PLoS ONE
Articles in this Issue
Differences in sensory nerve block between levobupivacaine and bupivacaine at low concentrations in humans and animals
Physiochemical properties of levobupivacaine and bupivacaine are identical, but pharmacokinetic and pharmacodynamics properties differ due to stereoselective interactions at the molecular sites of act...
Genome wide association study reveals novel associations with face morphology
Genome-wide association studies (GWAS) on the Middle Eastern population, including the United Arab Emirates (UAE), have been relatively limited. The present study aims to investigate genotype-face mor...
Validity evidence for assessing social-emotional psychological strengths in Colombian adolescents using the SEHS-S
Background Covitality is a multidimensional hierarchical construct of core psychological strengths that synergistically promote resilience and well-being and that has been shown to be effective in pre...
Identifying priorities and developing collaborative action plans to improve accessible housing practice, policy, and research in Canada
This article describes the development of priorities and actions to improve the state of research, policy, and practice related to accessible housing in Canada for persons with disability or with acce...
Patient-Reported Outcomes among people living with Chronic Pruritus (PROs-CP): Protocol for a single-center, multistage, mixed-methods prospective cohort study in Thailand
Background Although there have been well-validated patient-reported outcome (PRO) measurements in dermatology practice, there is limited evidence of the adopted comprehensive aspects of PRO measures i...
Development of a functional electrical stimulation cycling toolkit for spinal cord injury rehabilitation in acute care hospitals: A participatory action approach
The purpose of our study was to develop a toolkit to facilitate the implementation of functional electrical stimulation (FES) cycling for persons with a newly acquired spinal cord injury (SCI) in the...
Correction: Health and wellness in the Australian coal mining industry: An analysis of pre-post findings from the RESHAPE workplace health promotion program
Fair food futures UK: Protocol for a mixed methods study exploring what approaches adopted by community food organisations are more likely to prevent the need for emergency food in two multicultural communities in Northern and Southern England
Introduction Food insecurity reduces people’s chances to live healthy and active lives and places a significant burden on healthcare systems. Levels have significantly increased in the UK since 2010,...
The impact of Duration of Untreated Psychosis on functioning and quality of life over one year of Coordinated Specialty Care (CSC)
Background This study examined the relationship between the Duration of Untreated Psychosis (DUP) and functional outcomes at baseline, 6 months, and 12 months after admission to Coordinated Specialty...
Prevalence and associated factors of diabetic ketoacidosis among patients with diabetes mellitus at the University of Gondar Comprehensive and Specialized Referral Hospital Northwest, Ethiopia
Background Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Diabetic ketoacidosis is one of the life-threa...
Exploring the science and data foundation for Federal public lands decisions
Public lands provide diverse resources, values, and services worldwide. Laws and policies typically require consideration of science in public lands decisions, and resource managers are committed to s...
Family correlates of behavioral problems among adolescents in Rwanda
Background Globally, 20% of adolescents exhibit behavioral problems. Behavioral problems are associated with individual and environmental factors. However, little is known about the contribution of th...
Digital assessment of walking ability: Validity and reliability of the automated figure-of-eight walk test in older adults
Background The Figure-of-Eight Walk Test (F8WT) can assess straight- and curved-path walking ability, but the validity and reliability of automated measurement of the F8WT using digital device has not...
Quantitative research on aesthetic value of the world heritage karst based on UGC data: A case study of Huangguoshu Scenic Area
The World Natural Heritage is a rare and irreplaceable natural landscape recognized by all mankind, with outstanding significance and universal value. Among them, the World Heritage Karst sites(WHKs)...
The role of iron deficiency and factors associated with anemia during pregnancy in Southeastern Tigray, Ethiopia, 2020
Background Pregnant women are more likely to experience anemia due to their increased need for nutrients, and anemia has been associated with unfavorable maternal-fetal outcomes. In Ethiopia, anemia r...
Quantifying the impacts of volume-based procurement policy on spatial accessibility of antidepressants via generic substitution: A four-city cohort study using drug sales data
Objective To assess the spatial accessibility and inequality of antidepressants and its correlation with VBP (Volume-based procurement) policy using procurement data from four representative Chinese c...
Characterizing pre-discharge interventions to reduce length of stay for older adults: A scoping review
Background Hospital pre-discharge interventions are becoming one of the leading strategies to promote early discharge. For older adult patients, it remains unclear what these interventions are and how...
Impact of federal funding for graduate medical education on residency program size: Evidence from the Affordable Care Act
Primary care and rural physician shortages are a present and growing concern to policy makers. We assessed three Affordable Care Act (ACA) provisions that changed the maximum number of residents teach...
Increasing rice yield with low ammonia volatilization by combined application of controlled-release blended fertilizer and densification
Controlled-release blended fertilizer (CRBF) and densification can increase rice yield and nitrogen (N) efficiency. However, the effects of CRBF combined with densification on rice yield, N absorption...
Modelling the impact of behavioural interventions during pandemics: A systematic review
Background Many studies examined the impact of behavioural interventions on COVID-19 outcomes. We conducted a systematic review to gain insight into transmission models, following...
Gaps, challenges and opportunities towards achieving the 95-95-95 targets in Cameroon: A systematic review and meta-analysis protocol
Background Given HIV elimination by 2030, the World Health Organization and the United Nations’ Programme on HIV/AIDS (UNAIDS) have set three programmatic goals that all countries should have achieved...
In vitro antibiofilm efficacy of ertapenem, tobramycin, and moxifloxacin against biofilms grown in a glass bead or CDC Biofilm Reactor®
Laboratory grown biofilms are used to simulate bacterial growth in diverse environmental conditions and screen the effectiveness of anti-biofilm therapies. Recently, we developed a glass bead biofilm...
Perception of four intellectual and developmental disabilities based on search engine and news portrayal
Background For people with intellectual and developmental disabilities, other’s perceptions of them based on their condition often begin before birth and go on to impact relationships, opportunities,...
Outcome of COVID-19 in patients with idiopathic inflammatory myopathy during the Omicron wave in China: A longitudinal observational study
Objective The coronavirus disease pandemic brought unknown challenges to patients with idiopathic inflammatory myopathy, who are often heavily immunosuppressed and have comorbidities. We aimed to inve...
Adolescent weight management counseling: The effectiveness of an online training program for primary healthcare professionals in Indonesia
Background Overweight and obesity are growing public health concerns globally for which innovative prevention and care delivery efforts are required. We recently developed a web-based training program...