PLoS ONE
Articles in this Issue
Multi-perspective analysis of skin microbiota in elderly eczema patients
Eczema is a common inflammatory skin disease in elderly people. It not only causes physical damage to elderly people but also seriously affects their mental health. The skin microbiota plays a vital r...
Population pharmacokinetic analysis of intravenous voriconazole in cancer patients
Purpose The pharmacokinetics of voriconazole have been studied across various populations but data specific to the Pakistani cancer population has not yet been reported. The aim of present study was t...
Correction: A novel technique using integral transforms and residual functions for nonlinear partial fractional differential equations involving Caputo derivatives
The influence of fitness mobile apps on workout behavior intention among Chinese young adults
Exercise was one of the most widely promoted methods to improve physical health while socially restricted. Despite the extensive notion of the advantages of sports activities, many young adults in Chi...
The relationship between preoperative serum indirect bilirubin and postoperative delirium in geriatric patients undergoing joint replacement
Background Postoperative delirium (POD) is one of the most common complications in geriatric patients following surgery. Physiological concentration of bilirubin possesses anti-inflammatory, antioxida...
Supporting healthcare in rural communities in Thailand: An exploratory qualitative study to understand the role and current mental health practices of village health volunteers
Introduction Village health volunteers (VHVs) are the backbone of primary healthcare in many low-and-middle-income countries, including Thailand, where healthcare professionals are scarce. Previous st...
Analytical solution of MHD bioconvection Williamson nanofluid flow over an exponentially stretching sheet with the impact of viscous dissipation and gyrotactic microorganism
Nanofluids achieve high thermal transport efficiency by uniformly dispersing small particles in base liquids, significantly enhancing the heat transfer coefficients and making them vital in various th...
Cognitive impairment and dementia—Are they linked to childhood health and socioeconomic status? A systematic review
Background Dementia is a major public health concern, with its incidence rising as the population ages. Recent studies suggest links between childhood health, socioeconomic status, and later-life cogn...
A novel use of HIV surveillance and court data to understand and improve care among a population of people with HIV experiencing criminal charges in North Carolina 2017–2020
Objectives To enumerate and describe the population of people with HIV (PWH) with criminal charges and to estimate associations between charges and HIV outcomes. We hypothesized th...
Correction: Combination of computational techniques and RNAi reveal targets in Anopheles gambiae for malaria vector control
A Bayesian game approach for node-based attribution defense against asymmetric information attacks in IoT networks
In the rapidly evolving landscape of the Internet of Things (IoT), traditional defense mechanisms struggle to counter sophisticated attribution attacks, especially under asymmetric information conditi...
Vertical bearing performance of inclined high-pressure rotary spray pile
Inclined piles are increasingly adopted in the foundation design of large-scale transmission line towers. Nine inclined pile tests were conducted in red clay soil to investigate the load-bearing and d...
A systematic review of sport-based adolescent mental health awareness programmes
Background Adolescent mental illness is of increasing concern, with a high prevalence in many parts of the world. Early engagement, detection and receiving support are warranted to reduce the severity...
Correction: A randomized, parallel group, pragmatic comparative-effectiveness trial comparing medication-assisted treatment induction methods in primary care practices: The HOMER study protocol
Disability-adjusted life years associated with COVID-19 in Brazil, 2020
Background We quantified the national- and state-level burden of COVID-19 in Brazil and its states during 2020 and contrasted it to the burden from other causes of disease and injury. Methods We use...
Correction: The impact of tax burden on welfare attitudes: Micro evidence from welfare states
Impact analysis assessment of UAS collision with a human body
This study investigates the safety risks of Unmanned Aerial System (UAS) collisions with humans, focusing on impact dynamics through controlled crash testing. Utilizing a custom-designed drop mechanis...
Drug regulatory affairs under focus: Knowledge and perceptions among pharmacists and pharmacy students
Objectives Pharmaceutical product development, registration, and post-marketing surveillance are the main concerns of the Regulatory Affairs (RA) profession in regulated pharmaceutical industries. The...
Nomogram for predicting olfactory disorder in obstructive sleep apnea: A retrospective study based on a multicenter database
Objective Obstructive sleep apnea (OSA) increases the risk of olfactory disorder (OD), which may serve as an early warning of adverse health consequences. In this study, we aimed to develop and valida...
Association of a CHEK2 somatic variant with tumor microenvironment calprotectin expression predicts platinum resistance in a small cohort of ovarian carcinoma
High-grade serous ovarian cancer (HGSOC) low overall survival rate is often attributed to platinum resistance. Recent studies suggest that the tumor associated-microenvironment (TME) is a determining...
Systemic immune-inflammation index is associated with clinical outcome of acute ischemic stroke patients after intravenous thrombolysis treatment
Introduction The systemic immune-inflammation index (SII) has been proven to predict the outcome in cancerous and non-cancerous diseases. We aimed to investigate the relationship between SII and other...
High-throughput 96-well plate-based porcine antibody isolation protocol
For decades, scientists have used column chromatography to purify an array of analytes. The same chromatography system has also been deployed for the isolation and purification of antibodies to increa...
Methodological considerations for assessing elder mistreatment of older adults with cognitive impairment: A scoping review protocol
Elder mistreatment (EM) of older persons with cognitive impairment is thought to be grossly underestimated in part due to communication barriers experienced by victims and a lack of consistent screeni...
Assessing concentration in the monoclonal antibody innovation market: A patent-based study
BACKGROUND Monoclonal antibodies (mAbs) are revolutionizing healthcare treatments due to their high efficacy and relative safety, despite their cost. Since they first appeared in the late 1980s, a rap...