PLoS ONE
Articles in this Issue
Construction and empirical analysis of a quantitative model on the relationship between budget control and financial performance in management accounting—Evidence from Russian enterprises
Currently, many enterprises face issues in budget management, such as superficial budgeting, lax execution, and insufficient feedback, leaving the mechanism linking budgetary control and financial per...
Multicenter evaluation of BACT-Info. and an infection algorithm using Urine Flow Cytometry among clinically diagnosed UTI patients in Indonesia
Urinary tract infections (UTIs) are the most common infections in both outpatient and inpatient settings, contributing significantly to morbidity, reduced quality of life, and antimicrobial overuse. A...
Machine learning-enhanced 3GPP channel modeling for 5G networks: A vendor-calibrated framework with cross-scenario validation
Accurate channel characterization across diverse propagation environments is foundational to 5G network planning, yet existing machine learning approaches rarely integrate standardized 3GPP frameworks...
Exploring cost trajectories of patients admitted to short-term residential care in the Netherlands
Objective Short-term residential care (STRC) is a Dutch form of post-acute care intended to return older adults home to live independently, yet fewer than 55% of patients are disch...
Likweli: A remarkable new species of Colobus monkey from the Lomami National Park, Democratic Republic of Congo
We describe and name a new species of African monkey, Colobus congoensis sp. nov. (Primates, Cercopithecidae), from the interfluve region of the Lomami and Cong...
Expression of Concern: Alcohol Dehydrogenase Protects against Endoplasmic Reticulum Stress-Induced Myocardial Contractile Dysfunction via Attenuation of Oxidative Stress and Autophagy: Role of PTEN-Akt-mTOR Signaling
ViT-MultiRAGNet: A scalable and reliable retrieval-augmented Vision Transformer framework for memory-guided feature fusion multi-modal mammogram classification
Background Diagnosing breast cancer with mammography continues to be an incidentally challenging process because of the numerous different ways of acquiring the images, the vast di...
Maternal knowledge of obstetric danger signs and related factors among antenatal care attendees in Hargeisa, Somaliland: A cross-sectional analysis
Background Maternal mortality remains a major global health challenge, disproportionately affecting low- and middle-income countries. Despite international efforts, nearly 95% of m...
Optimization of injection molding parameters for bending and tensile strength of ABS and ABS/carbon fiber composites using Taguchi–Grey correlation analysis
This study investigates the effects of injection molding parameters on the flexural and tensile strengths of neat acrylonitrile–butadiene–styrene (ABS) and woven carbon fiber fabric–reinforced ABS com...
Interoceptive autonomic regulation in typical development and autism spectrum disorder: A computational model integrating multiple physiological systems
Background Interoceptive cardiovascular signals, including heart rate (HR) and blood pressure (BP), arise from coordinated sympathetic (SNS) and parasympathetic (PSNS) regulation a...
Examining the feasibility and preliminary effects of resistance exercise training and creatine supplementation in individuals treated for colorectal cancer
Purpose The purpose of this trial was to assess the feasibility, acceptability and safety of a 10-week hybrid (in-clinic and virtual) resistance exercise training RET program with...
Impact of blood pressure control during pregnancy on long-term maternal cardiovascular health – secondary analysis of a follow-up study 15 years post preeclampsia (PAVA study)
Background Within the PAVA study, we investigated placenta-associated vascular aging in women 15 years after pregnancies complicated by preeclampsia and/or fetal growth restriction...
Mesothelial cells derived extracellular vesicles promote angiogenesis through the transfer of angiopoietin-2
Background Peritoneal mesothelial cells play a critical role in shaping the peritoneal tumor microenvironment and are increasingly recognized as active regulators of angiogenesis i...
Comprehensive evaluation of an emergency monovalent SAT1 foot-and-mouth-disease vaccine: Antigen quality, product consistency, and protective efficacy
Foot-and-mouth disease (FMD) remains endemic in Egypt, with periodic incursions of antigenically distinct virus lineages. In 2025, FMDV serotype SAT1/topotype I was detected in Egypt for the first tim...
Research on design of soft gripper by dielectric elastomer actuator based on quadrangular star honeycomb support
This study proposes a soft gripper with dielectric elastomer actuator (DEA) and 3D printing quadrilateral star honeycomb support due to the insufficient structural stiffness when grasping irregular ob...
Chronic disease related emergency department presentations and potential for redirection to alternative acute care settings (“FOCUS” study): A nationwide flashmob study
Background Emergency Departments (EDs) face increasing pressure, driven in part by the complex needs of an ageing population. Many internal medicine ED visits may reflect complicat...
Predicting ankylosing spondylitis disease activity via patient-reported outcome measures: Building prediction models based on machine learning
Objective Disease activity is a critical indicator for monitoring the progression of ankylosing spondylitis (AS), guiding clinical decision-making, and informing treatment plans. P...
Acute Cordyceps militaris supplementation and elevated resting oxygen uptake with faster reaction times: A randomized crossover trial
Background Cordyceps militaris (CM) demonstrates neuroprotective properties in chronic preclinical models, but its acute effects on cognitive and physiological parameters during ex...
A study on the car-following model for mountainous curves incorporating driving behavior characteristics
This study addresses the high accident rate on mountainous highways, driven by complex road alignments, harsh climatic conditions, and heterogeneous driving behaviors, aiming to enhance the accuracy o...
Vicia faba-PGPB association improves soil health as a sustainable strategy to remediate moderately Pb and Cd contaminated soils
Phytoremediation is an eco-friendly strategy for heavy metal bioremediation. This study focuses on assessing the potential of faba bean- plant growth promoting bacteria symbiosis in phytoremediation a...
Identification of tooth traces from a Cretaceous (Maastrichtian) Edmontosaurus annectens bonebed in the Lance Formation, Wyoming, U.S.A.
Identifying the origin of perforating lesions on fossil bone is often difficult, and many are considered tooth traces, in spite of more likely and more parsimonious etiologies. Much of this confusion...
Binding Affinity Ranking at the Molecular Initiating Event (BARMIE): An open-source computational pipeline for the rapid screening of chemical interactions with steroid receptors from many species
A challenge in ecological risk assessment is identifying the chemicals that pose the greatest threat and determining which species are most vulnerable to them. To help address this, this study has dev...
Concentrations of essential and non-essential elements in eastern North Pacific killer whales (Orcinus orca)
Essential and non-essential elements can harm marine wildlife and impact ecosystems. Using liver (n = 35) and kidney (n = 17) samples from 35 animals from three distinct killer whale (...
MamNet-PT: A Mamba-enhanced hybrid architecture with selective state-space modeling for uncertainty-aware brain tumor segmentation
Precise segmentation of brain tumors from MRI remains a challenging problem in medical image analysis because tumor regions exhibit substantial size variability, diffuse and infiltrative boundaries, a...
The AHS-R: A holistic thinking measure with expanded theoretical domains and improved score reliability
Analytic and holistic thinking represent distinct cognitive styles. The existing Analysis-Holism Scale (AHS) is the most widely used measure of holistic thinking but has faced psychometric challenges...