PLoS ONE
Articles in this Issue
Acute kidney injury severity in ICU patients: Developing and evaluating a data-driven analysis of clinical covariates using machine learning
Background Acute kidney injury remains a major cause of morbidity and mortality in critically ill patients. Existing classification systems rely on serum creatinine and urine outpu...
Organizational factors influencing recreational therapy program effectiveness in veterans’ nursing homes: A mixed-methods approach
Background Veterans’ nursing homes face significant challenges in delivering effective recreational therapy (RT) programs due to complex organizational factors and unique veteran c...
Characterization and functional analysis of miRNAs in Salvia miltiorrhiza-isolated exosome-like nanoparticles for gastric cancer treatment
Background Gastric cancer (GC) is a widespread global malignancy, frequently diagnosed at advanced stages owing to the subtle nature of early symptoms and low screening rates. Cons...
Rumination and subjective well-being: The chain mediating role of emotion regulation difficulties and problematic social media use
Objectives Based on the Compensatory Internet Use Model and the I-PACE framework, the present study develops a serial mediation model grounded in a cognition-emotion-behavior pathw...
Latent classes and predictors of aggression trajectories in Korean adolescents: Implications for targeted prevention
School violence and juvenile crime are emerging social problems in Korea. Adolescent aggression, an important mediator linking risk factors in the developmental environment to more serious deviant beh...
PyPeCT2S: Pythonic paediatric computed tomography to strength with automatic landmarking for the automation of bone strength analysis in children
Quantitative computed tomography (QCT) based finite element analysis (FEA) models have been used to accurately predict bone strength. However, the process is time-consuming and requires a trained prof...
Using nominal group technique to select an HIV status disclosure decision aid for adaptation in Georgia
Introduction HIV status disclosure decision-making is a complex process influenced by stigma, relationship dynamics, and anticipated social consequences. Although decision aids can...
Efficient and lightweight long-range modeling for 3d point cloud classification and segmentation
3D point clouds, with their compact structural representation and rich geometric information, have become fundamental data sources for visual understanding tasks in computer vision, robotics, and inte...
Projected climate change effects on suitable habitat for Pseudosuccinea columella and Radix natalensis in uMgungundlovu, South Africa
Introduction Climate change impacts oceanic and atmospheric circulation patterns, precipitation, air and sea surface temperatures leading to altered intermed...
Epidemiology and clinical features of Hymenoptera stings in East Azerbaijan, northwestern Iran
Background Stings caused by Hymenoptera including honey bees, wasps, and hornets represent a growing global and national health concern with outcomes ranging from mild local reacti...
A novel deep-learning approach for robust identification of plant diseases
Rising temperatures and changing weather conditions are accelerating the spread of plant diseases and increasing the threat to global food security. Reliable detection of leaf diseases is therefore es...
Lifetime HIV testing frequency among women in Sub-Saharan Africa: A DHS-based analysis using zero-inflated negative binomial regression
Background HIV testing is an essential component of HIV prevention and care, yet lifetime testing frequency remains low in sub-Saharan Africa (SSA). This study examines the factors...
Unraveling uneven urbanites’ expressed happiness across Chinese cities using geotagged social media data: Key predictors and future climate–happiness associations
Understanding inter-city disparities in urban expressed happiness (EH) and the key predictors for these differences is critical for advancing socially sustainable urban development. However, the key p...
Protocol for a quasi experimental mixed method study on impact of intervention for improving Infant and Young Child Feeding (IYCF) practices in tribal block of Palghar District, Maharashtra, India through involvement of frontline workers
Introduction Infant and Young Child Feeding (IYCF) is crucial for child growth, especially in the first two years. Despite various government initiatives, nearly 35.5% of under-fiv...
Cross-cultural assessment of knowledge and attitudes toward Folic acid: Instrument development and validation in Thailand and Yemen
Folic acid is essential for the prevention of neural tube defects and other congenital anomalies, yet awareness and uptake vary across cultural and resource settings. Reliable tools to assess women’s...
Trap tales: The influence of red alder stand conditions and forest fragmentation on family-level beetle bycatch diversity
Beetle (Coleoptera) bycatch from insect traps can provide insights into forest health and biodiversity trends. Red alder, Alnus rubra , a nitrogen-fixing tree t...
Reliability and validity of the individual GPS game data–based maximal acceleration–initial running speed regression line in youth elite soccer players
Modern load monitoring in soccer increasingly employs relative individualized acceleration intensity thresholds derived from individual maximal acceleration–initial running speed (a...
Effects of seedling age at transplanting on root-shoot traits and yield in direct-seeded maize
To address weak growth and low yield of spring maize under transplanting and seedling replacement, this study evaluated the effects of transplanting at different seedling ages on dry matter production...
Integrated assessment of thiram toxicity in pangasius fish: Erythrocytic abnormalities, gill and intestinal defense mechanisms, and genotoxicity
Pesticides play a crucial role in agriculture, public health management, and veterinary practice to control pests. However, the persistent use of pesticides poses a significant threat to aquatic ecosy...
Calibrated early-warning models with fairness auditing and selective prediction for course withdrawal risk: Evidence from OULAD
Early-warning systems (EWS) in learning analytics are increasingly used to identify learners at risk of course withdrawal, but their deployment-critical properties are often under-reported once predic...
Prevalence and pre-disposing factors of Helicobacter pylori among patients with gastro-intestinal symptoms attending Mulago Hospital, Kampala, Uganda
Background Comprehensive data on the prevalence of Helicobacter pylori infection and its predisposing factors amo...
Pediatric Capacity Building in Northern Laos: An Evaluation of the Pediatric Nursing Training Program at Lao Friends Hospital for Children
Background In 2015, the child mortality rate in Laos was 53.6 per 1,000 live births. The Lao Friends Hospital for Children (LFHC) in Luang Prabang was established to enhance access...
Tail risk, large fluctuations and downfalls in renewable energy markets
The renewable energy sector has expanded rapidly as countries pursue decarbonization goals, increasing investor exposure to market risk and extreme price movements. While prior research has examined d...
An explainable artificial intelligence framework for clinical decision support in stroke discharge planning
Background Stroke, a leading cause of global mortality and disability, requires accurate prediction of discharge outcomes to support early care planning. We developed an explainabl...
From environmental concerns to nationalist waves: Mapping the evolving Fukushima wastewater discourse on Weibo
This study employed Structural Topic Modeling (STM) on 56,526 Weibo posts to examine the evolving discourses surrounding the Fukushima wastewater release. While rational discourse focusing on technica...