PLoS ONE
Articles in this Issue
Expression of concern: Phyto-ecological studies and distribution pattern of plant species and communities of Dhirkot, Azad Jammu and Kashmir, Pakistan
Choices and options in the care procurement process of bundled payment contracts: A literature-based overview from a payer’s perspective
Context While the potential of bundled payment models to facilitate value-based care is hard to overestimate, the complexity of designing an effective and feasible care procurement...
Organized community sport participation for children and youth with physical disability: A scoping review protocol
Children and youth living with physical disability have less opportunities to participate in organized meaningful physical activities in their communities than their typically developing peers. Equita...
The ARGO dataset: Annotated and delineated intracardiac electrograms of post-ischemic ventricular tachycardia
The identification of abnormal ventricular potentials (AVPs) in intracardiac electrograms of post-ischemic ventricular tachycardia patients is challenging, and the development of automated tools is ha...
Assessing body position through experimental cremation: A pilot study using colorimetry and FTIR-ATR analyses
This pilot study evaluates the feasibility and limitations of a multi-proxy approach for identifying potential indicators of horizontal positioning in cremated heads from archaeological, and to a less...
The effectiveness of a foot-care education program based on multi-theory model in diabetic patients with risk of foot ulceration: A randomized controlled trial protocol
Background Diabetic foot ulcer (DFU) is one of the most common and serious complications of diabetes mellitus (DM). The high disability and fatality rates of DFU raise the importan...
The chain-mediating role of caregiver burden and illness uncertainty between social support and preparedness among family caregivers of spinal cord injury patients
Objective This study aimed to examine the effects of social support, caregiver burden, and illness uncertainty on preparedness among family caregivers of individuals with spinal co...
A scoping review of computational models of the diabetic foot
The prevalence of diabetes is expected to be 650 million people by 2030, and diabetic foot ulceration (DFU) is one of its most severe complications. It poses a significant challenge to global health a...
Speed, slope, and synchrony: Empirical insights into SAR searcher behavior
Wilderness search and rescue (SAR) missions are time-critical and terrain-dependent, so planners must quickly allocate resources across complex landscapes. In practice, they rely on expert judgment an...
Phonological awareness in Urdu language speaking children with down syndrome (DS)
Introduction Phonological awareness (PA) is a vital part of literacy development. With dearth of evidence on phonological processing among Urdu-speaking children with down syndrome...
Structure-based pharmacophore modeling, high-throughput screening, and molecular dynamics identify a novel DrugBank-derived HIV-1 protease inhibitor
HIV-1 protease (PR) is required for viral maturation and is a major antiretroviral target. In this study, a structure-based pharmacophore modeling, drug repurposing, docking, and molecular dynamics (M...
Using mixed reality to support component restoration of Chinese traditional dwellings: A case study of column bases in Yanling House
Due to limited surveying, mapping, and image data, as well as technological constraints, current efforts to restore missing components in traditional Chinese dwellings often result in mismatches with...
Trends in recorded deaths involving antipsychotics: The role of deprivation, ethnicity, and regional disparities
Objective The relationship between antipsychotic use and mortality remains uncertain, with evidence suggesting both potential risks and benefits. This study aimed to examine trends...
Altered brain–behavior coupling during inhibitory control in ankylosing spondylitis: ERP evidence from NoGo-P3 component
Background Cognitive dysfunction has increasingly been recognized in Ankylosing Spondylitis (AS), yet the neural mechanisms underlying inhibitory control in this population remain...
Unraveling Puerarin’s impact on MRI hepatic lipid deposition and serum lipids in IUGR offspring rats
Intrauterine growth restriction (IUGR) is associated with long-term metabolic programming effects, including hepatic structural alterations and later-life susceptibility to metabolic disease, potentia...
Comparison of self-collected vaginal swabs and first-void urine for detection of human papillomavirus in sexually active girls and women in three South Asian countries
Background As more countries plan and launch human papillomavirus (HPV) vaccination campaigns, a variety of self-sampling methods and assays have been used for detecting high-risk...
HPA-UNet-LSNet: An LSNet-based U-Net with hybrid pooling attention for accurate segmentation of Haloxylon ammodendron crowns from UAV RGB imagery
Accurate segmentation of Haloxylon ammodendron crowns from UAV RGB imagery remains challenging in desert environments because of sparse crown distribution, weak...
“Picking the right person … can make or break the whole deal”: Development of a layperson injector selection tool for administration of home-based long-acting injectable antiretroviral therapies
Background Clinic-based administration of long-acting injectable antiretroviral therapy (LAI-ART) is resource-intensive and may exacerbate disparities in access to care. Home-based...
Drug-induced gastric motility disorders: A disproportionality analysis from the FAERS and CVARD databases
Background Delayed gastric emptying and gastroesophageal reflux represent critical yet frequently underrecognized complications in hospitalized patients, particularly in the contex...
Correction: Efficacy and safety of the ayurvedic formulation ‘Trikatu’ as an add-on to standard care in dyslipidemia: Study protocol for a randomized, double-blind, placebo-controlled trial evaluating lipid parameters, and gut microbiota
Dynamic analysis of critical maternal complications in tertiary hospitals in Wuxi: A study based on four years of monitoring data
Background Severe maternal morbidity (SMM) is a significant public health concern. This study analyzed the incidence, trends, causes, and pregnancy outcomes of SMM in Wuxi to infor...
THSD7B promotes tumor progression and is associated with prognosis in gastric adenocarcinoma
THSD7B (thrombospondin type-1 domain-containing 7B) has been implicated in several malignancies; however, its role in gastric adenocarcinoma remains unclear. This study aimed to investigate the expres...
Editorial Note: Soil quality indicator-based land productivity modelling for agricultural sustainability
State and federal policies and school meal participation: A descriptive analysis from Arizona
Starting in 2023, the state of Arizona implemented a series of policies to improve access to school meals: (1) A state policy to eliminate co-pays for reduced-price meals, implemented in January, 2023...
KYNU in macrophages contributes to the unique immune feature of LUAD via integrating single-cell and bulk RNA sequencing data: an exploratory analysis
Background Lung adenocarcinoma (LUAD) is a predominant subtype of lung cancer associated with an unfavorable prognosis. However, the roles of the tumor microenvironment (TME) and K...