intervention and support decision-making. However, it is has t...
Vaccine management systems with a focus on cold chain management and delivery of immunization services in low- and middle-income countries: A scoping review
Objective The main objective of this scoping review is to examine the characteristics of vaccine management and delivery systems with a specific focus on cold chain management used...
A two stage statistical framework for cold start spare part demand forecasting
Accurate demand forecasting for spare parts under true cold-start conditions remains a fundamental challenge due to extreme demand sparsity, zero inflation, and the complete absence of historical dema...
Research on the influencing factors and mechanism of AR e-commerce consumers’ purchase intention
Against the backdrop of the digital economy and the increasing integration of virtual and physical consumption scenarios, augmented reality (AR) e-commerce reshapes the shopping experience by overlayi...
EMP: Enhanced Multi-modal Prediction for fashion sales using Fourier Mapping and ERP-based contrastive learning
Predicting sales for newly introduced fashion products presents a significant challenge due to the absence of historical data and the inherently multi-modal nature of the inputs. To address this issue...
Editorial Note: “In Weapons We Trust?” Four-culture analysis of factors associated with weapon tolerance in young males
Navigating the unspoken: A qualitative study of employees’ perceptions of culture and norms surrounding sexual harassment at a Swedish university
Sexual harassment persists in academic workplaces despite extensive policy frameworks. This study explored how employees at a large Swedish university perceive and articulate the organisational cultur...
Student-teacher agreement on personality traits and social competencies during early adolescence: A longitudinal study
The present study sought to validate existing knowledge on inter-rater agreement on personality traits and social competencies. Based on longitudinal data, the study aimed to determine whether the agr...
Calcitonin as an adjunct for phantom limb pain
Objective This retrospective study evaluated calcitonin as an adjunct therapy for reducing phantom limb pain (PLP) following lower limb amputation....
Benchmark of biomarker identification and prognostic modeling methods on diverse censored data
The practices of identifying biomarkers and developing prognostic models using genomic data has become increasingly prevalent. Such data often features characteristics that make these practices diffic...
The evolution of life size Barbie and Ken: Are they any closer to reality?
Barbie and Ken dolls have been criticized over time for their overt misalignment of body shape in comparison with the average adult, and the possibility that this impacts the formative minds of childr...
Factors associated with low-level viremia in people living with HIV: A 10-year retrospective study in South Korea
Purpose The goal of antiretroviral therapy is to achieve and sustain the suppression of human immunodeficiency virus (HIV) viral load. In this study, we aimed to identify risk fact...
Outcomes of school-aged children following traumatic brain injury from road traffic accidents in Malaysia: A retrospective study
Background Traumatic brain injury (TBI) resulting from road traffic accidents (RTAs) is a leading cause of morbidity in children globally. However, paediatric TBI outcomes are unde...
Correction: Intravenous thrombolysis for acute central retinal artery occlusion: Protocol for a systematic review and individual participant data meta-analysis of randomized controlled trials
The experiences of doctors in Lesotho during the COVID-19 pandemic: A qualitative study
The COVID-19 pandemic dramatically increased pressure on healthcare staff who were trying to manage and adjust to the novel situation. For many healthcare workers, this came at a cost to their wellbei...
Butorphanol decreased the median effective concentration of ropivacaine in ultrasound-guided interscalene brachial plexus block
Background Combining butorphanol with local anesthesia can enhance the analgesic effect of local anesthesia and prolong the duration of action for nerve block anesthesia. In this s...
Symptom profiles and health-related quality of life in Korean adults with post-acute sequelae of SARS-CoV-2 infection (PASC): A latent profile analysis
Background Post-Acute Sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (PASC) is characterized by persistent and heterogeneous symptoms that impai...
Correction: Molecular Genetic Analysis of 103 Sporadic Colorectal Tumours in Czech Patients
Machine learning approaches for predicting preventive maintenance costs of expressways in Xinjiang
With the expansion of high-speed road mileage and the aging of road networks, maintenance workloads have increased dramatically. Accurately forecasting preventive maintenance costs is a practical appr...
Digital media pattern design compression and optimization method based on K-means clustering and LLE dimensionality reduction
The rapid development of digital media demands higher quality in pattern design. Simultaneously, significant redundant information hinders the transmission and sharing of these patterns, creating an u...
Cost-effectiveness of pre-emptive pharmacogenetic testing: An umbrella review
Background Consortia have been established and published pharmacogenetic-specific guidelines with pharmacotherapeutic recommendations. While these consortia and their guidance addr...