PLoS ONE
Articles in this Issue
Healthcare utilization during acute medically attended episodes of respiratory syncytial virus-related lower respiratory tract infection among infants in the United States
Background Respiratory syncytial virus (RSV) is the leading cause of infant hospitalization in the United States. Understanding healthcare utilization associated with medically attended (MA) RSV lower...
Modelling protein-protein interactions for the design of vaccine chimeric antigens with protective epitopes
Ticks and tick-borne diseases are a growing burden worldwide and vaccines are effective control interventions. Vaccine formulations with tick antigens such as BM86/BM95 (BM) and Subolesin (SUB) have s...
Patient perceived weight stigma and patient-centered language use preferences: A cross-sectional mixed methods analysis conducted in a large academic medical center
Background Due to the rising prevalence of obesity and its impact on healthcare, patient-specific context is needed to optimize weight management with an emphasis on reducing health care-associated we...
The recombinant spike S1 protein induces injury and inflammation in co-cultures of human alveolar epithelial cells and macrophages
The current lack of a straightforward and convenient modeling approach to simulate the onset of acute lung injury (ALI) has impeded fundamental research and hindered the screening of therapeutic drugs...
Where is communication breaking down? Narrative tensions in obesity-in-pregnancy clinical encounters
There are numerous biomedical and psychosocial challenges associated with obesity in pregnancy that impede communication between healthcare providers (HCPs) and patients. We conducted a narrative stud...
Does patients’ age predict their clinical outcomes following non-infectious epiglottitis? A systematic review
Background Non-infectious epiglottitis, an infrequent but significant condition, presents challenges in airway management and treatment due to its potential for rapid progression. Objective To analy...
Bivariate multilevel modeling of antenatal care contacts and place of delivery among reproductive-aged women in Ethiopia
Background Antenatal care (ANC) contacts, along with enhanced health facilities for delivery, are essential components of maternal and child healthcare, as these significantly contribute to both mothe...
Research on the construction of a sustainable scientific research capability evaluation model for university teachers based on the T-S fuzzy neural network
Introduction This study aims to enhance educational quality and academic standards by proposing a model based on critical research ability indicators to objectively evaluate the sustainable scientific...
Gains vs losses in pay-for-performance: Stated preference evidence from a U.S. survey
Background Pay-for-performance (P4P) incentives can be paid as a bonus (gain) or a penalty (loss). Diminishing marginal utility of wealth suggests that, starting from the same initial wealth, individu...
Research on intelligent routing with VAE-GAN in the internet of body
The "Internet of Body" is an emerging technology that is centered on the human body and connected to the Internet. It can monitor a variety of human data (such as heart rate, blood oxygen content, etc...
Modeling daily evapotranspiration time series based on Non-Linear Autoregressive Exogenous (NARX) method and climate variables for a data-deficient region
For flood-prone, developing nations where hydrological data is scarce, an innovative methodological approach is essential. This study aims to explore the potentiality of modelling daily evapotranspira...
PCK1 and SLC22A2 gene variants associated with response to metformin treatment in type 2 diabetes
Type 2 diabetes (T2D) is a chronic disorder affecting 462 million worldwide, often managed with metformin as first-line treatment. However, metformin’s response varies among individuals, including up...
Effect of dietary anthocyanins on the risk factors related to metabolic syndrome: A systematic review and meta-analysis
Objective This meta-analysis aims to systematically investigate whether dietary anthocyanin supplementation can reduce metabolic syndrome (MetS)-related risk factors: abdominal obesity, dyslipidemia (...
User experience with pregnancy tracker mobile apps: Findings from comment-based qualitative study
Background Worldwide, millions of pregnant women use pregnancy-related apps to monitor their baby’s growth and development. While most of the apps are user-friendly, not all of them are equally appeal...
The effects of L-carnitine and fructose in improved Ham’s F10 on sperm culture in idiopathic severe asthenospermia within 24h
To study the effects of L-carnitine and fructose on semen parameters of severe asthenospermia patients by sperm culturing in vitro within 24h. We optimized the energy composition and antioxidant subst...
The effects of flight training on flying cadets’ brain structure
In recent years, the impact of professional training on brain structure has sparked extensive research interest. Research into pilots as a high-demand, high-load, and high-cost occupation holds signif...
Addressing imbalanced data classification with Cluster-Based Reduced Noise SMOTE
In recent years, the challenge of imbalanced data has become increasingly prominent in machine learning, affecting the performance of classification algorithms. This study proposes a novel data-level...
On the hedge and safe-haven abilities of bitcoin and gold against blue economy and green finance assets during global crises: Evidence from the DCC, ADCC and GO-GARCH models
This paper investigates the diversification, hedging, and safe-haven capabilities of Bitcoin and gold against blue economy and green finance assets using three different MGARCH models (DCC, ADCC, and...
Blueprint for progress: Understanding the driving forces of BIM adoption in Kingdom of Saudi Arabia (KSA) construction industry
Building information modeling (BIM) as a virtual and digital mode of representing construction activities gained significant attention and facilitated construction projects. Nevertheless, many driving...
Implementation and first report of the Brazilian Kidney Biopsy Registry
Background Kidney biopsy registries are valuable tools for guiding clinical practice and developing health policies. In 2021, the Brazilian Society of Nephrology (SBN) created the Brazilian Kidney Bio...
Olympic combat sports and mental health in children and adolescents with disability: A protocol paper for systematic review
Introduction Mental health is important for children and adolescents, particularly those with disabilities. While the mental health advantages of sports participation are well-documented, the specific...
The accuracy of capture per unit effort in predicting density of a cryptic snake was more sensitive to reductions in spatial than temporal coverage
A critical component of monitoring wildlife populations is understanding changes in population size or abundance. However, for most populations a complete census is not possible; thus, trends or abund...
Metarhizium mendonceae sp. nov.: An important biological control agent for insect pests
The Metarhizium anisopliae complex consists of 34 formally described phylogenetic species. Metarhizium anisopliae sensu lato has been used for decades in Brazil as a biological control agent for contr...
Effects of outdoor play on body composition and physical performance in children: the Yamanashi Adjunct study of the Japan Environment and Children’s Study
Introduction Childhood is a pivotal developmental stage that substantially affects lifelong habits. Recent research has emphasized the vital role of outdoor play in children’s mental and physical well...
Flowing between gongs: Mixed-methods insights into shared flow and temporal distortion in music performance
Ideas of temporal distortion prevail in the discourse of flow research, where references are often made to “time flying”. Nonetheless, little research has investigated how flow affects time perception...